Sanjay Saint, MD, MPH, professor of internal medicine at the University of Michigan in Ann Arbor, and colleagues tried the new program in 600 hospitals.
Susan Huang, MD, MPH, a professor of infectious disease at the University of California, Irvine, wrote an editorial accompanying the study. The new clinical trial involved 119 locally advanced or metastatic urothelial cancer patients (average age 73 years).
Risk-stratifying patients requires a urologist's understanding of the natural history of disease, competing risks, and morbidities of interventions.
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Renal & Urology News publishes timely news coverage of scientific developments of interest to nephrologists and urologists, including in-depth coverage of all relevant medical conferences.
This material may not be published, broadcast, rewritten or redistributed in any form without prior authorization. Your use of this website constitutes acceptance of Haymarket Media's Privacy Policy and Terms & Conditions. The program Saint helped develop -- called the "bladder bundle" -- includes protocols, checklists, training, and information-sharing that help doctors and nurses reduce catheter use and prevent infections.
She told HealthDay that "while we've known the correct care processes for managing urinary catheters, we haven't been able to reliably reduce catheter-related infections." An intervention that focuses on changing the culture in hospitals to make them more responsive to the problem of infection control -- one that involves "rallying around a focused problem and ensuring team-based solutions -- is integral to improving infection control in hospitals," she said.


At the times of data analysis, the longest duration of response was 18 months, and 21 of 28 (75%) responses were ongoing.
About 10-15% of patients experienced severe side effects with atezolizumab, which could include hypothyroidism, liver function abnormalities, rash, or diarrhea.



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