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lisa fouladi: Yeah, I'm gonna go ahead and start the call. It's the top of the hour. This is Lisa Foladi. Welcome to this month's case study call I host. This call on behalf of Dr. Rita Marie. I'm 1 of her coaches. So right now there are only 2 of us here Lindsay and Deborah

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lisa fouladi: and and there have been no cases submitted. So you can just ask me questions. You know, so that would be great. Any questions you have about anything regarding, you know, having to do with any pt.

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lisa fouladi: otherwise we're gonna end the call. So all right. Lindsey.

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lisa fouladi: did you were. You gonna say something?

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lisa fouladi: I that's were you gonna say something, Lindsey?

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Lindsay Mille: Yeah, I mean, I I actually had something I wanted to submit that I didn't get it in time. Would this be a good time to do it?

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lisa fouladi: Yeah, you don't have to submit it. Just

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lisa fouladi: Do your screen share, and we'll just review it together.

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Lindsay Mille: You know what I'm gonna do? I'm gonna I'm gonna hop off. I'm on my cell phone. I'm gonna hook back up with my computer. And I can show you I just got some recent tests back from their their mold test. And I would love to share it with you if we have time. That'd be just great

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lisa fouladi: Of course, of course that's great.

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Lindsay Mille: I can actually stay on here as I go over to.

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Lindsay Mille: I thought it was just gonna come on this.

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Lindsay Mille: Then I'm so excited

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lisa fouladi: Well.

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Lindsay Mille: Okay.

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lisa fouladi: Lisa always always submit it. Anyhow, you know. Deborah, what were you gonna say?

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Deborah N: Oh, well, while she's reconnecting I'll just ask you a quick question. I was in touch with with Annette

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Deborah N: last week, and she assigned me to be

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lisa fouladi: You are now

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Deborah N: So my advisor and I was wondering how we connect

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lisa fouladi: I'm just about to send you an email to either schedule, a call, or, you know, to I don't know how far along you are in the program.

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Deborah N: I'm just starting level 3

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lisa fouladi: So you're quite far off. Okay? So I'll just look for an email from me in the next sort of day or 2. And do you want to schedule a call? Or do? We can just do email correspondence, and save, could you only get one call? You know, save the call for when you really need it. I guess that would be the thing. But I'll I'll send you an email within the next day or so.

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lisa fouladi: and then, and you can just up update me from there. Okay, cool

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Deborah N: Oh, okay, great, perfect. Thank you so much.

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lisa fouladi: You're welcome.

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lisa fouladi: Alright, Lindsay, so why don't you share your screen?

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lisa fouladi: You're on mute

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Lindsay Miller: Oh, my gosh! I am so wasn't prepared. I'm so sorry

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lisa fouladi: Don't worry, don't worry, don't worry.

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lisa fouladi: It's just you know what we have all the time in the world.

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Lindsay Miller: You're so great

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lisa fouladi: Oh!

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Lindsay Miller: It should be here. Some. I see other people hot, hot, downloaded test reports.

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Lindsay Miller: Okay, I found half of it, and maybe somebody else should just go first, st while I find the

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Lindsay Miller: as I find

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lisa fouladi: For those who just hopped on that would be Rob and Marva. No cases were submitted this time, so I kind of opened it up to the group. Whoever was here, and Lindsay said she was, gonna submit something, but she thought she was too late. By the way, people always submit, because you never know who has submitted, who hasn't submitted.

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lisa fouladi: and and you know, if we have too many for one month, we can always push it to the next. But yeah.

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lisa fouladi: But if you have any questions while Lindsey's getting her case, organized Marva, do you have any questions you unmuted yourself

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Marva Watkins: Well, I just have trouble finding where the links for these meetings.

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Marva Watkins: because I got something that said it was Google meet.

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Marva Watkins: And then I went to that.

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Marva Watkins: and there was nothing there so

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lisa fouladi: Well, the those calls are never on Google meet. They're always on zoom

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lisa fouladi: and the place to reach out is the help desk.

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lisa fouladi: When you know.

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lisa fouladi: Yeah. Reach out to help desk@drritamarie.com when you can't find the link

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lisa fouladi: and they'll be able to help you hopefully.

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lisa fouladi: Sorry. But you just ignore Google meet. There should be a zoom link, a meeting link

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Lindsay Miller: Hmm.

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lisa fouladi: Are you ready now, Lindsey

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Lindsay Miller: You know. Have one of them, and I'm looking for the other one right now. My goodness, my!

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Lindsay Miller: I'm looking for it. I'll show you the one

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lisa fouladi: Okay.

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Lindsay Miller: While I look with the other one. So I did 2. I did a mitotoxins for my house, and and then I did one that I'm looking for. That is what the toxins that are in my body

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lisa fouladi: No.

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Lindsay Miller: And they do they do match. So here's the erme that I did

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lisa fouladi: Okay.

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Lindsay Miller: I don't know if this is anything that you can help with. I think the other one is the

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lisa fouladi: So where is the mold predominantly? Did you have a flood or something like that? What made

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Lindsay Miller: 2 seconds.

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lisa fouladi: Mold.

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Lindsay Miller: What I what I realized was, is that like, just like, I just having this like constant headache with the brain just feeling like it's it's kind of like I'm hungover like the brain is just like pushing up against the head all the time.

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Lindsay Miller: And I just realized I was like, you know, I think this has to do with mold. And so I just went and tested it, and I don't. In this armies report. It's my mold index is 4, which is not high.

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Lindsay Miller: This is not readable here. I don't know. This is oh.

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lisa fouladi: Mind your what is the what is high 6.8, or what is high on the scale

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Lindsay Miller: It's basically 0 to 20. And hmm,

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Lindsay Miller: it's basically 0 to 20. And I'm a 4

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lisa fouladi: Okay.

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Lindsay Miller: You know. But then I ordered one from Rita Marie, and it was testing in my body, and I just don't know. I don't even know what to search for in my email. Do you know what she uses so that I could search for it?

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lisa fouladi: Mycotoxins. You know. Would you have it from Rupa? Did you get it from Rupa?

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Lindsay Miller: Yeah, I think it's from Rupa. Okay, there we go here

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lisa fouladi: Search for

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Lindsay Miller: There we go!

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lisa fouladi: So the early test is one of the

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lisa fouladi: better tests to use for testing your home environment.

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Lindsay Miller: Yeah, I got it. I got it. I got it. Here we go. Okay. I'm gonna stop sharing. Sorry. Everybody I feel. Ugh!

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lisa fouladi: No, don't worry.

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Lindsay Miller: Thank you. Okay, here's the myotoxin. And this was, this was a great, great test for me.

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Lindsay Miller: And if I go through there's there's 1 that is very high. If I go through all these, and this is the sterrow

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Lindsay Miller: massion that's the one right here that's very high. If I go through all the results. Everything is in normal range.

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Lindsay Miller: normal range until we get to

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Lindsay Miller: stero this one right here. And as you can see on this page. It's a 6.3 9. Everything else is down here

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lisa fouladi: Okay, okay, all right. So

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lisa fouladi: the what? So so the main thing is, you know, you've done it. You wanna

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lisa fouladi: mold addressing Mold has to do with identifying the source and then getting rid of it from your body. Right? So you've identified you know, mold in your environment. And that needs to be remediated. Probably a professional is needed, you know, for mold remediation. And then then you've done the Mycotoxin testing. This test is a very good one.

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lisa fouladi: I would also encourage you to do some inflammatory markers that will let you know how your body is responding, because Mycotoxins induce inflammation. So in in general, you know you would look at. You know your regular Cbc Cmp, but I would also encourage you to do something called

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lisa fouladi: t gf, beta one. That's the it's a, it's a growth factor and and then there's another one which is in the complement system. C. 4, little a.

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lisa fouladi: So those are 2 that will let you know how much. It's a different ways of looking at information, and those when they're elevated can be associated with mold. So it's you know it's great that all of your markers are you know, are low except for that one. But the genetic. If you've done your genetics, the Hla

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lisa fouladi: Dr. Helps identify people who are susceptible to mold. But you've got to really start by supporting the drainage pathways. Right. So you want to introduce binders to bind the toxins in your gut.

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lisa fouladi: so the natural ones would be activated. Charcoal, bentonite clay. Chlorella is one of my favorite go-tos, and then I can often combine chlorella with

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lisa fouladi: with a binder like the gi detox from it's a bio botanicals. But it's biocidin, you know the same company that does biocidin

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lisa fouladi: that has a mixture of all the different binders in it, and then you also need a master antioxidant like Glutathione, because that will really help quench the free radicals that are created as a result of the mold toxicity. Then, of course, you need to do liver support.

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lisa fouladi: so liver support would be

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lisa fouladi: milk. Thistle. I would. Do. You know, things like dandelion, artichoke peas that would be good milk thistle needs to be in the form of tincture, not in a tea form. You could do tincture or pill, but tincture would be a good idea, and then, of course, you know, something like sweating would be a very like infrared sauna to support toxin excretion.

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lisa fouladi: So those are the kind of

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lisa fouladi: steps to support detoxification pathway. So you've got to, you know. You want to stimulate the release of the

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lisa fouladi: Mycotoxin into your bloodstream. So something like Chlorella would be helpful there and then you want to be able to bind it, and then so sort of the binder the gi detox would work there and then. You want to neutralize the free Radicals. So that's where the glutathione would come in, and then, of course, overall liver support, because the liver has to cope with detoxifying, you know, getting rid of the mold.

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lisa fouladi: So that's the basic way I would approach it. A lot of mold stuff is in in the gut

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lisa fouladi: so I would do a stool test as well.

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lisa fouladi: And we're all exposed to mold

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lisa fouladi: But whether our body reacts or not can be genetically determined, but also can be due to the health of our Gi system.

