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28.03.2015

Herpes disease research, genital herpes treatment for men - For Begninners

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New research suggests that just one or two individual herpes virus particles attack a skin cell in the first stage of an outbreak, resulting in a bottleneck in which the infection may be vulnerable to medical treatment. Unlike most viruses that spread to new cells by bombarding them with millions of particles, herpes simplex virus type 1 (HSV-1) — a virus that causes cold sores and genital lesions — requires just one or two viral particles to infect a skin cell in the first stage of cold sore formation, Princeton University researchers reported in the Proceedings of the National Academy of Sciences.
Princeton University research suggests that a common strain of herpes virus causes cold sores with only one or two viral particles, resulting in a bottleneck in which the infection is more vulnerable to medical treatment. In the case of herpes viruses, Enquist said: "The number of different genomes that infect the cell is remarkably low, so any mutations that weaken the virus are unlikely to survive. Model of herpes virus spread from neuron to skin cell Herpes virus particles move via axonal transport inside a neuron.
The researchers' findings suggest that other viruses related to HSV-1 — known as alpha-herpes viruses — may have similar bottlenecks, Taylor said, including herpes simplex viruses type 2, which causes cold sores and genital lesions, and varicella zoster virus, which causes chicken pox and shingles.


Julie Pfeiffer, an associate professor of microbiology at the University of Texas Southwestern Medical Center, said the Princeton research is the first to tally how many viral particles are involved in HSV-1 infection — and reveal that as the virus' weak point. To determine the number of virus particles that infect the skin cell, the researchers constructed three genetically unique viral genomes labeled with either red, green or blue fluorescent tags, and then infected cells with the particles and analyzed them for the presence of the three colors.
Genital herpes is a disease caused by the herpes simplex virus which is called as HSV in short.
Symptoms which are sufficient for symptomatic confirmation of the Herpes Simplex (HSV) appears as a blister or as multiple bllisters on or around affected areas-usually the mouth, genitals or rectum.
This test detects the antibodies that are made by the immune system to fight a herpes infection. Sakthi’s Hospital And Research Center are pioneer in the treatment of Sexually Transmitted diseases like Syphilis, gonorrhea, etc.


Treatment for Sexually Transmitted DiseasesSexually transmitted diseases are called as STDs in short, these are infections which are transmitted by having sex with an infected partner.
Humans are infected by two closely related but distinct herpes simplex viruses, Herpes Simplex Virus Type I (HSV-1), also known as oral herpes, and HSV-2, also known as genital herpes.
He and Enquist worked with co-author Oren Kobiler, a former Princeton postdoctoral researcher now at Tel Aviv University.



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