The drug, Trulicity (dulaglutide), is once-a-week injectable treatment which aids in improving control of blood sugar levels in adults with type 2 diabetes.
India is the third Asian country to get the drug Trulicity after UAE and Japan, Lily officials said.
Trulicity is a once weekly injectable type 2 diabetes treatment that comes in a single-dose pen which doesn’t require mixing or measuring.
Trulicity belongs to a different class called glucagon-like peptide (GLP-1) receptor agonists. According to Lilly India, headquartered in Gurgaon, Trulicity is a once-weekly injectable prescription medicine that should be taken only on prescription from a registered MD (Internal Medicine) and endocrinologist, and should be used along with diet and exercise to treat type 2 diabetes. Diabetes mellitus, Hyperlipoproteinaemia, Insulin dependent diabetes mellitus, Insulin resistance, Non-insulin dependent diabetes mellitus, Obesity.
Vasculitis, Pneumonitis, Malabsorption of vit B12, Malabsorpton of folic acid, Megaloblastic anemia, Hypoglycemia.
The exact mechanism of action of metformin is unclear but it appears to reduce glucose absorption from the GI tract, reduce gluconeogenesis and enhance insulin sensitivity by increasing peripheral glucose uptake and utilisation. Sitagliptin inhibits dipeptidyl peptidase IV (DPP-IV), resulting in prolonged active incretin levels. Out of your order profit we share a large percentage to acquire medicines for poor people and their treatment. Changes in your urinary function: The first symptom of kidney disease is changes in the amount and frequency of your urination. Difficulty or pain during voiding: Sometimes you have difficulty or feel pressure or pain while voiding. Blood in the urine: This is a symptom of kidney disease which is a definite cause for concern. Extreme fatigue and generalised weakness: Your kidneys produce a hormone called erythropoietin which helps make red blood cells that carry oxygen. Feeling cold all the time: If you have kidney disease you may feel cold even when in a warm surrounding due to anaemia.
Ammonia breath and metallic taste: Kidney failure increases level of urea in the blood (uraemia). Nausea and vomiting: The build-up of waste products in your blood in kidney disease can also cause nausea and vomiting. To reduce your chances of getting severe kidney problems, see your doctor when you observe one or more of the above symptoms. Dark patches on skin are signs wherein discoloration of skin is noticed, such as occurrence of dark brown patches.
Hyperpigmentation: No matter what you call the condition whether brown patches, uneven skin-tone, dark patches on skin or discoloration, the condition is mostly manifestation of hyperpigmentation.
This is one of the rare medical anomalies which are characterized by anomalous pigmentation of eye or surrounding skin region of eyes. Tinea versicolor spot is a condition which is characterized with macular dark patches on skin that are often non-inflammatory.


There are some other causes of dark patches on skin that may include cafe-au-lait spots, Nevus of Ita, Solar lentigo, ageing spots, bruising, neurofibromatosis, stasis dermatitis, diabetes, etc. If the dermatologic issue seems to be a result of benign biological reactions which are not serious then one can try home remedies.
Milk and turmeric: One can make a mixture of milk and turmeric and apply it on the affected skin area. US drug maker Eli Lilly has finally launched its recently approved latest generation anti-diabetes drug in India. Trulicity’s efficacy has been proven and the drug is already up for sale in the United States and Europe. The medication got a green light from the US Food and Drug Administration (FDA) in September 2014 and European approval in November 2014. Glycaemic control may be affected by diuretics, corticosteroids, phenothiazines, thyroid products, oestrogens. Incretin hormones increases insulin synthesis and release from pancreatic ?-cells and reduces glucagon secretion from pancreatic ?-cells. Certain products discussed herein are available only upon prescription from a medical doctor or a qualified medical professional. There may be other reasons, but it is advisable to visit your doctor in case you notice it. In kidney disease lower levels of erythropoietin causes decreased red blood cells in your body resulting in anaemia.
This urea is broken down to ammonia in the saliva causing urine-like bad breath called ammonia breath.
You may feel a severe cramping pain that spreads from the lower back into the groin if there is a kidney stone in the ureter.
There are several medical irregularities that may lead to dark patches to appear on the skin.
In this condition discoloration of skin is recorded due to increased level of melanin in the skin.
These spots may appear as dark patches on the skin and are often found on Lumbosacral skin area, especially in dark-skinned individuals. In most cases merely one eye is affected due to the condition especially along the trigeminal nerve. The patient will suffer from scaly patches which will be discolored, ranging from white to dark brown. In some cases medicines may also cause dark spots on skin; these, medicines may include estrogens, tetracyclines, phenytoin, sulfonamides, etc.
Dark patches are also caused due to shin spots, a condition common in diabetic individuals.
These remedies do not have instant effect, but guaranteed effect can be seen if used regularly for 2 to 3 months. The medication replicates the effects of GLP-1, which helps human body release its own insulin following consumption of food.


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There is decreased oxygen delivery to cells causing generalised weakness and extreme fatigue. Pain may also be related to polycystic kidney disease, an inherited kidney disorder, which causes many fluid-filled cysts in the kidneys.
Melanoma is also medically referred to as Malignant Melanoma which is a severe kind of skin cancer as it can metastasize quite quickly to unaffected regions of the body. Doctor will first evaluate the condition and may try to determine whether pigmentation of the skin is at epidermal level or dermal level. One can make a mixture of water and lemon of equal quantity and directly apply to the affected skin surface. These ingredients have bleaching properties and using them regularly can reduce pigmentation of skin, even generally.
It is better to use home remedies for dark patches on skin as alongside measure with ongoing treatment. OMSI and its affiliates accept no responsibility for the reliance on or use of any information contained herein. Interstitial cystitis, a chronic inflammation of the bladder wall, causes chronic pain and discomfort.
In this condition the skin-complexion regulating agent called melanin becomes anomalous and increases hysterically. If oral medicines, tropical creams, etc, does not have any effect then treatments such as laser therapy, microdermabrasion can be used. Reader understands and agrees to the foregoing as well as all terms and conditions of the Legal Statement. However, there are possibilities that these patches may also indicate any serious underlying condition. In such a case the treatment usually involves tropical creams that could lighten the affected skin.
Usually these creams are designed with combination of tretinoin, certain corticosteroid and hydroquinone.
Even an unhealthy lifestyle with a high calorie diet, certain medicines, lots of soft drinks and sugar consumption can also cause kidney damage.
In case the dermatologic condition turns to be a cosmetic concern, then there are several techniques available to remove these patches. Glycolic acid and trichloroacetic acid based chemical peeling is suggested in patients with serious case of melasma which does not respond to tropical solutions.



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