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lisa fouladi: So I would do a stool test. You can do one also through rupa gi map, or a gi effects with the H. Pylori add-on, if it's a gi effects, and then address any dysbiosis or leaky gut that would be caused by the mycotoxins, and that would also give you an idea of whatever else grows, because it just is going to favor a dysbiosis kind of environment, an inflammatory kind of environment. And then, of course, we need to support with probiotics and

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lisa fouladi: and things like that.

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Lindsay Miller: Tell me, though, my first, st my 1st question is that like there is like, this is the mold test. You know the army's test. And 1st of all.

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lisa fouladi: So.

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Lindsay Miller: Hang mold, which you know actually like. If you, if you look at it, the black mold that we actually call mold, there's only like one spore in the whole house, or

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lisa fouladi: There!

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Lindsay Miller: That I took, which is very, very common and normal. And so all these other things is this really mold is that, you know, like.

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Lindsay Miller: you know, I did a little search on the thing that's high in my body, and it it does come to one of these things. They're connected

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lisa fouladi: I did.

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Lindsay Miller: But there's 3 spores in my bedroom, you know.

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lisa fouladi: Well, the the one that you have is a is a mycotoxin.

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lisa fouladi: produced mainly by the Aspergillus family.

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lisa fouladi: As far as I know it and and so you have aspergillus. There, but it's not really high. And then there's this oral basidum, which these are all different kinds of molds.

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lisa fouladi: See, these are fungal ids. So these are all different kinds of molds

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Lindsay Miller: Okay.

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Lindsay Miller: So even mold remediation, which we term mold, they're not shooting just for the black mold they'll be shooting for all of them.

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lisa fouladi: Yeah, I mean, I don't think that their remediation is specific to one variety of mold, but you have this, and you can see what you have at the high counts, and so they will. You know. Obviously, at least, you can recheck. See if it was effective right

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Lindsay Miller: Yeah. And then my next question is, I mean all these things with like the binders which I'll go over in a second, I mean? Is it really even helpful when you're triggered? And you know, having this in the environment, I mean, is it? Is it like remediation first, st and then detox like is that? Is it even worth it to do these when I'm in this home that I you know I can't leave at this moment

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lisa fouladi: I think you. I think you've got to do both.

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lisa fouladi: So you can start by making sure that the elimination pathways are working, that you're having daily stool. You know your daily bowel movements. You can do the sweating and saunas and things like that, and the liver support

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lisa fouladi: and then and then I think at the same time, when you address the remediation in your house, then you can start, but you need to pull it from your body. Anyway. I mean, you're gonna have continual exposure.

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lisa fouladi: So you could just be on a low dose of Chlorella, for example. And a binder to make to get it out of your body, because you need to get rid of what's in your body. But that's not going to stop the re for lack of a better word. Reinfection, you know.

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lisa fouladi: re-exposure. It's not infection, but re-exposure. So yes, I mean, it makes sense. You just got to really get your body in the best shape possible, and do the liver support the milk, thistle and the dandelion, and and all of that

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Lindsay Miller: Okay, great. Let me just go over that. And I have Chlorella in my cupboard. I started it, but I was having a hard time figuring out like when to take it, because it needs to be like 2 h away from food. But that's usually at night, which

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Lindsay Miller: actually gives me a little energy, so I couldn't figure out exactly when to take it

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lisa fouladi: Well.

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lisa fouladi: yeah, I mean, it's well, it's strange. Well, it has a little bit of iron in it, I guess.

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lisa fouladi: I guess timing does matter with with chlorella especially when you're using it as a binder. But you need to be an empty stomach is ideal. If you can cope with it on an empty stomach, so it would be 30 to 60 min before a meal or 2 h after a meal

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Lindsay Miller: Okay, so.

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lisa fouladi: Sorry, what

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Lindsay Miller: You mix it with the gi detox from biotanicals.

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lisa fouladi: Excuse me, I have to do something here. Well, yeah, you just need to take that a different time of day. As well, yeah, because they will bind each other up.

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lisa fouladi: Yeah.

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Lindsay Miller: Okay.

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lisa fouladi: You need to take away from any other medications and supplements. I would just start on the Chlorella

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Lindsay Miller: Okay, great. And then the Bio tentacles add later, I do have ion. Oh, there, Buddy, thank you.

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Lindsay Miller: That's great. Thank you. Thank you. Lori?

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Lindsay Miller: yeah, okay, great. And then I do have glutathione that I can. Just. It's a sublingual. I can just start taking right now. And then some milk thistle I mean, I know about the Benetone clay and the

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lisa fouladi: But tonight, Clay, I mean the the cell core products are very strong. I wouldn't start there. They're very, very strong

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Lindsay Miller: Really strong.

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lisa fouladi: The cell core products that Laurie just recommended. They're very, very strong. So I would just start really gently and so like with the chlorella, and then and then go go from there. I mean, I'm not against cell core. I just know that they are very strong and I don't normally start with them

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Lindsay Miller: Great. Okay? So it's like you can. I can also work my way up. I also think something when the remediation is kind of like done. Then you can kind of

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Lindsay Miller: of handy a little bit harder

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lisa fouladi: Yeah, yeah. Yeah.

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lisa fouladi: But you need to start low, like 500 milligrams to one gram daily of the chlorella. And then you can ramp up. You really need to go up to 3 to 5 grams a day if tolerated. And then, if you're taking high doses, you need to split it into, you know, 2 different times a day.

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Lindsay Miller: Rice. Okay.

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lisa fouladi: I mean the biotics. Research is a good chlorella, and then you really need to hydrate well, because the chlorella needs water to move toxins out

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lisa fouladi: And then you've got to watch out for any die-off symptoms. That's why you got to really start slow. So fatigue, you know. Headache nausea slow down the dose and support detoxification more, you know, if you start to have die-off symptoms, so that's glutathione, and then the binders will help there.

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lisa fouladi: and any kind of sauna

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Lindsay Miller: Okay, probably. Dry brushing, too.

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lisa fouladi: Yeah.

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Lindsay Miller: Okay, so start slow with the with the chlorella. Move up

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Lindsay Miller: At a binder, which is the gi detox

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Lindsay Miller: And and then add the milk thistle in the evening, and some glutathione also. You can do a stool test. I did do a C for lower A, and it's normal

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lisa fouladi: Okay.

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Lindsay Miller: I can't find that there is searched for 2 things which was the C. 4, little a. And they were very normal in normal range, but I couldn't

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lisa fouladi: Well, that's good.

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lisa fouladi: but that's good, that it's normal. And then the Tgf beta, one is also a growth factor. In fact, I mean a marker of inflammation. So sometimes they'll pop up positive when nothing else pops up positive to let you know that there's sort of chronic low-grade systemic inflammation going on

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Lindsay Miller: Okay, okay? And what's that test called

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lisa fouladi: Tgf, beta one, and I'm just gonna tell you what it stands for. Pdf.

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Lindsay Miller: He isn't like Mom. I can't hear it. For some reason

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lisa fouladi: It's p, PG, transforming growth factor, beta, one transforming growth factor.

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lisa fouladi: So it's tgf beta, one

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Lindsay Miller: Yeah, okay, great.

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Lindsay Miller: Okay? So the the big answer question for me was like, Do I do this before remediation? And the answer is, yes, keep supporting the Detox pathways, even though they're still being bombarded and remediation, and then kind of step it up a little bit

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lisa fouladi: Yeah, yeah, absolutely. And follow up with a stool test and see, you know how your

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lisa fouladi: gi tract is doing

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Lindsay Miller: Okay, great.

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Lindsay Miller: Thank you very much.

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lisa fouladi: Okay, no, that's great. So there were no as there were no cases, submitted. Anybody who has test results that you'd like me to review just on the fly. I mean, you know I'm happy to go over them with you. If you have any questions, just

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lisa fouladi: raise your hand, or or just let me know you have a question.

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lisa fouladi: Does anybody have a question or anything? They want to discuss?

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lisa fouladi: Rob

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Rob Vanderwal: I, yeah, I actually have a a Dutch Dutch report that I'd love for you to review. I I just didn't submit it because I haven't analyzed it myself very closely yet, so

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lisa fouladi: Okay, just let's let's go through it together.

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Rob Vanderwal: Okay. Great.

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Rob Vanderwal: Okay. Let me.

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Rob Vanderwal: You see it.

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lisa fouladi: Yeah, we can make it a little bit bigger, so we can see it.

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lisa fouladi: Oh, but on the side, on the right hand or on the yeah on there, you just kind of

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lisa fouladi: there you go.

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lisa fouladi: Yeah, that's that's good.

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Rob Vanderwal: Okay, so is this a female 57 year old? Female?

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Rob Vanderwal: Yeah.

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lisa fouladi: Okay?

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lisa fouladi: So what is the 1st thing that you see on the hormone testing summary

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Rob Vanderwal: Well, the progesterone is

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lisa fouladi: Yeah, and stridial. E, 2 is low, so is she on project. Is she taking Progesterone

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Rob Vanderwal: I don't think so. No.

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lisa fouladi: Maybe she might be taking cream. Yeah, some cream.

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lisa fouladi: Yeah.

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Rob Vanderwal: So, maybe yeah.

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lisa fouladi: It would be unlikely to have the progesterone so high without some kind of supplementation. So

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lisa fouladi: yeah, so she has a cream.

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lisa fouladi: Okay?

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lisa fouladi: All right, and but she's not taking any estrogen

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Rob Vanderwal: Not that I know of no

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lisa fouladi: Okay.

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lisa fouladi: alright. And is she doing an over the counter cream? Because you can buy over the counter progesterone creams

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Rob Vanderwal: I wanna say she's probably got she's she's working with us

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Rob Vanderwal: a naturopathic doctor right now on this. So she probably got a prescription

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lisa fouladi: Okay, okay, all right, because there are over the counter creams as well. But yeah, she needs to discuss the dose with her with her, Doc.

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lisa fouladi: Alright. So you can scroll down. So this is the Dutch, the Dutch complete right? It's not the one. It's not the Dutch plus, is it?

