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It looks like everybody’s favorite Love and Hip Hop reality star Stevie J and his wife (depending on who you ask) Joseline Hernandez is getting ready to add a new addition to their family. Over the weekend Joseline posted an interesting picture on Instagram which sparked pregnancy rumors. And it looks like Stevie J confirmed the pregnancy rumors while being interviewed on Milwaukee’s V100.7 radio station. When it comes to dressing for pregnancy, Winter presents more sartorial challenges than any other season. Joey Fatone has seemingly confirmed that Justin Timberlake and Jessica Biel are expecting their first child!After weeks and weeks of speculation that the 32-year-old actress might be pregnant, Timberlake's 'N Sync bandmate is revealing the cute couple are indeed going to be parents.
While Timberlake and Biel have yet to publically confirm the pregnancy news (and their reps are also staying silent), Fatone's confident confession seems to verify the pregnancy speculation.And this isn't even the first time Fatone has spilled the beans on Biel and Timberlake's baby-to-be. Your information may be shared with other NBCUniversal businesses and used to better tailor our services and advertising to you. Excluding pregnant women from drug trials on the basis of safety may actually endanger a greater number of pregnant women. When we were planning our honeymoon this year (which at that stage was already a babymoon), we had our eye on Burma.
We ended up choosing a malaria-free vacation destination instead and didn’t think anything more about it. With more women getting pregnant later in life, pregnancies are often accompanied by chronic conditions such as diabetes, asthma, depression, and lupus. Many of these risks remain unknown because pregnant women are a tricky cohort in which to test drugs. In 1977 the FDA excluded all women of childbearing potential from early phases of drug testing, a decision that was overruled only 20 years ago.
The lack of drug testing has led pregnant women (and the doctors who treat them) to a conundrum.
On the other hand, studies have found that women who stop taking medications they need can be at serious risk, too.
Anne Drapkin Lyerly, associate director of the Center for Bioethics at the University of North Carolina, co-founded the Second Wave Initiative, a project that promotes the responsible inclusion of pregnant women in biomedical research. Lyerly and Ruth Faden, another founder of the Second Wave Initiative and the director of the John Hopkins Berman Institute of Bioethics, argue that pregnant women are often seen as just vessels, with their own health regarded as secondary to the health of their unborn child.
This is particularly true in the case of pregnant women who take antidepressants, which some research has found to have adverse outcomes for the baby when taken throughout pregnancy. Her view is echoed in numerous studies, including a recent review of tuberculosis outcomes among pregnant women. In 2001, when bioterrorism was regarded as a major threat, the American College of Obstetrics and Gynecology recommended amoxicillin for the management of pregnant women exposed to anthrax.


Second Wave has spoken to the researchers in charge of the project, and there may be some opportunities to study pregnant women post-hoc.
Trials seem to also be on the rise, with one 2012 study finding that 264 drug trials have been conducted specifically on pregnant women in the United States within two years of the study.
Lyerly was particularly excited when the National Institute of Allergy and Infectious Diseases began a trial testing the H1N1 vaccine on pregnant women, who are more vulnerable to the potentially pandemic virus. Some studies have claimed that women would be reluctant to enroll in clinical trials because of fetal safety concerns. One woman told Lyerly that she would rather be given the vaccine and examined closely than just have her doctor prescribe it to her and hope for the best. Gone are the days of easy, breezy maxi dresses and tunics, replaced by the challenges of layering an already enhanced figure and figuring out how to stop those coat buttons from busting open. Online - Your source for entertainment news, celebrities, celeb news, and celebrity gossip. But for pregnant women with chronic or newly acquired conditions, choices about whether to take medication and what kind can have real risks and consequences, and doctors are often in the dark about exactly what these repercussions are.
In fact, a recent article in the Drug and Therapeutics Bulletin noted that at least 10 percent of pregnant women in the United Kingdom have a chronic illness requiring medication, and at least 40 percent of pregnant women in the U.K. Before the 1960s the placenta was generally thought of as an impenetrable barrier, protecting the fetus from contaminants. Either they risk ditching medications they need or they take drugs that haven’t been specifically tested on pregnant women and could pose an unknown danger. A study in the Journal of Allergy and Clinical Immunology found that 30 percent of women with asthma reduced or stopped their asthma medications in the first few months of pregnancy.
She recalls a case in which a woman with severe asthma was taken off her medication by her doctor. However, the needs of the baby and the needs of the mother should not be mutually exclusive. In 2007 a small trial, which drew blood from pregnant women who were already taking amoxicillin, found that it was impossible to achieve therapeutic doses. They refer to it as low-hanging fruit, where pregnant women who are already taking medication are monitored through blood or urine tests, for example, and then followed up with after the birth of their child. The National Children’s Study, for instance, is studying the effects of the environment on children from before birth to when they turn 21. Steven Hirschfeld, the director of the National Children’s Study, said that the current proposal, which is under external scientific review, is to collect prospective medication exposure information from approximately 50,000 women. The FDA is cautious about the inclusion of pregnant women in clinical trials and has said that it needs to be done on a case-by-case basis.
The five most common drugs studied were vitamins, metformin, misoprostol, progesterone, and insulin.


The World Health Organization and the Joint United Nations Program on HIV and AIDS released a guidance document for ethical considerations in HIV prevention trials. That's why we're introducing the concept of ultra-easy loungewear that works as well on a laid-back Sunday at home as it does when you're out and about on the town. But parts of Burma have malaria that is resistant to chloroquine, the preferred drug for treating and preventing the disease. Women who are expecting often take a cautious approach to drugs, especially because so little is known about their risks and benefits to their unborn child. Pharmaceutical companies are not willing to navigate the legal and ethical minefield of testing drugs on pregnant women, especially because pregnancy lasts only nine months, a short window in which the tests could pay off in additional sales. However, after 10,000 children were born in the late 1950s and early 1960s with birth defects as a result of their mothers taking thalidomide, opinion swung in the other direction. This occurred with anticonvulsant sodium valproate, which was found to be associated with an increased risk of impaired cognitive function among children whose mothers took the drug while pregnant.
A separate review reported that 6 percent of pregnant women with asthma are hospitalized for an acute attack.
I asked my doctor about other anti-malarial medication, and she said there wasn’t enough existing evidence about other drugs to confirm that they were safe for pregnant women. In the United States, this statistic is even higher, with 64 percent of women taking a prescription medication during their pregnancy. As a result, drugs are often prescribed to this population off-label, meaning that they haven’t been specifically approved for pregnant women.
Furthermore, a third of asthmatics intended to stop or stopped taking inhaled corticosteroids during pregnancy, with 44 percent of asthmatic women revealing that they had concerns about the ways that asthma medication and asthma attacks would affect their baby. But two pieces of groundbreaking legislation, the Pediatric Research Equity Act (2003) and the Best Pharmaceuticals for Children Act (2002), have resulted in many labeling changes for the pediatric use of drugs. The editors of the Drug and Therapeutics Bulletin argue that not only is enrolling pregnant women into drug trials important, it’s unethical not to do so.
The first full MEPREP study is evaluating the risk of birth defects in children whose mothers were prescribed sulfonamide antibiotics during their first trimester compared with mothers who were not taking antibiotics and mothers who were prescribed other antibiotics during their first trimester. I think he'll be very hands-on."Fatone isn't the only one who's confirmed the big baby news for Biel and Timberlake.



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