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16.07.2014

Herpes vaccine cure, herpes type 1 causes - For You

Author: admin
While current treatment options for genital herpes have been successful in limiting the number of outbreaks the patient experiences over time, there is still no cure for this highly infectious sexually transmitted infection (STI). According to the Centers for Disease Control and Prevention, each year 776,000 people in the United States develop new genital herpes infections, caused by either the herpes simplex virus type 1 (HSV 1) or type 2 (HSV 2).
Genital herpes can be spread from person to person through anal, vaginal, or oral sex when HSV 1 or HSV 2 escapes from soars in the groin area. Researchers working on this genital herpes vaccine recruited 156 patients who had tested positive for HSV 2. Health care professionals urge people affected by genital herpes to abstain from sex during an outbreak of genital herpes sores. Initial, positive results have been reported for a therapeutic vaccine candidate for treating patients with genital herpes. Wald and her team presented the initial findings of the first-in-human clinical trial of the novel GEN-003 T cell vaccine Sept.


The vaccine contains, among other components, a proprietary adjuvant, trademarked Matrix-M.
A study funded by the pharmaceutical company AiCuris has produced a new drug known as pritelivir that shows promise as a future treatment option for type 2 genital herpes. Considering signs and symptoms of herpes can go unnoticed or can be mistaken for another skin condition, HSV 2 carriers can be unaware of their condition.
This first-in-class, investigational, protein subunit vaccine, GEN-003, is under development by Genocea Biosciences Inc. T cell vaccine research is trying to find safe, effective ways to spur this protective reaction. However, an exploratory analysis suggested that the interval between the first immunization with GEN-003 and the next recurrence of genital herpes might be longer in those receiving the actual candidate vaccine, rather than the placebo injection. Wald is enrolling women infected with herpes simplex virus 2 in a study to see whether the drug tenofovir, given orally or as a vaginal gel, reduces genital shedding of the virus.


Throughout the study each participant was asked to record instances of genital herpes signs and symptoms.
Three of the major antiviral drugs meant to keep genital herpes outbreaks at bay include acyclovir (Zovirax), famciclovir (Famvir), and valacyclovir (Valtrex).
Genocea, located near Boston, is a clinical-stage biopharmaceutical company for the discovery and development of T cell vaccines to prevent and treat infectious diseases.
People with a compromised immune system are especially at risk for developing genital herpes.



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