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Rob Vanderwal: It's just a.com

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lisa fouladi: Delete

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Rob Vanderwal: It's complete. Yeah.

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lisa fouladi: Okay, so so the 1st thing, do you want me to take you through it? Or do you want to take me through it?

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Rob Vanderwal: No, I'd rather you do it, because I haven't had time to analyze it myself.

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lisa fouladi: Okay. So I'll just tell you what I do if that's helpful. So the 1st thing I do is I look at the overall pattern. So it picked up. That Progesterone is very high. So I know to ask the client about. You know hormone replacement, or where the source of Progesterone is, you know, obtained. Then I look at the free cortisol pattern. That's the amount of cortisol that's available.

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lisa fouladi: and it's following the lower range moment. In fact, the waking one is just close to the I mean, that's following the lower range limit. But you'll look at the metabolized cortisol, which is total cortisol production is quite high.

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lisa fouladi: but the available cortisol, which is a saliva cortisol is very low. This is a discordant pattern, and that means that she has a lot of cortisol, but the body's clearing it very fast, getting rid of it very fast. It's a clearance issue. It's not a cortisol issue, but even though she's making a lot of cortisol. She'll have symptoms of low cortisol, because the body's getting rid of it very fast.

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lisa fouladi: Usually the top causes for that are overweight, insulin resistance? Is she overweight?

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lisa fouladi: Do you know

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Rob Vanderwal: Yes, yes, yes, slightly.

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lisa fouladi: Okay, so insulin resistance and overweight are tend to be the top reasons. For that.

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lisa fouladi: So, as I said, it's a clearance issue, and if you want to do any kind of support, you can't do anything that raises or lowers cortisol. But you can give general adaptogens. But actually, if you take a root cause, approach, it would be to balance blood sugar. Address the you know Dysglycemia, I suppose, that there is dysglycemia. We look at her diet.

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lisa fouladi: You know. See how many carbs she has in her diet, how much protein, how much fat and and then help with any kind of you know, weight management.

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lisa fouladi: So that would be the way to address that. And then, when we want to look to see about cortisol in relation to bhea. So hormones are all about how they relate to each other. There's always what we call a dance of the hormones, and cortisol is a metabolic hormone. That means it breaks things down.

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lisa fouladi: and when cortisol goes up, if the Hpa axis is functioning properly, Dhea, which is a anabolic hormone, should go up as well to compensate for the catabolic effect of cortisol. So dhea is an anabolic hormone. It means it will offset the breakdown process that the cortisol causes. But you'll see that Dhea is actually rather low. So

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lisa fouladi: this means this person has had stress for a very long period of time, and even though she's making a lot of cortisol. The dhea is unable to compensate. That means the Hpa. Access isn't able to work as it's meant to. So the Hpa access really is

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lisa fouladi: telling us about the stress response. And she is really on. She has a dysregulated or on yeah dysregulated stress response. Basically and and she, it's that. That's how we speak about it. In. In today's parlance, we used to talk about

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lisa fouladi: you know, adrenal stage one stage 2 stage 3 kind of thing that would allow us to kind of categorize it, based on where cortisol is, where dhea is? But it's not really. How can I say there isn't research to back that up. But we can talk about Hpa access dysfunction. So this is really indicative of longer term stress

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lisa fouladi: and and and she will have symptoms of low energy. So questions to ask her would be, how much energy she has on a scale of 0 to 10. What is her morning energy like? Does she have any energy? Low points? And and you know and take it, take it from there, I mean, does she, why did you order a Dutch test for her

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Rob Vanderwal: Yeah. So this is actually her second one and and her second one is, it's almost identical to her 1st one, I mean same cortisol pattern, but she also. But she knows she. So I've asked her these questions, and she does not. She does not feel like she's under stress. She's got plenty of energy. So she's really confused with this, because, you know, the low cortisol is just like what

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Rob Vanderwal: I I feel fine. I'm not stressed, you know. I don't know what the deal is

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lisa fouladi: Does she work, or does she have a family or

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Rob Vanderwal: She? She's she's married but she she does not. She does not work.

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Rob Vanderwal: So that's partly why the reason why she's doesn't feel stressed. You know. She's

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Rob Vanderwal: she's pretty much free to do whatever she wants, and she but she's very active, you know. She goes to. She goes to Yoga with me 3 3 times a week, and

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Rob Vanderwal: So it's just kind of baffling, and she is. She is starting to lose some weight. But yeah, I think she did have some glucose fast. Her fasting glucose was high.

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Rob Vanderwal: so I would

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lisa fouladi: Get a glucose I mean glucose panel on her I mean some people.

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lisa fouladi: You know. They've adjusted to this way of life and and and I guess the way to talk to her about it is to improve her resiliency, you know. So she has a certain amount of stress in her life that's normal for her. She doesn't feel stressed. But these test results

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lisa fouladi: basically show us that she's not very resilient. So you want to increase her stress resiliency. The how her body responds to stressors. Right? So if she does have a major calamity happen in her life here, her body will not just, you know, collapse, basically. So in order to improve her resiliency, you need to talk about you know how much sleep she gets. And and recovery is very important.

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lisa fouladi: That's where these devices, like the Aura Ring or the Fitbit, or the Google Watch. Sorry the Apple Watch, or there's Google watch as well. Are good things. These wearable things because they give an idea about the recovery rate. You know, people don't really give themselves enough time to to recover.

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lisa fouladi: and it looks at heart rate variability. And I think I've probably mentioned I work a lot with corporate clients, and they tend to be bankers, and they're all sort of very, very driven. So they they drive themselves quite hard during the week, and then on weekends. They are likely to be doing like triathlons and things like that. So they basically have no downtime. And so getting people like that to rest when they are just used to pushing through

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lisa fouladi: is very hard, and so we work a lot with them, regarding heart rate variability and getting them to understand that recovery is just as important as pushing, you know, in order to get the body to to recover, so you could encourage her to get some kind of aura ring and

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lisa fouladi: or a well, I have what I wear. It's just a fitbit. It's not expensive, and it just helps me track my heart rate and it has a the. I don't know what it's called on the apple watch, but they have a readiness score. So you kind of know. Okay, on this day. I really shouldn't do cardiovascular exercise, or maybe should just do gentle walking things like that. So it helps people

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lisa fouladi: how to adapt their exercise of the day according to their body's metric. So that would be a good thing. To do.

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lisa fouladi: Alright, you can keep scrolling down.

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lisa fouladi: Okay, let's go to the estrogens.

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lisa fouladi: So first, st before you go there, I always check in terms of the androgens dht, which is the most potent of the androgens and and for women, if dht is high, they'll have an androgenic kind of symptoms, which would be, you know, growing hair, you know, on their face, or you know, losing hair on their head. So her dht is is okay? All right. So keep keep scrolling down.

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lisa fouladi: All right. So yeah, right there. Okay, so 1st thing we're gonna look at is on the left hand side. Dheas in relation to their metabolites. So

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lisa fouladi: dhea, when it's floating around in the bloodstream isn't used like Dhea, it has to be sulfated. So then we have this Dheas. So remember, in the beginning Dhea was quite low. Well, Dheas is a little bit higher.

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lisa fouladi: and because it's a sulfated form of of the of the hormone, it tells us something about the sulfation pathway. So sulfation is one of the 3 pathways that detoxifies hormones. So the pathways are methylation, sulfation and glucuronidation. We can't see glucuronidation on the

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lisa fouladi: Dutch test but we can see it on the stool tests when we look at Beta Glucuronidase.

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lisa fouladi: And or if you, for example, look at Belly Rubin on the blood work, if that's high, that can give you an idea about the Ugt gene which is also involved in glucuronidation or has an influence on that. But that's aside. So here, in terms of sulfation, we want to look at the downstream metabolites. And basically, we want to see.

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lisa fouladi: you know, are the dials pointing in the same direction. So Dheas is nearly at the middle. But if you look at the metabolites, which are, you know, lower down, they are

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lisa fouladi: quite low, so the metabolites are much lower than the Dheas parent hormone is so that implies there is a block in the Sulfation pathway, and in order to help her clear her hormones. We have to support sulfation. So that would be making sure she has enough. Cruciferous vegetables, basically. So that's you know, sulfation is

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lisa fouladi: part of phase 2 detoxification and it helps remove, as I said, hormones other things as well. But there, there is is

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lisa fouladi: block there. Then, if we look down at the 5 alpha reductase activity, it's pretty much a 55%, which is good. So I mean, I'm not suggesting that she takes Dhea. But if you were going to suggest taking Dhea, that's the 1st place you would look

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lisa fouladi: to see how androgenic the the you know, her levels are, because if it's high, you wouldn't really, if it's really favoring 5 alpha you really wouldn't want to be giving more dhea into that situation because it's really upregulated. But if she wanted to she would be okay. It would not be contraindicated. But, more importantly, you've got to support

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lisa fouladi: the salvation pathway, and that's really you know, sulfur veggies the cruciferous vegetables. If she can tolerate them, then if we look over to the right and if you can scroll down a little bit so we can see the whole thing

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lisa fouladi: keep going. Okay, all right. So so e, 1 e. 2 and E. 3 are the 3 types of estrogens, e 2. Estradiol being the most potent of the estrogens, and they are all low, so I guess she's in menopause. Is that right? She's in menopause.

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Rob Vanderwal: Yeah.

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lisa fouladi: Okay. So she's not menstruating any longer. So she's they all in the in, you know, even though women are no longer menstruating, estrogen is still produced by the fat cells

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lisa fouladi: and by the adrenals in small quantities. That's why we really need to take care of the adrenals, especially, you know, in the pre menopausal and during reproductive years. So it really helps women navigate perimenopause and menopause. So we want to see if there is enough protective

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lisa fouladi: estrogen. So that's s. 3, all which is E. 3. And the way we calculate, that is, it's e 3, divided by the sum of e, 1 and E. 2. So let me just calculate that. So it's calculator.

