Mucormycosis is a fungal infection of the sinuses, brain, or lungs that occurs primarily in people with immune disorders. Causes Mucormycosis is caused by common fungi frequently found in the soil and in decaying vegetation. In TED optic neuropathy, the optic nerve becomes compressed by the enlarged muscles at the narrow orbital apex where the nerve exits the orbit to enter the brain cavity.
The patient symptoms may include central visual blurring, loss of peripheral vision or colour desaturation. Objective measures of optic neuropathy include a loss in central visual acuity and colour vision, an afferent pupil defect, and infrequently congestion or pallor of the optic nerve. Ancillary testing includes coronal CT or MR Scans to confirm crowding of the orbital apex, standardized visual fields, and rarely VEP or optic nerve head photos.
Because the disease is usually in the active or progressive phase when optic neuropathy develops, some clinicians may arrange additional radiotherapy subsequent to the decompression to prevent further enlargement of the muscles and recurrence of neuropathy.
Success of therapy for TED optic neuropathy from both a clinical or research standpoint is based on specific improved measurements for central vision, colour vision and visual fields.
Symptoms of ocular and periocular soft tissue inflammation include orbital aching at rest or with movement, and eyelid or conjunctival swelling and redness.
The Clinical Activity Score (CAS) described and validated by Mourits and the Amsterdam Orbitopathy group assigns one point for each of the following: orbital pain at rest, orbital pain with movement, chemosis, caruncular edema, eyelid edema, conjunctival injection and eyelid injection. The VISA Inflammatory Score modifies the CAS slightly by widening the grade for chemosis and lid edema from 0-2.
Lid edema is graded as 1 if it is present but not causing overhanging of the tissues, and as 2 if it causes a roll in the lid skin including festoons in the lower lid.
The pain score is based on the patient’s report of deep orbit discomfort rather than ocular surface irritation (0 = no pain, 1 = pain with movement, 2 = pain at rest). Treatment of active inflammation in TED depends on its inflammatory score and evidence of progression. In general, if the inflammatory grade is 5 or more, or if there is subjective or objective evidence of progression in the inflammation, more aggressive therapy should be considered, including oral or intravenous corticosteroids, radiotherapy, and in refractory cases, immunosuppressive agents.
Combination therapy is receiving increasing attention in severe, progressive cases [26, 27] and interest is also turning to new immunomodulatory agents, such as anti-tumor necrosis factor agents (etanercept, infliximab) or B-lymphocyte directed therapy (rituximab). The symptoms for strabismus include a progression from no diplopia (double vision), diplopia with horizontal or vertical gaze, intermittent diplopia in straight gaze, and constant diplopia in straight gaze. Strabismus can be measured objectively by prism cover testing in different gaze directions.
Ancillary testing includes using the Goldmann perimeter to quantify ocular ductions in four directions.  The patient keeps both eyes open and follows the V4e light target, tapping a coin when the image becomes double. Figure 4b: Once the inflammation controlled and the strabismus measurements are stable, prisms may be offered or alignment surgery with adjustable sutures can be performed. Symptoms in this category include appearance concerns such as bulging of the eyes, eyelid retraction and fat pockets, as well as exposure complaints of foreign body sensation, glare, dryness or secondary tearing. Objective measures of appearance change include eyelid retraction (measured in millimeters), proptosis (measured with the Hertel exophthalmometer), and documentation of redundant skin and fat prolapse.  Measures of exposure include corneal staining or ulceration. Rarely a tarsorrhaphy (temporarily suturing the upper and lower lids) or emergency orbital decompression may be required for severe exposure or corneal ulceration.
