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The research, one of the first studies to focus on how in utero caffeine exposure affects a child's future intelligence (IQ) and behaviour later in childhood, found caffeine did not lead to a reduced IQ or increased behavioral problems.
According to the researchers, this was an era when coffee consumption during pregnancy was more prevalent than today, as there was little concern regarding the safety of caffeine. Researchers looked at the association between a chemical called paraxanthine, caffeine's primary metabolite, at two points in pregnancy. Researchers found there were no consistent patterns between maternal caffeine ingestion and the development and behaviour of those children at those points in their lives. Itching skin during pregnancy may be due to a number of causes that were present prior to conception. However, itchy skin in pregnancy may be a result of some underlying condition or cause that has been exacerbated due to the pregnant state. Of these type of conditions, allergic conditions resulting in itchy skin are the most common. The use of antihistamines to treat the itch are often of concern due to the debate surrounding the teratogenic properties of these drugs. Ask a Doctor Online Now!Itching within the first trimester of pregnancy is common and is usually not a cause for concern if there is no visible skin rash or concomitant signs and symptoms. There are certain causes of pruritus in pregnancy that may only occur or are more likely to occur in the pregnant state.
Also known as polymorphic eruption of pregnancy (PEP) or previously as toxemic rash of pregnancy.


More commonly affects a woman in her first pregnancy but may recur in subsequent pregnancies. Usually occurs in the areas where stretch marks (striae distensae) is most prominent – abdomen, thighs and buttocks.
Previously known as herpes gestationis due to its appearance but it is not caused by the herpes virus.
Tends to occur in the third trimester of pregnancy but may initially appear in the latter part of the second trimester. Progresses into large blisters (bullae) surrounded by rough, cracking skin (excoriated papules).
Poses a varying degree of risk to the fetus and an early delivery may have to be considered. Occurs when bile (bile salts) enter the bloodstream due to the diminished flow of bile out of the liver. Ask a Doctor Online Now!Please note that any information or feedback on this website is not intended to replace a consultation with a health care professional and will not constitute a medical diagnosis. Klebanoff.Researchers analysed a marker of caffeine in the blood of 2,197 expectant mothers who took part in the Collaborative Perinatal Project, conducted at multiple sites in the US in 1959-74. At other times, those conditions that appear after conception may have been developing or were bound to develop, irrespective of the pregnancy.
Alternatively, pregnancy was the trigger for the onset of a condition which the woman was predisposed to but had not as yet presented due to the lack of precipitating factors.


The increasing estrogen levels are known to exacerbate allergy-related conditions and may be also be noticed by females using hormone contraceptives or even hormone replacement therapy (HRT).
Certain antihistamines like chlorphenamine have a long safety record in pregnancy and can be used for palliating the itch although this should only be done after consulting a doctor or gynecologist. The latter may have been pre-existing and related to allergies earlier in life which may have also presented as as asthma or allergic rhinitis (allergic triad : eczema, asthma, hay fever). In both these instances, pregnancy was not the cause or precipitating factor and these itchy skin conditions were non-specific. Hormonal, immunological or unknown factors relating to pregnancy may serve as a trigger or aggravating factor for pre-existing or chronic skin diseases. Anxiety may play a role in this type of itching (psychogenic) as it is more frequently noted in first time mothers. However if the itching is persisting, getting worse, affecting sleep or other activities, then it should be investigated.



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