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lisa fouladi: So it's I mean, I can tell you she doesn't have enough E 3 without calculating it, but I'm going to calculate it. It's point 6, divided by 3.2 6,

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lisa fouladi: and it's giving us point 1 6 6. So greater than one is what we're looking for. So obviously, it's

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lisa fouladi: when we, you know, I mean, I didn't have to calculate it to tell you that the answer is going to be less than one. But the just to tell you how to calculate it. So it's it's e 3

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lisa fouladi: divided by the sum of e 1 plus e, 2. Okay, so that's the the formula.

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lisa fouladi: Here, I'll type it into the chat.

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lisa fouladi: It's e 3.

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lisa fouladi: Oh, I can't.

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lisa fouladi: E, yeah. E, 3, divided by the sum of you need one plus 2.

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lisa fouladi: So that's the the formula. And we always or I always calculate that to give an idea? If you know, I mean, the question is, does she want to just take some over the counter? You know you can get quicksilver scientific. They have. You know. Over the counter. Kind of

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lisa fouladi: E 3. Well, it's e 3 and E 2, I guess.

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lisa fouladi: All right? So the estrogens are low. So the same thing here we want to look at the

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lisa fouladi: the downstream metabolites. To see you know what's happening with them. So the we're interested in the total estrogens.

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lisa fouladi: But we're more interested in the ultimate biological action of the estrogens is in their biological effect of the estrogens is how it's metabolized. So that's what we're looking for here. So the protective one is 2. 0, and you'll see the majority of her estrogens are the 2 ohs, it's great. It's 92.3%

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lisa fouladi: and and then the we want to see. You know how much of the estrogens are being metabolized in the you know the the one that is the sort of quote bad pathway, which is a 4 0, 8. So it's 6%, which is

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lisa fouladi: good. It's well below the, you know, estimated range. So I always look at the actual dial itself. So the actual dial is more or less the 4 ohs at the you know Menopausal range, maybe at the upper end of it. But in general she has the majority of her estrogens are the good ones.

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lisa fouladi: The 2 ohs! And the 4 ohs are mercifully low, the 16 ohs! Which can have a duality to them if they're too high. So above this 30%, they would be considered proliferative. And we don't want anything that's proliferative. So what do you associate with proliferation? You know cancer, right? So we don't want anything promotes proliferation.

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lisa fouladi: But at 1.8 8% they're very low and that can have a negative impact on bone health. So I would follow up with.

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lisa fouladi: you know, either asking if she's done a dexa scan, or do or measure bone turnover markers, and then, of course, if she doesn't want to do the bone turnover markers, you could just do a basic Cbc Cmp and look at her acid alkaline balance. So bone. Health is very dependent on acid alkaline balance, so that would be something we could discuss with her there.

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lisa fouladi: So this the 16 0, 4 0, and the 2 ohs! These are all part of phase, one detoxification and then so we pay we need to pay close attention to the percentages right? And we want to see is estrogen metabolizing. Is it favoring, you know, the good estrogens or the quote

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lisa fouladi: unfavorable estrogens? And and she her the way they're being metabolized. It's favoring the 2 0, h's! Which are good, which is protective.

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lisa fouladi: And then we want to look at the bottom here, which the Comt and the Comp and Methylation. This is the sort of phase 2. Detoxification. So I mentioned sulfation is a pathway that detoxifies hormones. So methylation is the other one.

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lisa fouladi: and you'll see that her methylation activity is very low. So you need to support her methylation activity. She's hypomethylating. And so you've got to think about this in terms of the whole goal is to get to the 2 methoxy, one there and and to be able to get rid of the estrogen. So whether

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lisa fouladi: you know the person is taking hormones or the body is making hormones. You were interested in how they're being metabolized, and then how well, they're being excreted from the body, and in her case they're not being excreted. Well, and so you really want to open up the drain. So you think about this here in terms of a drain, and we really want to push the detoxification, and that would be Glutathione or Nac.

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lisa fouladi: and so Nac is the precursor to Glutathione, and then we want to support. So that would start with glutathione, really pushing the glutathione or Nac. And then we want to support Comp gene, and that would be magnesium. Specifically, magnesium threonate. So 1st would be glutathione or nac. The second thing would be

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lisa fouladi: neuromag. So magnesium freonate. And then once you've got the magnesium on board. Need some B 6 as well that supports as a cofactor in this process. So even though her estrogen metabolites are great pro Hs. Are the majority. The excretion pathway, this, this detoxification pathway, that is, methylation dependent is blocked.

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lisa fouladi: So she has a block in sulfation, and she has a major block in methylation, and so she'd have difficulty removing the or there'd be some impairments in removing the estrogens, and they might go back into circulation.

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lisa fouladi: So I would suggest that she would. You would need to measure Homocysteine as well in the blood.

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lisa fouladi: and then measure B 12

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lisa fouladi: and folate both serum and Rbc folate. Okay? So you can scroll down. Now we can look at the organic acids.

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lisa fouladi: So just wait a minute before you go there. You can see there that she's yeah, this. Okay? Favoring cortisone metabolite. So this is a systemic preference. And she's cortisone is the inactive form of cortisol. So about 70 or 80% of the cortisol is converted from inactive to active. It's not like we're always making new cortisol. She is

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lisa fouladi: preferring the body. Her body is prefer preferring Cortisone. So her body is actually trying to get her to slow down

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lisa fouladi: and and relax. So it would be really good to get the fitbit, or something like that, just to have an idea of what her recovery is like. So, even though she feels fine. That may be normal for her and and maybe she's just running on, you know, adrenaline, because she's making all this cortisol cortisol. But it's being inactivated, and that's what the body's protecting her somehow. So she's making all this cortisol. But the body is inactivating it

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lisa fouladi: in deactivating the cortisol so you can see here. The free cortisone pattern also is following the cortisol pattern, but the body is

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lisa fouladi: pretty much deactivating it. So there is a reason for that. So you've got to kind of search for inflammation or something like that.

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lisa fouladi: Alright. So you can keep so you can see how much he's making. Yeah, the cortisol, metabolized cortisol but

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Rob Vanderwal: And

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lisa fouladi: The body is deactivating it. That's always a protective mechanism, you know. Our body is there to help us survive?

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lisa fouladi: Alright, so you can go down to the

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lisa fouladi: or the organic acids. So even though methylmalonic acid is within the range, that's a marker for B 12, and so is B. 6, I would probably she probably needs B. 12, and even though the pyroglutamic acid, which is the marker for glutathione, is within this range, you still need to give her glutathione. It just means that you know. You still need to give her glutathione or Nac to help with the detoxification to help that methylation

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lisa fouladi: drainage pathway. But everything else looks pretty good. The neurotransmitters melatonin is at the lower end of the range, so I don't know. You need to ask her about her sleep. How well she sleeps, how easily she falls asleep! If you stay asleep, how many hours she's sleeping

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lisa fouladi: kind of stuff.

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lisa fouladi: and the 8. 0, dg, which is telling us about oxidative stress at the cell, at the DNA level, that's also within range. Nonetheless, I would still support. You know, dietary perspective the the colors to help her have all the phytonutrients.

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lisa fouladi: But at least there isn't any sort of overt DNA damage that's measurable. So this test only measures 8 Ohdg. The Nutraval or the metabolomics will look at lipid peroxides in addition to the 8 0 Dg. Which is looking at the oxidative stress, at the cell membrane level as well.

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lisa fouladi: So do you have any questions

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Rob Vanderwal: Yeah.

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Rob Vanderwal: So I told you. She's working with a naturopathic doctor, and I think that that doctor is going to give her the spectra cell test, which I think is equivalent to the neutral

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lisa fouladi: It's not equivalent. It's not very accurate. I'm very familiar with it, and it's not a replacement for the nutraval

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Rob Vanderwal: Oh, okay.

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lisa fouladi: Yeah, it's not a very good test. It's really not very accurate, I mean, if that's all you've got to work with, then you can work with it. But the nutraval it's not. The nutraval is an organic acid test, and the spectracell. I forget what they're looking at white blood cells, but it gives an idea of of nutrient levels. But I'm not even sure how act. I mean, it's not spectracell

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lisa fouladi: method.

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lisa fouladi: I know that they I know they they think that they are looking at nutrient needs at the cellular level, but they're actually not the best way to look at nutrients at the cellular level. Functional levels is looking at an organic acid test

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Rob Vanderwal: So let's see here,

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lisa fouladi: It's I know they have really good what they talk about. But

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lisa fouladi: I'm just trying to see what they're looking, what they're measuring. They're not measuring organic acids. They may be looking at white blood cells or science. I'm just looking at the

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lisa fouladi: I don't know what their methodology is at the top of my on top of my head, but I have looked into it and looking at the history and technology upset my. It used to be quite popular. But it's looking at.

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lisa fouladi: Okay.

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lisa fouladi: So they say, serum levels are transient. Blah, blah,

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lisa fouladi: still doesn't say, Oh, yeah, it's looking at lymphocytes. That's why I said, white blood cells. Yeah, it's looking at white blood cells. It's really not that accurate.

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lisa fouladi: So, Deborah, do you have a question.

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lisa fouladi: You're muted

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Deborah N: Oh!

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lisa fouladi: You're muted again

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Deborah N: I just wanted to get in the queue after this.

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Deborah N: Okay.

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lisa fouladi: Okay. Alright. Okay. So if I mean, if that's what her doctor is ordering, you can't do anything about it. But you can just help her interpret it

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lisa fouladi: and then try to get her to do a nutrival

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Rob Vanderwal: Yeah, yeah.

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Rob Vanderwal: Okay, yeah. Yeah. You've answered, yeah, all my questions perfectly. So yeah, that's exactly what I want to know.

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lisa fouladi: Okay. Alright!

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Rob Vanderwal: Thank you.

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lisa fouladi: Let us know how she is, and then we give her adaptogens for the if. You say it's a second Dutch test, and it's exactly the same, you know. Help her with the Dysglycemia for sure, insulin resistance, and then also you can give her some adaptogens like Rhodiola, or Holy Basil or Ashwagandha, and then measure her thyroid as well.