Once the inflammatory phase has settled, management for proptosis might include orbital decompression and for eyelid retraction may include upper lid lowering from an anterior or posterior approach or lower lid elevation.31  These surgical measures often relieve many of the exposure complaints. ITEDS is a non-profit society dedicated to educating the public and physicians about thyroid eye disease as well as conducting research to understand the disease and lead to prevention and cures. The triangular fibrocartilage complex (TFCC) is found within the wrist joint at the little finger side. Continuando con nuestro monografico sobre los riesgos del embarazo multiple, hoy hablaremos de la preeclampsia, una complicacion del embarazo relativamente comun pero a la vez bastante peligrosa para la madre y los bebes, por lo que es fundamental recibir un seguimiento medico adecuado. Aunque la preeclampsia puede aparecer tambien en un embarazo unico (en el caso de Espana se calcula que se manifiesta entre un 1% y un 2% de los embarazos), la incidencia en embarazos multiples  es significativamente mayor. La preeclampsia, tambien conocida como toxemia del embarazo, se caracteriza por la aparicion de un cuadro de hipertension (subida de tension) junto con un aumento del nivel de proteinuria en la orina (existencia de proteinas en la orina en una cantidad elevada). Asi, durante la preeclampsia el cuerpo de la madre inicia un proceso de rechazo a la presencia del feto y la placenta. Hay que tener en cuenta que la aparicion de un cuadro de hipertension durante el embarazo no siempre significa que se trate de una preeclampsia. Generalmente la preeclampsia se manifiesta durante el embarazo, aunque tambien puede aparecer hasta seis semanas despues del parto (preeclampsia postparto). La conclusion es que la exposicion repetida al semen establece la tolerancia inmunologica necesaria para un embarazo sano con exito. Dado que se ha comprobado existe una cierta predisposicion en mujeres con familiares con antecedentes de preeclampsia, algunas teorias apuntan a que el origen estaria en una susceptibilidad genetica.
Dado que se han documentado casos de preeclampsia en pacientes con embarazos ectopicos o molares, otras teorias apuntan a que la clave estaria en la placenta, siendo la severidad de la preeclampsia proporcional a la masa placentaria (como en el caso de los embarazos multiples). Esta imagen muestra el estrechamiento de los vasos sanguineos de la placenta propia de la preeclampsia, lo que provoca una restriccion del flujo sanguineo que debe llegar hasta los fetos. Segun esta teoria el cuerpo de la madre produciria un agente que es toxico para las celulas endoteliales de la placenta debido a un desequilibrio en el sistema oxidativo.
La preeclampsia, si no recibe el tratamiento adecuado, puede provocar en la madre fallos renales o hepaticos, problemas de coagulacion, problemas cardiovasculares o incluso danos cerebrales. Por lo que respecta al riesgo para los fetos, la preeclampsia aumenta el riesgo de desprendimiento prematuro de placenta. Tambien produce oligoamnios (disminucion del liquido amniotico), lo que puede provocar alteraciones en el crecimiento fetal y aumenta las posibilidades de que se produzcan complicaciones con el cordon umbilical,  dificultando el parto. Por otro lado, el estrechamiento de los vasos sanguineos provoca que el riego sanguineo a ciertas areas de las placentas se vea restringido, por lo que los fetos reciben menos alimentos y oxigeno produciendose un retraso en el crecimiento intrauterino (CIR, RCIU).
Ademas, debemos tener en cuenta los riesgos intrinsecos a la prematuridad y el nacimiento con bajo peso, ya que con frecuencia la aparicion de preeclampsia determina la terminacion anticipada del embarazo mediante cesarea.


A pesar de lo anterior, si la gestante recibe un seguimiento medico adecuado y no desarrolla un cuadro de especial gravedad, el pronostico suele ser bueno.
Existencia de un embarazo multiple: La preeclampsia es de 3 a 5 veces mas frecuente en el caso de embarazos multiple. El riesgo es mas elevado si se trata del primer embarazo de la mujer (hasta el 85% de los casos), o bien si se trata del primer embarazo con esa misma pareja (de conformidad con la teoria del origen inmunologico, algunos estudios indican que la exposicion prolongada al semen de la pareja tiene un efecto protector contra la preeclampsia). Antecedentes de diabetes, hipertension arterial o la existencia de una enfermedad renal previa. En la segunda parte del post veremos en detalle los distintos grados de severidad de la preeclampsia (preclampsia leve, preeclampsia grave, eclampsia y sindrome de HELLP), y hablaremos acerca de los sintomas que deben alertar a la mujer gestante, el tratamiento que suele recibir la preeclampsia y algunos factores de prevencion.
Rheumatoid Arthritis is an autoimmune disease in which body’s own cells start functioning against it. It is caused when the body develops self destructive process due to some endocrine or genetic tendencies where body’s own cell starts functioning against it resulting in destruction.
The treatment in homoeopathy is directed towards the cure of the cause and not toward the effect. There are no known reason why the chromosomes are altered, there are also no definite risk factors associated with Ewing’s Sarcoma.
