Frequently, we hear back from customers who have used our products to get organized and eliminate clutter, but that’s just scratching at the surface of what can be done. Roy Weissman is an online and in-person college professor for a number of well-known institutions, including Northeastern University and Mercy College. While Professor Roy Weissman has taught both online and in-person, he finds online education to have a number of unique challenges.
By using the ScanSnap iX500 Weissman is now able to download, print and provide written comments on all papers from his online students.
Students have many schools to choose from when deciding where to receive their online education. This website would like to use cookies to help us improve your user experience and remember your preferences.
Juno Therapeutics (NASDAQ:JUNO) last announced its quarterly earnings results on Monday, February 29th.
Here's what you need to know about Juno Therapeutics following the release of its first-quarter financials. After reporting its first-quarter financials, investors might be wondering if Juno Therapeutics (NASDAQ:JUNO) shares should be bought or sold. Tying it togetherJuno Therapeutics hopes its CAR-T approach can significantly improve outcomes for patients with relapsing leukemia, and if it can do that in mid-stage trials, then it thinks it has a good shot at winning accelerated FDA approval without having to conduct a large, costly, late-stage study first.
Nevertheless, Juno Therapeutics' deep pockets and the potential for commercialization next year make this one of the most intriguing clinical-stage drugmakers on the planet -- and one worth tracking closely. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.
Todd has been helping buy side portfolio managers as an independent researcher for over a decade. Juno Therapeutics' cancer study has now been allowed to resume a week after its clinical trials were suspended by the FDA. Last week, federal health regulators in the United States suspended the clinical trial of an anticancer treatment developed by Juno Therapeutics following the deaths of three participants this year. The company's experimental treatment known as JCAR015 is designed to treat adult patients with B cell acute lymphoblastic leukemia.
However, in May, one study participant passed away, while two more participants died in late June from swelling of the brain.
According to Seattle-based Juno Therapeutics, the problem did not stem from JCAR015, but from a chemotherapy drug called fludarabine, which is used during the pretreatment.
The company said last week that it will submit documents to the FDA including revisions in the trial protocol and patient consent forms.
Juno will resume its trials but without fludarabine and will instead use the chemotherapy drug cyclophosphamide, which was already part of JCAR015. Juno's JCAR015 treatment, which uses a new approach called chimeric antigen receptor (CAR-T), is "promising, but still unproven," according to The New York Times.
More specifically, the person's white blood cells are taken away from the body and changed to identify and kill cancer cells when returned.

Initial studies have shown that striking results in the treatment of lymphoma and leukemia, offering hope to patients, oncologists and investors. Juno was launched in 2013 in collaboration with scientists from the Fred Hutchinson Cancer Research, the Seattle Children's Research Institute and the Sloan Kettering Cancer Center. According to the Wall Street Journal, Celgene initially invested $1 billion in Juno, including a $150 million payment and an $849.8 million stock purchase.
Here is a perfect example of how a college professor utilized the ScanSnap iX500 to give his students a more personal education experience. He teaches courses in negotiations, marketing, new business models, business writing & presentation, and social media. To solve these challenges, he utilizes one of the most widely used education software platforms, Blackboard, to make articles, readings, videos, PowerPoint presentations and more to be accessible to his online students. Once he has done that, he can then scan all these documents and individually upload them to each student’s online file. As a professor for two educational institutions, Weissman strives to provide an optimal learning experience and education that students will ultimately benefit from, in their personal and professional lives.
Juno, which started trading from Dec 2014, is looking to revolutionize cancer treatments by engaging the body’s immune system to treat cancer and is developing cell-based cancer immunotherapies based on CAR and high-affinity TCR technologies. Evnin bought 8,000 shares of the company’s stock in a transaction on Monday, March 28th. Private Asset Management increased its stake in Juno Therapeutics by 23.8% in the fourth quarter. The Company is developing cell-based cancer immunotherapies based on its chimeric antigen receptor (CAR) and T cell receptor (TCR) technologies to genetically engineer T cells to recognize and kill cancer cells. Here are eight key numbers, plus a bonus, that offer additional insight into whether this company is worth owning in portfolios.
This is how many trials are currently under way to evaluate Juno Therapeutics' various CAR-T therapies. In April, Celgene Corp (NASDAQ:CELG) paid this sum to Juno Therapeutics to exercise its option to develop and commercialize Juno Therapeutics' CD19 targeting CAR-T therapies outside of the United States. This year, it decided to take advantage of that opportunity, and as a result, it handed Juno Therapeutics this much money last quarter in exchange for 1,137,593 shares.
Yes, the figure is down from the $1.22 billion reported at the end of 2015, however, it doesn't include Celgene's $50 million opt-in payment, which occurred early in the second quarter. After all the gives and takes, this is the loss Juno Therapeutics incurred during the first quarter on a GAAP accounting basis.
Juno Therapeutics management affirmed that this is the amount of cash it expects it will go through in 2016.
This is the number of CD19 negative pediatric patients diagnosed with ALL who were treated with JCAR018, a CD22 targeting CAR-T approach. Cancer research is notoriously hit and miss, and reported results so far have been from small studies involving a limited patient population.
Food and Drug Administration (FDA) has allowed Juno to resume its study, but only without a specific chemotherapy drug.

This includes overreactions in the immune system and neurological toxicity such as intense swelling in the brain known as cerebral edema.
He tries to be as personal as possible by utilizing direct feedback on discussion posts and make assignments specific to each student. While an in-person class offers participants the opportunity to submit and receive papers with handwritten comments, opportunities to create personalized experiences online is much more limited. This enables each student to receive highly personalized feedback and notes, something that he was unable to do previously.
Students enjoy his classes as well as appreciate the personal communications he provides, as it is evident from the positive ratings and comments he receives from the feedback surveys completed at the end of each of each course. Private Asset Management now owns 6,375 shares of the biopharmaceutical company’s stock valued at $280,000 after buying an additional 1,225 shares during the period. The company's research into next-generation chimeric antigen receptor T-cell (CAR-T) therapies is exciting, but it's also very expensive.
Studies are occurring in various cancer indications, but the most advanced study is of JCAR015 in acute lymphoblastic leukemia, or ALL.
Although JCAR018 is only in phase 1, all three of these patients are in complete remission three to six months after treatment. Additionally, there have been incidences of life-threatening cytokine responses observed in CAR-T patients, and that could pose some questions regarding safety down the road. Online students need to upload their documents for feedback, and when they do they usually only receive typed responses. Following the completion of the acquisition, the director now owns 50,000 shares of the company’s stock, valued at approximately $1,829,000.
According to management, enrollment in a pivotal study that could allow for a FDA filing for approval and commercialization of JCAR015 as soon as 2017 is progressing as expected. After all, Celgene is among the best in biotech at commercializing cancer-fighting drugs worldwide. CAR-T is part of a wider scientific trend in which the immune systems of patients are harnessed to fight cancer.
The purchase was disclosed in a document filed with the SEC, which can be accessed through the SEC website. However, while encouraged by Juno’s progress so far, we note that the pipeline candidates are still a few steps from approval and commercialization.
Also, Director Richard Klausner sold 24,000 shares of the business’s stock in a transaction on Wednesday, March 2nd. Creative Planning now owns 35,395 shares of the biopharmaceutical company’s stock valued at $1,556,000 after buying an additional 4,800 shares during the period.
Following the completion of the sale, the director now directly owns 895,259 shares in the company, valued at $36,186,368.78.

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