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lisa fouladi: because you know, thyroid and adrenal health are very, you know, intermingled

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Rob Vanderwal: Okay. Thank you very much.

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lisa fouladi: Oh, you're welcome, hey? Deborah

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Deborah N: Okay, I have 2 quick questions, and then

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lisa fouladi: I will!

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Deborah N: Wondering if you might. That was so fabulous. I have actually a I'm in the same situation as Rob, where I've looked at the Dutch test, but I haven't really analyzed it myself. If you could walk through it, that'd be great, and it's a Dutch

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Deborah N: plus.

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Deborah N: So maybe it would illustrate the differences, too, between the 2

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lisa fouladi: Yep.

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Deborah N: My 1st question is regarding the one that you just did. If your client has shown reactivity to Nac, like I I think they? I'm trying to remember what the outcome was. I think it was made them anxious.

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Deborah N: I could be mistaken there, but it was some kind of reaction to it is that a sign of something? If they aren't able to take Glutathione or Nac

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lisa fouladi: Oftentimes people who have blocks in their sulfur pathways may not react well to Nac or Glutathione, because both Nac and Glutathione are sulfur amino acids

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lisa fouladi: and and so the thing to do there is to help, you know, evaluate how much sulfur she has in her diet. Or, yeah, I guess it's a female I'm assuming it's a female. But you know a lot of times people think broccoli cauliflower all the cruciferous vegetable cabbage, etc. It's very healthy, and they are, but if they are sulfur pathways are backed up.

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lisa fouladi: then they can't really process the sulfur. So the remedy for that is to go on a low sulfur diet 2 to 4 weeks. And it's mostly the

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lisa fouladi: red meats which are very high in the sulfur amino acids. You basically would recommend a plant-based diet, but low amounts of broccoli, cauliflower, and all that. Some fish is okay. No dairy dairy is very high in the sulfur amino acids and no eggs, no cheese.

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lisa fouladi: I mean, I said no dairy, but no eggs as well, because eggs are very high in sulfur, so that's the 1st thing to do, and then to help clear the sulfur molybdenum, which is a mineral, is very helpful.

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lisa fouladi: So 150 micrograms like twice a day.

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lisa fouladi: and then a specific form of B, 12, called hydroxy. B, 12 also helps clear the sulfur

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lisa fouladi: and and then you can. I mean, so yeah, that's where I would start, and then and then you can. If they cannot take Nac. Or Glutathione, you can often then get away with giving glycine, which is one of the building blocks of glutathione. Glycine is not a sulfur amino acid

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lisa fouladi: and and glycine is quite helpful for detoxification.

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Deborah N: Okay, thank you so much. That's perfect. That's a very complete answer. Okay, the next question is actually on something different. If we had time to go into a blood test after I just received a blood test

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Deborah N: on a 20 year old girl, a young woman, and her vitamin D was at 18.6

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lisa fouladi: Would be efficient. Yeah, yeah, yeah.

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Deborah N: Yes, very

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lisa fouladi: Yeah, yeah.

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Deborah N: Yes, and so my question is,

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Deborah N: Her doctor originally put her on a combo product of d. 3 K. 2,

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lisa fouladi: Okay.

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Deborah N: If you're really trying to elevate the d. 3,

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Deborah N: what is the is there a safe ratio? Do you always do it in the same ratio, even though you're you might be giving them

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Deborah N: high high levels of D 3

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lisa fouladi: I would say you could continue with the d. 3 k. 2. But then do a separate d. 3. Supplement like at 5,000 Ius, and then retest it in in 3 months time, because vitamin d is toxic at high levels, and then other thing to test is something called palcitriol, which is a different form of of of vitamin d. It's 1, 25

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lisa fouladi: instead of the normal. D. 3 that is checked in the blood is 25 0, 8. So that's the normal one. That's the one that you, you know said it was 18. But the calcitriol lets us know about vitamin d metabolism.

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lisa fouladi: and if that is deficient too, then she's really really deficient. But if that is okay, then you can get away with. Then you know that you know, you've got to get her levels up, that you don't have to be quite as aggressive. And that also lets me monitor people who may have optimal levels of D 3,

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lisa fouladi: but this may be high, so they need to moderate how much d 3 they're taking. It really lets us monitor. You know, supplementation, I guess, in a good way, because so many people are obsessed with taking these 3. And really the hyper vitaminosis D is A is a real thing. People are taking too much

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Deborah N: So, okay.

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lisa fouladi: And it's and so

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Deborah N: Awesome.

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lisa fouladi: Calcitriol it's called calcitriol. It's kind of expensive, but it's it's worth measuring. It's it's called calcitriol, or 1 25. 0, 8. Yeah.

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Deborah N: Okay? And then, so what would be then? So she would just take the K 2 at at what level

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lisa fouladi: Well, if she's taking a combined, if she's taking the com, I would continue taking the combined d. 3 k. 2, whatever the dose is there, and then add a separate d 3 like at around 5,000. I use daily

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Deborah N: Okay, got it perfect. Okay, may I share? Is somebody else?

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lisa fouladi: Share your screen? Yeah.

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Deborah N: Okay, I have never done a screen share before, so we'll give it a go

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lisa fouladi: Hey, justina just press screen, share

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Deborah N: I press, screen, share. Now, what what do I

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lisa fouladi: It'll show you some screens. So select the screen that that has your blood tests on it.

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Deborah N: Oh, okay. Oh, gosh, I'm looking for it.

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Deborah N: Oh, here it is. Right there. Okay, this is actually the Dutch plus.

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Deborah N: Okay, well, okay, there we go.

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lisa fouladi: Right.

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Deborah N: Good, good.

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lisa fouladi: Okay, this is the Dutch cost. That's right.

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lisa fouladi: Okay? So all right, you can scroll down.

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lisa fouladi: Oh, okay. So the difference between the Dutch and the excuse me, the Dutch and the Dutch plus is

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lisa fouladi: The Dutch class looks at the cortisol awakening response. And and

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lisa fouladi: oh, my I'm sorry, fairly low. So the cortisol awakening it's it's very, very low. So the cortisol awakening response is

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lisa fouladi: responsible for producing about 50% of the cortisol available for that day, and we want to see is that the waking level is within the range, but at the lower end of the range, and then waking, plus 30 should be the highest point, that there should be a robust response. And then waking, plus 60 should be lower than

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lisa fouladi: the waking, plus 30, but not as low as the waking, and then it should go down from there. So this is really a good example of a very underactive cortisol awakening response. The waking level is higher than the waking plus 30 and and then it goes down from there. So she has an inverted Circadian rhythm, because then cortisol site starts to go up later on in the day

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Deborah N: This is a mail, by the way.

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lisa fouladi: Oh, it's a oh, it's a male. Okay? Well, the the man, then, yeah, and so

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lisa fouladi: yeah. So it's a very, very underactive cortisol response. So that will be associated with very low energy. And we've got to really speak to. I mean, you want to have cortisol cortisol. The difference between the urinary sample that we saw previously. And this is this sample with a you know, the salivary sample is, it tells you about cortisol in that moment, in time.

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Deborah N: And then

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lisa fouladi: It's like a moving moving picture as opposed to, you know, a photograph which is a, you know, just still and so this person really isn't, I mean. So the if we look over and metabolize cortisol

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lisa fouladi: the person is making cortisol. But the available cortisol is very, very low. So the 1st thing you've got to do is try to encourage cortisol production in the morning.

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lisa fouladi: and that would be having something like a light box to, you know, in order to get some light onto the retinas to get the cortisol to be produced, because not producing much cortisol in the morning, or at all. And I would say a light box. 20 min a day would be a good idea. You can get a light box, Amazon, or wherever and they're very inexpensive. They're about 20 to $30

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lisa fouladi: and it should have 10,000 lux. That is the sort of criteria. You don't look directly in it like you wouldn't look directly in the sun, but you have it on for 20 min

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lisa fouladi: every morning, and of course. You know, getting out in the daylight is very important, but really, at the morning, as soon as. So that's how our cortisol is produced. As soon as light hits the retina. When we start to wake up. That's when cortisol you know, is is produced. That's the stimulus. So the cortisol. Awakening response is,

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lisa fouladi: is the 1st I, you know, gives us the 1st inclination of how the stress response. The Hpa access is working and it's not working. So there's

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lisa fouladi: It's very down regulated. Let's put it like that. The HP access is down regulated, but in the afternoon it's going up, and then in the evening, so I don't know. This person looks like a night owl, and they're getting their energy at night.

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Deborah N: Okay, may I comment here.

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lisa fouladi: Yeah.

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Deborah N: Okay. So this person is,

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Deborah N: is actually is working with a doctor in Arizona, lives in California, but is working with an Arizona doctor who has put a a pump

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Deborah N: actually attach the pump to him and it. They're using it for cortisol. It's a cortisol pump, I guess.

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Deborah N: And they said

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lisa fouladi: Does he have Addison? Does he have Addison's, or what? Why does he have Cortis

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Deborah N: He's well, they apparently his. He has no cortisol

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lisa fouladi: So he has Addison's. So he has. Addison's disease. Is that right? He said. Autoimmune disease with Addison's

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Deborah N: You know what I have asked him that, and they have not specifically diagnosed that. So I don't know if he's just not not picking. He's not remembering that they did that, but I asked him that directly, and he said that

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Deborah N: no

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lisa fouladi: If he has a cortisol pump and the doctor is giving him cortisol. It's usually in relation to not producing cortisol, and they would have tested it, and I don't. I mean, I can't diagnose I'm not a doctor, but it's usually something like Addison's, which is actually, usually we talk about Hpa access dysfunction. That's actual. There are 2 diseases that are associated with the

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lisa fouladi: the adrenals. One is Cushing's and the other one is Addison's, and they're both autoimmune diseases, so does he have any kind of diabetes, or anything like that.

