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Algorithms have been developed that reduce the need for surgery, and include serial beta-HCG (human chorionic gonadotropin) measurements and transvaginal ultrasound (TVUS).
Although these algorithms are felt to be 97% sensitive and 95% specific, they may delay the diagnosis.

Absence of an intrauterine gestation with beta-HCG concentrations above this level is diagnostic of an EP (100% sensitive and specific). A decrease in the beta-HCG of ? 15% 8 – 12 hours after curettage is diagnostic of complete abortion.

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