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Discuss the safety of using benzoyl peroxide during pregnancy with your doctor before you use the medicine. Clean your skin with a gentle and mild cleanser twice a day, then pat your skin dry with a clean towel. This is due to hormonal changes and increased fluid retention, which can increase your skin's production of oil. This may help keep your acne under control in addition to preparing your skin to be treated with benzoyl peroxide.

It should be in the strength recommended by your doctor, most of which are available over the counter. It is important to be careful of things you consume or use during pregnancy, since many medications can affect your unborn baby. Your doctor can help you decide if it is the best method of treatment during your pregnancy. Follow the directions on the packaging exactly, and do not apply more than a thin layer to your skin.

The Mayo Clinic recommends applying benzoyl peroxide to your skin 1 to 4 times a day, but you should ask your doctor which dosing frequency is right for you.

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