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Deborah N: No, he does not. He was wearing a Cgm. For a short period of time, but it didn't really elicit that information. I mean it, didn't he? His! It wasn't elevated. It would go up and down. But it was. It definitely wasn't in the diabetic.

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Deborah N: He wasn't having serious spikes. We adjusted his diet and everything, you know, sort it out

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lisa fouladi: I have seen flatlined cortisol before. This is not. It's nearly flatline, you know, in the beginning, but it's not flatline, because he's making cortisol. And that's usually when people have, like primary or secondary adrenal failure, right? And so they would be. It would be. In that case I would refer to a medical doctor, so he's working with a medical doctor or a naturopath. What kind of Doctor

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Deborah N: He's working with them. He's working with a medical doctor, but he actually sought me out. He sought me out for the other things that I do in my practice and because he doesn't feel that the medical doctor is really getting to the crux of what's going on. They've got this he, this, these levels are with the pump.

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Deborah N: And so the

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lisa fouladi: Okay.

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Deborah N: Been. They have said it. They brought him in. He was in there. He was in Arizona for 5 days, and basically they didn't do, and it didn't sounded like they didn't do any specific testing. They would just bring him in. They put the pump on. They would bring him in in order to set the program, I should say, and so they would bring him in. They would say, How did you? How do you feel today?

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Deborah N: Them? What happened, you know, the day before, and then they would adjust it, and then they would. He would come back the next day they would ask him the same thing. They would, they would tweak the program so that there's they actually can dial it in like a computer program. So that at a certain point in time. It gives him so much

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Deborah N: cortisol, and then, you know, it's they can

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lisa fouladi: Well.

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Deborah N: Actually put a program. Okay.

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lisa fouladi: Well, he's he needs it in, I mean, if you're gonna discuss it with him, he needs it in the morning and not in the afternoon. So

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Deborah N: Okay.

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lisa fouladi: All right, so you can keep so. And this person as well has a discordant pattern. He's making cortisol. But there's not a lot of cortisol available.

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lisa fouladi: That's also an example of fast clearance, and there is very low dhea. So the you know his his Hpa access cannot compensate for the for the elevation in cortisol, and he's had sort of long term stress. But I guess

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lisa fouladi: he has some kind of adrenal failure, right? If he's being medically treated with cortisol, I mean with I mean, those are horrible terms to use. But in those situations. You know, hormone replacement, which is what he's getting is not inappropriate as long as it's medically supervised.

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lisa fouladi: Okay, you can scroll down. But I mean, you discuss with him. He needs to have more of a dose in the morning. I mean, he needs to discuss the dosing with his doctor. Okay, okay. So okay. So all his androgens are low. Alright! Let's just go down to the to the pictures, to the graphs. You can go down

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lisa fouladi: all right. So like we were talking with to rob. We can look at the sulfation pathway. Here we look at Dheas in relation to the metabolites, and that one metabolite is low, but the other one is not low, so the sulfation pathway isn't working well. So is this the same person that can't deal with the Nac and glutathione

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Deborah N: No different person.

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lisa fouladi: Okay, all right. So cruciferous vegetables would be the remedy there. And dht, is the way. Yeah. So for men, the graph looks a little bit different. Dht, which is the most potent of the androgens, is very low. And yeah, and but he's is he taking testosterone? Is he being given testosterone

435
01:07:56.220 --> 01:07:56.800
Deborah N: No.

436
01:07:57.280 --> 01:07:58.760
lisa fouladi: Okay? All right.

437
01:07:59.520 --> 01:08:08.569
lisa fouladi: So he has low androgens in general, although he does have some testosterone. You can scroll down. Let's look at the estrogens.

438
01:08:09.210 --> 01:08:12.400
lisa fouladi: So men can also have issues with

439
01:08:12.450 --> 01:08:30.810
lisa fouladi: 4 ohs, and can have a you know, cancer risk. So his 4 ohs are. Just. Look how high the 4 ohs are on the range. So even though the estrogens are so, 4 ohs are the quote bad metabolites.

440
01:08:30.810 --> 01:08:57.599
lisa fouladi: And as a percentage of the total they're above the range. But if you look here, look at the estrogens. The estrogens are all low, but the 4 0, metabolized is a breakdown process. He's making a lot. He's making something from nothing. Basically. So there's a really want to pull out these 4 ohs, and there would, I would suggest, calcium deglucarate would be very important.

441
01:08:58.025 --> 01:09:10.360
lisa fouladi: And you know, even a combination of dim and calcium deglucorate to help pull out these 4 ohs! These are hydroxy. You know, these are really

442
01:09:10.500 --> 01:09:13.166
lisa fouladi: we don't want them to be so high.

443
01:09:13.720 --> 01:09:32.720
lisa fouladi: And the 16 ohs are on the lower side. He has some 2 ohs! But you really want to from a dietary perspective, it would be promoting the 2 ohs and lowering the 4 ohs! So those are the cruciferous vegetables, flax, seeds.

444
01:09:33.050 --> 01:10:01.840
lisa fouladi: Rosemary is really good, the herb it promotes the formation of the protective 2 ohs, you can, you know, sprinkle that on vegetables, make a rosemary tea, and then, of course, the Omega. 3 fatty acids are really important. They increase the 2 ohs! And they help decrease the 4 ohs! So we just want to kind of push the 2 ohs even higher, and reduce the 4 ohs, and

445
01:10:02.180 --> 01:10:18.978
lisa fouladi: and really think aggressively about calcium dglucurate and dim, would be good to do a stool test as well, to look at Beta Glucuronidase to see what that is doing. But

446
01:10:19.970 --> 01:10:23.519
lisa fouladi: yeah, these 4 0, 8 s. Are troublingly high.

447
01:10:24.049 --> 01:10:41.359
lisa fouladi: And then, if we look, if you can scroll down a little bit, we look at at the methylation pathway. He has a higher methylation, activity. He may almost be hyper methylating. You better make sure he's not on any kind of methyl nutrients like methyl b, 12 or methyl folate.

448
01:10:41.420 --> 01:10:53.270
lisa fouladi: And here again, we need to calm down this methylation pathway. So neuromag would be important. So, generally speaking, if we look at the 2 ohs, and then the 2 methoxy.

449
01:10:53.651 --> 01:11:15.820
lisa fouladi: We want the that to be about. You know. Give us an idea of how well he's able to get rid of the the estrogens, and it's just the 2. Methoxy is too high. So neuromag would be the remedy there and be 6 and make sure that he's off of any kind of methyl. B. 12 and methyl folate

450
01:11:15.820 --> 01:11:33.599
lisa fouladi: b. 12 would be okay, but but not methyl forms, because just as Rob's person had a hypo or underactive methylation. This person has hyper nearly hyper methylation, so it's working, but it's working

451
01:11:33.730 --> 01:11:51.100
lisa fouladi: too fast. If the cycle is spinning too fast and may have symptoms such as anxiety and sleeplessness, things like that. But the more concerning thing about hypermethylation is, it turns off tumor, suppressor genes, and we never want to turn off tumor suppressor gene.

452
01:11:51.410 --> 01:11:54.949
lisa fouladi: So that's why we're concerned about hypermethylation.

453
01:11:56.580 --> 01:11:57.819
lisa fouladi: Okay, you can scroll down

454
01:11:57.820 --> 01:12:02.000
Deborah N: Turns it turns off tumor, suppressing genes.

455
01:12:02.430 --> 01:12:02.960
lisa fouladi: Yes.

456
01:12:03.780 --> 01:12:06.870
Deborah N: Okay, okay? And you want me to scroll down

457
01:12:07.230 --> 01:12:10.283
lisa fouladi: Okay, you can scroll down all right.

458
01:12:12.950 --> 01:12:35.979
lisa fouladi: so he has some insomnia, right? So we saw that the cortisol going up. So since he's getting cortisol in a pump, really, if he has cortisol in the evening, so usually when everything is working properly, cortisol is higher in the morning, lower in the evening, and as cortisol comes down in the afternoon evening and Melatonin goes up, that's how you know sleep is induced. So if his

459
01:12:35.980 --> 01:12:52.139
lisa fouladi: cortisol is going up in the evening. Of course it's going to be stimulating, and it's going to interfere with his sleep, so we can see with insomnia measurement. It's above the range. So you need to talk to his doctors about giving him the cortisol in the pump earlier in the day and not in the afternoon, where he's getting bumped

460
01:12:52.480 --> 01:12:57.320
lisa fouladi: alright. So You can scroll down a little bit further.

461
01:12:59.150 --> 01:13:28.242
lisa fouladi: It's an art, you know, getting the right dosing. So his systemic preference seems to be okay. It's kind of more or less balanced. But you can see he has. If you look at the patterns, the free cortisol versus the free cortisone pattern. They normally are the same. His is not his is very it's the cortisone is you know. Yeah, the body is deactivating some of that cortisol cortisol.

462
01:13:29.110 --> 01:13:33.390
lisa fouladi: Oh, poor guy, I wonder? Yeah. Well, you can keep keep scrolling down.

463
01:13:34.590 --> 01:13:54.670
lisa fouladi: I had a person who had Addison's and wasn't on a pump, and they gave such a big dose of cortisol that it went up. I'd never seen such a high cortisol response, and then it just came crashing back down. So being on having a pump is much preferable, just being given a big bolus, you know. But

464
01:13:55.050 --> 01:14:19.219
lisa fouladi: yeah, so it needs B 6. The xanthurinate is above the range and so B, 6 is a cofactor in hormone metabolism. So but 1st get the neuromag or the magnesium thuronate on board again, take up to 3 of those a day. So the brand would be designed for health neuromag and basically have it at night. That would help as well with the sleep, and then

465
01:14:19.220 --> 01:14:25.060
lisa fouladi: work up to 3 sort of over time, and then then add in the B. 6, p. 5, p.

