Dental implant survival in irradiated oral cancer patients,best light machine gun mw3 survival,survival rifle pistol combo - Try Out

Dental implants are often used oral rehabilitation following treatment for head and neck cancer. The aim of this review was to compare the success rate of implants placed in irradiated human bone tissue with that of implants placed in non-irradiated areas.
40 studies (1 randomised, 18 prospective, 21 retrospective) involving a total of 2220 patients were included. 13 studies identified the number of implants placed, 2185 in the mandible and 796 in the maxilla. Irradiated patients received doses ranging from 10 to 145 Gy, the average time between radiotherapy and implant placement was 11.82 months (range 1-240 months).
Kaplan-Meier analysis indicated a survival rate of 84.33% during the period from 0 to 192 months for irradiated patients.
Dental implants placed in irradiated areas have a lower survival rate than those installed in non-irradiated areas, and possible complications are a high-risk threat throughout the life of these patients. While the reviewers have searched 3 major databases restricting their included studies to those published in English may mean that some relevant studies have been excluded. Smith Nobrega A, Santiago JF Jr, de Faria Almeida DA, Dos Santos DM, Pellizzer EP, Goiato MC. Derek Richards is the Director of the Centre for Evidence-based Dentistry, Editor of the Evidence-based Dentistry Journal, Consultant in Dental Public Health with Forth Valley Health Board and Honorary Senior Lecturer at Dundee & Glasgow Dental Schools. While surgery is the most common treatment for this group of patients this is frequently combined with radiotherapy.
Randomized controlled trials, prospective, and retrospective studies with a minimum of 5 patients undergoing radiotherapy, receiving dental implants and reporting implant survival data were considered.
Survival rate was assessed using Kaplan-Meier analysis and risk ratio (RR) with a 95% confidence interval (CI) was used for dichotomous outcomes. 3 studies reported on patients for whom radiotherapy was performed after implant installation. The authors have also chosen to include both pro- and retrospective study designs and retrospective designs are more prone to bias. Irradiated patients and survival rate of dental implants: A systematic review and meta-analysis. As radiotherapy reduces the vascularity and regenerative ability of bone tissue it can impact on the survival rate of implants.
Details regarding the selection process and quality assessment of the included studies is also limited and no information on the authors quality assessment of the individual studies is provided to inform the reader. A sensitivity analysis comparing the relative risk of failure between the pro- and retrospective studies would have been helpful. Consequently while this review provides an indication of implant survival rates in this group of patients the findings should be interpreted with caution as given the high proportion in retrospective studies there is a likelihood that survival is over estimated and the risk of failure underestimate.




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