Sodium-Glucose Linked Transporter 2 (SGLT2) inhibitors such as Dapagliflozin (Farxiga), Canagliflozin (Invokana) and Empagliflozin (Jardiance) are a new class of oral drugs available to treat type 2 diabetes mellitus (Type 2 DM). Type 2 diabetes is often labeled as adult onset, or I've also heard it as non-insulin dependent.
When you have diabetes , what happens is that the pancreas is slowing down, but still producing some insulin.
What happens in both types of diabetes, is that we lose our ability to make insulin, or do not utilize the insulin we make properly for sugar control.
Diabetic patients should look into multiple sources of information in order to figure out the best methods available to deal with their condition. Sometimes herbal preparations can help, though I personally have never sworn by them myself.
I will discuss weight and diabetes further later in my articles and perhaps add a doctor's article for reprint on this as I do have a wealth of materials I can use on the subject of weight and blood sugar control. Health Issue Tips Self Management has recipes, nutrition, diabetes support groups database, and much more. Alpha-glucosidase inhibitors These drugs will slow the adsorption of the starches you eat. Thiazolidinediones This category of drug types will make you more sensitive to insulin that you still make on your own. Meglitinides These drugs will stimulate your pancreas to make more insulin while the pancreas is still able to do so. D-phenylalanines These derivative type of medications help your pancreas make more insulin quickly.
DPP-IV Inhibitors These medicines boost incretin gut hormone production to help lower blood glucose levels. Get the latest news about the breakthroughs and discoveries that are going to change the future of the world.
Byetta can work alone, but it is often used in combination with other pills such as Metformin or Actos. With Byetta stimulating the creation of insulin in the pancreas, it should not be used in patients with type 1 or who require insulin to live. Talk to your doctor about this alternative if your sugars are not under control, but you are not ready for insulin. The miracle of Good Health is like a gift that we do not fully appreciate and tend to take for granted until we lose it. My Friend Had Type 2 and Complications Hi, I am telling story of diabetes, that was detected in my friend. Type 2 Diabetes Was My Wake-Up Call I was diagnosed with Type 2 diabetes three years ago. I Had An Unquenchable Thirst Last May, my husband and I were in Las Vegas on vacation, when I developed an unquenchable thirst. Diet, Exercise, and 1 Pill a Day I was diagnosed with TYPE II Diabetes approximately 7 years ago. Saw Palmetto with Pygeum & pumpkin oil lowered blood suger Not rated yetThis is my story on how I lowered my blood sugar. A Victim of Type 2 Diabetes Not rated yetThree years back it was my daughtera€™s wedding day and I was very happy for my daughter but physically I felt some uneasiness.
Diagnosed at the Age of 47 Not rated yetI was diagnosed with Type 2 diabetes in July of 2002, at the age of 47.
I Didn't Realize I Had Type 2 Diabetes Not rated yetI am writing this just to make people aware they need to get tested if diabetes runs in their family. Diabetic Type2 Not rated yetWhen I found out that I was a diabetic with Type 2, I couldn't believe that was happening to me.
Had Diabetes for Ten Years Not rated yetI have had diabetes for past 10 years, I am now 65 , so it was around the age of 55 that I realized I am diabetic.
I Learned I Had Type 2 Diabetes Not rated yetAbout five years ago I learned that I have type 2 diabetes.
Diabetes Makes Life Difficult! Not rated yetDiabetes has complicated my life in more ways than one. Berberine has been shown to lower blood sugar, cause weight loss and improve heart health, to name a few. Berberine is a bioactive compound that can be extracted from several different plants, including a group of shrubs called Berberis (1). Berberine has a long history of use in traditional Chinese medicine, where it was used to treat various ailments. Now, modern science has confirmed that berberine has impressive benefits for several different health problems (2). After you ingest berberine, it gets taken in by the body and transported into the bloodstream.
Inside the cells, berberine binds to several different “molecular targets” and changes their function (4). I am not going to get into much detail here, because the biological mechanisms of berberine are complicated and diverse. However, one of the main actions of berberine is to activate an enzyme inside cells called AMP-activated protein kinase (AMPK) (5).
It is found in the cells of various organs, including the brain, muscle, kidney, heart and liver. Berberine also affects various other molecules inside cells, and may even affect which genes are turned on or off (4). Bottom Line: Berberine affects the body at the molecular level, and has a variety of functions inside cells.
Type 2 diabetes is a serious disease that has become incredibly common in recent decades, causing millions of deaths every year.
It is characterized by elevated blood sugar (glucose) levels, either caused by insulin resistance or lack of insulin.
Over time, high blood sugar levels can damage the body’s tissues and organs, leading to various health problems and a shortened lifespan. Many studies show that berberine can significantly reduce blood sugar levels in individuals with type 2 diabetes (9). In fact, its effectiveness is comparable to the popular diabetes drug metformin(Glucophage) (2, 10). Decreases insulin resistance, making the blood sugar lowering hormone insulin more effective. It also lowered hemoglobin A1c by 12% (a marker for long-term blood sugar levels), and also improved blood lipids like cholesterol and triglycerides (12). According to a big review of 14 studies, berberine is as effective as oral diabetes drugs, including metformin, glipizide and rosiglitazone (13). It works very well with lifestyle modifications, and also has additive effects when administered with other blood sugar lowering drugs (2).