466
01:14:26.265 --> 01:14:36.329
lisa fouladi: Indican is above the range, so indican is a marker of dysbiosis. So I would just really follow up with looking at the gut health and do a stool test.

467
01:14:37.700 --> 01:14:41.800
lisa fouladi: especially with those 4. 0, hs, I bet his beta Glucuronidase is high, too.

468
01:14:42.400 --> 01:14:43.309
lisa fouladi: And

469
01:14:44.830 --> 01:14:51.310
lisa fouladi: yeah. So Melatonin, as we would expect is is on the low end of the range because cortisol is jumping up.

470
01:14:55.190 --> 01:14:56.650
lisa fouladi: Did you have a question, Rob?

471
01:14:57.880 --> 01:14:58.430
Rob Vanderwal: Oh!

472
01:14:58.430 --> 01:15:00.870
lisa fouladi: No, okay. Oh, you had to have okay.

473
01:15:01.210 --> 01:15:19.450
lisa fouladi: all right. But the neurotransmitters look balanced and good. I mean, even though pyroglutamic acid, you know the marker, for Glutathione says, within the range, I would say it would not be bad to support him with antioxidants in general, because of having this kind of

474
01:15:19.610 --> 01:15:33.850
lisa fouladi: without without. I don't have a problem, you know. Adrenal failure type of situation, right? I don't know what it is, but it's symptom, you know. If he's if he's been fitted with the pump, he has some kind of adrenal failure, right? Whether it's primary or secondary.

475
01:15:36.270 --> 01:15:42.639
lisa fouladi: and doctors don't give cortisol as replacement. If there isn't, if the body's producing it, so

476
01:15:46.670 --> 01:15:48.540
lisa fouladi: do you have any other questions, Deborah

477
01:15:49.260 --> 01:15:59.349
Deborah N: Actually, I do. So just to follow up on the the neuromag, you said up to 3 a day, and generally at night, so it would not be in divided doses. You would keep it.

478
01:15:59.870 --> 01:16:00.590
Deborah N: Yeah.

479
01:16:00.590 --> 01:16:04.219
lisa fouladi: Can take it during the dose at night would be 3.

480
01:16:04.650 --> 01:16:19.860
lisa fouladi: You take 3 you could also take it during the day. If he has anxiety. I don't know what kind of person it is. He's wired, and then you can take one. In addition to taking it at night. You can take it during the day as well every 4 to 6 h. But just take one.

481
01:16:20.720 --> 01:16:23.400
lisa fouladi: You don't want to have any tiredness. Yeah.

482
01:16:24.200 --> 01:16:32.790
Deborah N: Right. Yes, he actually, he's under a lot of stress, because he is the primary caregiver for his 82 year old. Father

483
01:16:33.260 --> 01:16:33.735
lisa fouladi: Okay.

484
01:16:37.310 --> 01:16:39.539
Deborah N: So that adds a lot of stress

485
01:16:39.920 --> 01:16:41.140
lisa fouladi: Yeah, of course.

486
01:16:42.100 --> 01:16:48.671
Deborah N: Okay, okay, if let's see, you said, oh, you made a comment about

487
01:16:49.810 --> 01:16:54.430
Deborah N: Oh, shoot it was if something.

488
01:16:55.610 --> 01:17:08.240
Deborah N: Oh, gosh! I'm sorry I was trying to take notes as fast as possible. But you just said, with relationship to, I think this part of the test, that if something is

489
01:17:11.740 --> 01:17:14.310
Deborah N: oh, shoot is high! Then

490
01:17:14.600 --> 01:17:19.420
Deborah N: you didn't really say what you would do if it did show up high.

491
01:17:20.160 --> 01:17:22.820
Deborah N: I'm sorry I, in relation to

492
01:17:22.990 --> 01:17:24.539
lisa fouladi: In relation to what

493
01:17:24.980 --> 01:17:27.345
Deborah N: Oh, that's what I can't remember.

494
01:17:28.770 --> 01:17:32.549
Deborah N: Well, maybe it'll

495
01:17:32.550 --> 01:17:33.430
lisa fouladi: Oh, nothing!

496
01:17:33.430 --> 01:17:33.820
Deborah N: And

497
01:17:34.190 --> 01:17:38.509
lisa fouladi: Methylmalonic acid, or the organic acids, or the

498
01:17:38.510 --> 01:17:39.520
Deborah N: It, was it?

499
01:17:39.680 --> 01:17:48.029
Deborah N: Okay? So if no, it was you were you were talking about. The Endicon

500
01:17:48.830 --> 01:17:49.740
lisa fouladi: And it can, yeah.

501
01:17:50.260 --> 01:17:52.680
Deborah N: With a with a stool test

502
01:17:52.680 --> 01:17:58.589
lisa fouladi: Beta beta glucronidase, it still would be the same calcium deglucurate.

503
01:17:58.870 --> 01:18:27.720
lisa fouladi: The root cause would be addressing a dysbiosis. But it's important to bring the Beta Glucronidase down, because what happens is that it impacts the glucronidation pathway. And what happens is that the bacteria end up uncoupling the hormone packages that are meant to be excreted, and they re-release the hormones back into circulation.

504
01:18:28.530 --> 01:18:31.220
Deborah N: Okay, okay.

505
01:18:31.670 --> 01:18:40.247
Deborah N: alright. So great, great, great, perfect, perfect. I'm gonna have to re-listen to this a couple of times. Thank you so much.

506
01:18:40.620 --> 01:18:47.200
lisa fouladi: We will come. But yeah, he needs to be on calcium deglucurate, anyway, because the 4 0 hs are are as high as they are

507
01:18:47.780 --> 01:18:51.849
lisa fouladi: and then you need to retest again in about. You know

508
01:18:51.980 --> 01:18:54.179
lisa fouladi: no more than 6 months from now.

509
01:18:54.530 --> 01:18:56.509
lisa fouladi: See what the metabolites are doing

510
01:18:57.580 --> 01:18:58.490
Deborah N: Okay?

511
01:18:58.870 --> 01:19:03.295
Deborah N: And okay, great.

512
01:19:04.600 --> 01:19:08.469
Deborah N: did someone else have something? Or did you want to try to do the blood test?

513
01:19:09.280 --> 01:19:20.269
lisa fouladi: Well, we have 10 min. So I don't think anybody else has anything. So why don't you just show us the blood test? Is it already in the software, or or it's just a blood test on its own

514
01:19:20.750 --> 01:19:25.006
Deborah N: Oh, you know what? Actually I do. No, I have it in the software.

515
01:19:25.310 --> 01:19:29.690
lisa fouladi: Okay? Well, show me the Odx blood test history. Then

516
01:19:30.110 --> 01:19:32.173
Deborah N: Oh, okay, let me

517
01:19:33.990 --> 01:19:36.420
lisa fouladi: I don't want to see the whole thing. Just the blood test history.

518
01:19:37.540 --> 01:19:40.999
Deborah N: Okay, blood test history. Okay, okay, hold on one second.

519
01:19:41.220 --> 01:19:44.260
Deborah N: Alright. So let me go to her file.

520
01:19:45.340 --> 01:19:47.160
Deborah N: Okay, odx.

521
01:19:47.290 --> 01:19:50.459
Deborah N: Odx. Patient.

522
01:19:51.930 --> 01:19:56.410
Deborah N: Okay, so this should this should be it. But we'll have to scroll

523
01:20:00.980 --> 01:20:05.959
lisa fouladi: Yeah, just go to the table of contents. And then you can click on history.

524
01:20:08.120 --> 01:20:09.989
lisa fouladi: Yeah, yeah, just click on

525
01:20:09.990 --> 01:20:11.229
Deborah N: Even though it's a p.

526
01:20:11.450 --> 01:20:12.580
Deborah N: The Pdf

527
01:20:12.880 --> 01:20:18.049
lisa fouladi: Yeah, it should be clickable. Just go on to blood, test history and click on it.

528
01:20:18.660 --> 01:20:20.520
Deborah N: Where is that number? 6?

529
01:20:20.670 --> 01:20:21.740
lisa fouladi: Number 29,

530
01:20:21.740 --> 01:20:23.159
Deborah N: Straight. 2930.

531
01:20:23.160 --> 01:20:25.709
Deborah N: There, there we go. Okay. Good. Great, thank you.

532
01:20:26.570 --> 01:20:31.519
lisa fouladi: Okay, so glucose, you want me to go through it, or do you want to go through it?

533
01:20:31.860 --> 01:20:34.960
Deborah N: Oh, no! Would you please? Within 10 min I couldn't possibly

534
01:20:35.490 --> 01:20:40.370
lisa fouladi: Okay, so hemoglobin a 1 c is optimal. We don't have a insulin

535
01:20:40.741 --> 01:21:04.429
lisa fouladi: so if he's going to any, follow up testing needs to have an insulin fasting glucose as you'll hear. It's not it says Non. Fasting glucose, anyway. But it's not really a fasting. You're gonna learn that in sweet spot, because the real fasting one is when you take when you when you 1st get up in the morning but so far from what I mean, the a. 1 c is optimal

536
01:21:04.430 --> 01:21:17.770
lisa fouladi: and she needs an insulin, though, to have it complete. The kidney panel kidney function is optimal. Bun is functionally low. So I would look at the amount of protein in the diet

537
01:21:17.820 --> 01:21:38.600
lisa fouladi: and check to see that there's sufficient amount of protein is being, you know, there's sufficient protein intake, and then you can, you know, do that in chronometer or myfitness power, one of those things to see how many grams of protein are being eaten a day, and then you also can look at digestion and absorption of protein in you know, obviously in the stool test.

538
01:21:38.680 --> 01:21:48.509
lisa fouladi: and creatinine is also functionally low. So that would be associated with, you know, muscle loss. So you also need to have a sufficient amount of protein. How old is this person

539
01:21:49.100 --> 01:22:01.621
Deborah N: Okay, she when this test was done, she was 20. It was just it was done in August of last year. If I could just give you if I could just give you a couple of facts about her.