Fever –  Although this is a general defense mechanism of our body against systemic infection and other foreign bodies, this can be present in a patient with Ewing’s Sarcoma. Swelling – This is also a general defense mechanism of our body to fight against a local infection.
History of previous cancers– This is included in our Risk Factors because cancers are can be treated using Radiotherapy, and Radiotherapy can cause a mutation of normal cells. Presence of an inborn disease– This can cause a change in chromosomal structure in children, especially the newborn. To fully diagnose Ewing’s Sarcoma, we need to have a series of tests done to the patient.
Advanced Imaging Tests – This includes MRI and CT Scan, they are both specialized imaging test that is used to scan the tumor deeper.
Children is the most common victim of Ewing’s Sarcoma, using that statement, we will need to use chemotherapy as a last resort treatment regimen. Since Ewing’s Sarcoma is a type of cancer, we can give the patient chemotherapy sessions. A combined therapy is developed and it produced an opportunity to cure this type of cancer. Age – this will affect the treatment tolerance of the patient, some researchers say that a young patient has a low tolerance to cancer treatment. Size of tumor – this is to know if the tumor is metastasized to other adjacent body organs.
Location of the tumor – this will affect the prognosis of the child because the location of the tumor will affect the treatment modality to be used and it can also affect the treatment’s efficiency if the tumor is superficial or deep within. Enter your email address to subscribe to this blog and receive notifications of new posts by email.
This website is for informational purposes only and Is not a substitute for medical advice, diagnosis or treatment. It is a medical condition in which there is inflammation on the lymph nodes, liver, lungs, eyes or skin and underlying tissues. If the skin surface is affected, he may develop rashes on the skin, hair loss, followed by appearance of skin sores on his legs. Normally, no treatment is required for sarcoidosis since the infection will heal on its own or by body’s immunity.
This interferes with flow of information through the optic nerve connecting the eyes to the brain. As a summary grade, VISA lists optic neuropathy as present or absent since most clinicians would attempt some treatment for this condition if present.
The common treatment for TED optic neuropathy initially is high dose corticosteroids either by intravenous route (1 gram Methyl-prednisolone over 30 minutes on alternate days for 3 treatments) or oral route (100 mg prednisone daily on a tapering dose) with an expectation that vision should improve within days of therapy. Radiotherapy is administered using a lateral port focused behind the globe to minimize the risk of retinal or lens exposure; it is divided into 10 fractions of 200 rads over two weeks [23] and is contraindicated in diabetics because of the risk of inciting or aggravating retinopathy. The worst scores from any of the four eyelids are recorded in the inflammatory score table on the far right section of the table. The additional grading scores for chemosis and lid edema allow for documentation of more subtle changes in inflammatory features between visits. If the score is less than 4 out of 10, and there is no deterioration based on history or sequential clinical examination, conservative management is offered with reassurance, cool compresses, nocturnal head elevation, and non-steroidal anti-inflammatories. This is usually made worse by loading the wrist through activities such as press ups or pushing up from a chair.  Swelling may also be present and this may come on rapidly in an acute injury situation or gradually over time through micro-damage to the cartilage in repetitive activities.
In these cases recovery may be prolonged and good post-operative physiotherapy support is important to optimise your recovery.
De igual modo, el hecho de que una mujer sufra una hipertension cronica no implica necesariamente que deba desarrollar una preeclampsia durante el embarazo, pero si debera estar mas controlada.
Segun la misma la causa de la preeclampsia residiria en una respuesta inmune anormal del cuerpo de la madre al feto y la placenta. Incluso algunos expertos se han atrevido a sugerir la implicacion de un gen presente en los cromosomas 1, 3, 9, o 18. Asi, la causa podria estar relacionada con la presencia de unos vasos sanguineos en la placenta mas delgados de lo habitual, lo que generaria una reaccion inapropiada del utero a la presencia de la placenta. En los casos mas graves la preeclampsia podra evolucionar en una eclampsia o en el sindrome de HELLP.
Algunas investigaciones realizadas han puesto de manifiesto que entre el 20% y el 40% de las gestantes cuyas madres padecieron preeclampsia la desarrollaron tambien, asi como entre el 11% y el 37% de las gestantes cuyas hermanas sufrieron de preeclampsia durante el embarazo.