If you look at discussions online, you often see people with sky-high blood sugars literally normalizing them just by taking berberine. Bottom Line: Berberine is very effective at lowering blood sugar and HbA1c, which are elevated in people with diabetes. In a 12-week study in obese individuals, 500 mg of berberine three times per day caused about 5 pounds of weight loss, on average. The researchers believe that the weight loss is caused by improved function of fat-regulating hormones, such as insulin, adiponectin and leptin.
Bottom Line: Two studies have shown that berberine can cause significant weight loss, while improving all sorts of other health markers at the same time.
Many factors that can be measured in the blood are associated with an increased risk of heart disease.
Berberine has also been shown to lower apolipoprotein B by 13-15%, which is a very important risk factor (19, 20). Keep in mind that diabetes, high blood sugar levels and obesity are also major risk factors for heart disease, all of which seem to be improved with berberine. Given the beneficial effects on all these risk factors, it seems likely that berberine could drastically reduce the risk of heart disease. Bottom Line: Studies show that berberine reduces cholesterol and triglyceride levels, while raising HDL (the “good”) cholesterol. Cancer: Test tube and animal studies have shown that berberine can reduce the growth and spread of various different types of cancer (26, 27).
Antioxidant and Anti-Inflammatory: Berberine has been shown to have potent antioxidant and anti-inflammatory effects in some studies (28, 29, 30).
Infections: Berberine has been shown to fight harmful microorganisms, including bacteria, viruses, fungi and parasites (31, 32, 33, 34). Fatty Liver: Berberine can reduce fat build-up in the liver, which should help protect against non-alcoholic fatty liver disease (NAFLD) (35, 36).
Heart Failure: One study showed that berberine drastically improved symptoms and reduced risk of death in heart failure patients (37).
Many of these benefits need more research before firm recommendations can be made, but the current evidence is very promising. Bottom Line: Preliminary studies show that berberine may have benefits against depression, cancer, infections, fatty liver and heart failure.
Many of the studies cited in the article used dosages in the range of 900 to 1500 mg per day. Berberine has a half-life of several hours, so it is necessary to spread your dosage to several times per day to achieve stable blood levels.
If you have a medical condition or are on any medications, then it is recommended that you speak to your doctor before taking berberine.
Bottom Line: A common dosage recommendation is 500 mg, 3 times per day, half an hour before meals.
Although berberine has received a lot of attention in the scientific literature, it has yet to reach “mainstream” popularity. The people who stand to benefit the most are individuals with type 2 diabetes and the metabolic syndrome.
However, it may also be useful as a general protection against chronic disease, as well as an anti-aging supplement.
If you use supplements, then berberine may be one of the top ones to include in your arsenal.
I plan to continue taking it, and I look forward to seeing more research on this incredibly powerful health-promoting substance.
It is much more common than type 1, especially in adults, though nowadays it is even being seen in some children. Type 2 diabetics are often known as being insulin resistant, which simply means is that the insulin does not travel correctly within the body and go where it needs to in order to lower blood sugars properly. Problems that diabetics encounter are kidney disease, heart disease, and circulatory problems, not to mention the effect it has on the eyes.
The normal range should be between 70-98 fasting, and not above 130 after meals for anyone.
A good doctor will know how to treat it right and give you the nutritional information you need to eat the right foods for control of your sugar levels. Lifegress is updated daily with information about technological, scientific and medical developments that will impact everyone's lives for the better.
This injectable drug also known as Exenatide, is the first in a new class of medicines called incretin mimetics because it mimics the action of the hormone human glucagon like peptide-1. It is prescribed for type 2 patients who have not been able to achieve good control with pills alone. The complications I have include tingling feet when I haven't moved in a while and upon waking …Click here to write your own.
One of the main functions is activating an important enzyme called AMPK, which regulates metabolism. Berberine may also affect various other enzymes, molecules and genes related to blood sugar control. This study went on for 3 months, and the participants took 300 mg of berberine, 3 times per day.
The main side effects are related to digestion, and there are some reports of cramping, diarrhea, flatulence, constipation and stomach pain (10). I’m familiar with the guys who produce it, they are both physicians who have used it with excellent results in their patients.
Over time, at least in my own personal case, my own pancreas had gradually decreased in it's insulin production, to the point where I actually made very little insulin on my own.
It is very important that your blood sugar fluctuations are tightly controlled with good control of blood sugar levels. A blood sugar level above 126 or more fasting is indicative of a blood sugar problem, especially when taken fasting on two different occasions.
Unfortunately, pills may not do you good forever as in my case, but I was able to avoid insulin for 12 years by taking just oral medications. Glucagon-like peptides are produced and released into the blood by the intestine in response to foods. It causes really bad nausea in many patients as it did me, and sometimes cannot be tolerated well. The best way to control diabetes is diet control and that is exactly what …Click here to write your own.
It was at that time that my doctor prescribed a long acting insulin Lantus for me so that I would have enough in my system to lower my sugar levels.
They will increase the secretion of your insulin from the pancreas and slow emptying of your stomach., which in turn decreases the amount of glucose in your bloodstream. In other patients, I have heard it works just fine without side effects, and in others, the nausea will go away over time. Both website are dedicated to educating and informing people with articles on powerful and concealed information from around the world. They also suppress the release of glucagon by your liver, which can decrease hyperglycemic episodes.
I have spent the last 36+ years researching Bible, History, Alternative Health, Secret Societies, Symbolism and many other topics that are not reported by mainstream media. Byetta will reduce your sugars when they are high, but does not continue to do so after a normal level, therefore avoiding the risk of hypoglycemia.
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