It is a psychosomatic disorder where the autoimmune tendency like self reproach etc goes on physical level gradually and disorder occur. This means chief culprit is our immune system which is destroying our body, our organs and there is no role of bacteria and viruses.
The mistake of recognising our self tissues as foreign which is the root cause, is tried to be corrected. This condition is rare that is why we have few studies to use and the data are only able to describe the characteristics of Ewing’s Sarcoma. Please note that this can also be associated with other disease that is why fever is not a definitive symptom of Ewing’s Sarcoma.
This is not a definitive symptom because this can also be a pain from a broken bone or any other causes. This is to ensure an accurate diagnosis because there are other types of cancers that can affect the bones, and the patient may have a previous cancer that may have reached the bones. Chemotherapy is a treatment regimen that halts the growth and multiplication of the cancer cells, but this therapy will also halt the growth and multiplication of all cells in our body.
This method will kill the cancer cells; however, this can also kill our normal cells in the body.
The combined therapy is a combination of chemotherapy and surgery (radiation therapy can be also used too). A good prognosis can be decided early in the treatment phase when the initial chemotherapy sessions produced a good response from the tumor. But when the lymph nodes or any other internal organ gets inflamed, tiny clumps of tissue are formed inside. There is also chance for getting this condition if you work in the atmosphere prone to high sensitivity. However, treatment is to be done depending on the condition of the patient and the organ which is infected. However if the lung is infected severely, causing lung tissue damage, heart failure and lung scarring which may be fatal. Symptoms of rhinocerebral mucormycosis are most likely to occur among immunosuppressed people. Depending on where the symptoms are, CT scans or MRIs may be done.
The severity of the neuropathy is reflected in the individual measurements of central and colour vision. In most cases, this treatment will cause incomplete or only temporary visual improvement so that surgical decompression of the medial wall is required (through a Lynch, transcaruncular or endoscopic transethmoidal approach) or through a lateral approach (thinning the outer boney wall of the orbit near the apex) in order to relieve pressure more permanently on the optic nerve at the crowded orbital apex.
An additional point is assigned for diurnal variation of symptoms, to reflect the variability in congestion typically seen during the active phase. Otros han considerado que la preeclampsia esta relacionada con variante anormal de la molecula de angiotensinogeno. Esto explicaria que la preeclampsia tenga una mayor incidencia en madres primerizas debido a un menor desarrollo de la vasculatura uterina. Ewing’s Sarcoma is caused by an alteration in the chromosomal arrangement of the child after birth. In that case, if we use a chemotherapy, this will stunt the growth and development process of the child. It can also kill cancer cells by having the correct amount of radiation pointed to the location of the cancer cells. Also, bone marrow transplant can be the future treatment to treat and prevent this type of cancer.
If the lungs are infected, the person may get mild to moderate chest pain, dry cough, and shortness of breath, fever, fatigue and overall discomfort. If there is infection in the eyes, there can be burning sensation, dry eyes, itching, swelling of eyes and whitish discharge from the eyes. Since the disease can infect any organ, several tests has to be done for identifying the disease. When disease progresses, deposition of fibrous tissue on the cartilage starts which is called pannus. No where the genetic tendency is consider to cure the system, thus they treat the disease in the man and homoeopathy treats the man in disease. Although we have discussed that this condition targets children, it can also appear in adults.
Although that is a fact, this logic is not followed by doctors because they believe that we should intervene with Ewing’s Sarcoma immediately. However, patients who have their tumor metastasized to the lungs has a greater prognosis than those who have their tumors metastasized to the bone. Surgical removal of infected tissue may be disfiguring because it may involve removal of the palate, parts of the nose, or parts of the eye. Due to this destruction of cartilage occur resulting in fusion of bones which is known as ankylosis. This conflict caused a controversy whether to choose a safer treatment or use chemotherapy. Withoutt his aggressive surgery, however, chances of survival are greatly decreased. Outlook (Prognosis) Mucormycosis has an extremely high mortality rate even with aggressive surgical intervention.
Now the immune system no more behaves in a hostile manner on the joints, joints are healed from inside and become healthy and the pains and swelling disappear by themselves. Patient can observe a lot of mobility in the deformed joints and they can make use of them painlessly.



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