540
01:22:02.490 --> 01:22:11.040
Deborah N: Been really difficult to to kind of wrestle with. She is basically has had candace

541
01:22:11.360 --> 01:22:13.868
Deborah N: syndrome right? So she has

542
01:22:14.370 --> 01:22:16.350
lisa fouladi: What is it? What is it called?

543
01:22:16.920 --> 01:22:19.250
Deborah N: Candace, PAND a s

544
01:22:19.250 --> 01:22:22.320
lisa fouladi: Oh, oh, pandas! Pandas! Okay? Oh, yeah. Okay.

545
01:22:22.320 --> 01:22:25.359
Deborah N: So she is hypersensitive to everything.

546
01:22:25.610 --> 01:22:30.780
Deborah N: Isn't like on sensory overload all the time, can barely leave her bedroom

547
01:22:31.360 --> 01:22:31.659
lisa fouladi: Who and

548
01:22:31.660 --> 01:22:41.979
Deborah N: Fact, can barely leave her bed. She has. We're trying to work on items that she could expand to her diet, you know. She right now is.

549
01:22:42.180 --> 01:23:00.049
Deborah N: She has issues with taste, texture, smell, and it all of these sensory overload things. And it it goes down to her food. So so a lot of foods, the texture! She can't eat it. It sets her sensory

550
01:23:00.480 --> 01:23:08.150
Deborah N: things off so she literally can. She was eating like steak and

551
01:23:08.260 --> 01:23:22.860
Deborah N: carrots, and then she went to like steak and peas, and then the steak she just all of a sudden she was like, I can't even think about steak without not without feeling ill. So now she's eating, and has been eating

552
01:23:23.190 --> 01:23:25.469
Deborah N: these kind protein bars

553
01:23:26.050 --> 01:23:26.740
lisa fouladi: Room.

554
01:23:26.740 --> 01:23:28.420
Deborah N: For several weeks.

555
01:23:28.840 --> 01:23:48.679
Deborah N: and occasionally she'll she'll be able to add like a food in. But the problem is that every time she eats a food she has, I'm going to say, abdominal distress. Well, she has pain, it's not really abdominal. It's a pain that's emanating right at the solar plexus right below

556
01:23:49.180 --> 01:23:49.530
Deborah N: the

557
01:23:49.530 --> 01:23:50.190
lisa fouladi: Oh!

558
01:23:50.520 --> 01:24:00.039
Deborah N: The sternum and or the xifoid process, and she has had so many tests and scans in the medical community, and they can find nothing

559
01:24:00.250 --> 01:24:01.540
Deborah N: nothing shows up.

560
01:24:02.120 --> 01:24:02.955
Deborah N: So

561
01:24:05.130 --> 01:24:18.116
lisa fouladi: Well, I'd like to suggest is doing a stool test, and I would say amino acids would be good to give her amino acids. We only have 5 min left, so

562
01:24:18.510 --> 01:24:21.140
Deborah N: Alright, that was just. I just wanted to share that with you. Okay.

563
01:24:21.140 --> 01:24:48.000
lisa fouladi: Yeah, I mean, but it's very interesting. And you could prepare more stuff. We can do it properly on a on another call. So in terms of the electrolytes. She's running acidic. So Co 2 is bicarbonate. So you need to work on her acid alkaline balance, and Anion gap is high. So she is really running acidic. So it would be very important to help alkalize her somehow. Uric acid is optimal.

564
01:24:48.468 --> 01:25:05.330
lisa fouladi: Keep going. Amylase lipase are great omega threes so, and supplementation there would be a good idea. And then the lva, so she probably has some kind of hypoglycemia. Right, so the is she underway

565
01:25:06.680 --> 01:25:08.589
Deborah N: She has been losing weight

566
01:25:09.020 --> 01:25:09.420
lisa fouladi: Yes.

567
01:25:09.420 --> 01:25:19.460
Deborah N: So it's she wears baggy clothes, and she doesn't have a scale. So she, when I ask her about her weight, she doesn't look emaciated in her face. I will say that

568
01:25:20.540 --> 01:25:21.269
lisa fouladi: Oh, but I don't

569
01:25:21.270 --> 01:25:27.340
Deborah N: I worry about her muscle because she doesn't. She's not able to get up and really move around, you know a lot

570
01:25:27.550 --> 01:25:28.240
Deborah N: so so

571
01:25:28.390 --> 01:25:48.990
lisa fouladi: So there are. There are bed exercises she can do you know, with bands and things like that. To help preserve muscle and with the Ldh being low like that, it's really indicative of hypoglycemia so, and given that the HP one A/C was 4.8. It's pretty low, right?

572
01:25:48.990 --> 01:26:11.090
lisa fouladi: So just make sure that she has balanced meals, and Ggt is low, and that she really needs glutathione. Ggt is, and the biochemical pathway is related to Glutathione. So when it's Ggt is low or high, it tells us about the need for glutathione, and also B 6

573
01:26:11.734 --> 01:26:23.889
lisa fouladi: and then so serum iron is functionally low. But this Ferritin is okay. And so there may be an iron conversion issue there. So again, it's b 6,

574
01:26:24.350 --> 01:26:52.929
lisa fouladi: right? So you can keep going down. Cholesterol is okay. So the triglycerides are. So I don't know what she's eating. But you could look at her Carb carb content of her of her diet. Lipoprotein little. A so I know it has a little upward arrow under 75 is, I know this software wanted to be below 17. But thyroid looks to be okay.

575
01:26:52.930 --> 01:26:55.859
Deborah N: You say about little a what what should it be

576
01:26:56.520 --> 01:27:06.000
lisa fouladi: I mean, this software wants it to be below 17. But usually, if it's below 75, I don't consider it to be high. So there's nothing really

577
01:27:06.290 --> 01:27:12.480
lisa fouladi: to be done or worried about there. I mean, I think you know, it's just the software's own ranges.

578
01:27:13.005 --> 01:27:27.990
lisa fouladi: I don't think there's any kind of evidence that says it has to be below 17. All right, you can keep scrolling down. Okay? So the fibrinogen activity being elevated. That's an indirect marker of inflammation. So the glutathione should help

579
01:27:28.506 --> 01:27:48.230
lisa fouladi: and then the vitamin d. Oh, this is the person that is very deficient in vitamin d, so I'm wondering if she is malnourished if she has any kind of eating disorder or disordered eating because of, you know, it's a spectrum right disordered eating to eating disorder, you know, so

580
01:27:48.230 --> 01:27:55.489
Deborah N: Yeah, well, she hardly eats, because it always creates pain, and there are very few safe foods that she's found. And so

581
01:27:58.250 --> 01:28:03.409
lisa fouladi: So then, yeah, I would do a stool test. Why is pregnenolone so high

582
01:28:05.040 --> 01:28:13.620
Deborah N: You know, I don't know because she's not taking any. She she doesn't take any

583
01:28:14.676 --> 01:28:16.570
Deborah N: any medications.

584
01:28:16.670 --> 01:28:24.340
Deborah N: No, she does take something called the only thing that she's taking from the doctor is called Zen Pep, and it's a digestive enzyme

585
01:28:25.500 --> 01:28:40.380
lisa fouladi: Okay, well, we've got to figure out. You know. Do some further testing to figure out why pregnenolone is so high. And look at Pth intact, and I don't know why pregnenolone would be so high.

586
01:28:41.110 --> 01:29:02.260
lisa fouladi: The red blood cell indices are well, you know the I mean, there is a need for the B vitamins, and possibly well, we saw the serum iron was functionally low and Mchc is functioning low. So this is probably a b 6 issue, but I would do a full iron panel if she has an infection right? So the white blood cells are high.

587
01:29:02.260 --> 01:29:21.289
lisa fouladi: and so there is some kind of infection there, 10 would be just above the lab range. So you've got to look for some kind of infection. The neutrophils are elevated, so you've got to look for viruses. Was she ill when this blood test was taken?

588
01:29:22.240 --> 01:29:22.890
lisa fouladi: I do

589
01:29:22.890 --> 01:29:25.860
Deborah N: Not know. I'll I'll ask, but I don't know

590
01:29:25.860 --> 01:29:26.750
lisa fouladi: Okay, sweet.

591
01:29:26.970 --> 01:29:51.090
lisa fouladi: So neutrophils are elevated, absolute neutrophils are high. So this really speaks to some kind of bacterial, although it could also be viral monocytes are elevated, Eosinophils are so she's presenting like with an allergy profile as well. So you need to follow up with that and check her Ige levels in the serum.

592
01:29:51.657 --> 01:30:11.969
lisa fouladi: Ige Igm iga. But really, Ige, and you could follow up as well with a food sensitivity test. The diagnostic solutions. Test is a combo ige ige test, and that will give you an idea for food allergies.

593
01:30:12.080 --> 01:30:40.030
lisa fouladi: They would be Ige mediated, and then the Igg ones would be a good idea, but it looks like she hasn't. You know, mass. She's producing mast cells, so you know, that would fit in with the whole picture. She's not able to eat many foods, but really healing. The gut is going to be important, identifying the foods, the trigger foods and then calming everything down would be very, very important.

594
01:30:42.160 --> 01:30:55.422
lisa fouladi: and and then, of course, you know, addressing any kind of there would be kind of neuro inflammation associated with with pandas right? Just but

595
01:30:57.860 --> 01:31:00.980
lisa fouladi: did. Did she have any kind of Ocd

596
01:31:06.690 --> 01:31:15.310
Deborah N: not not not severe. Ocd, not. I wouldn't say so. She has every just about everything else but that

597
01:31:15.310 --> 01:31:28.549
lisa fouladi: Oh, poor thing, scroll down, you can. You can present this person again and later, hey, okay, so that's all there is. Alright. So yeah, I mean, the big take home for me is she has some kind of infection

598
01:31:28.650 --> 01:31:37.040
lisa fouladi: overt infection there. Whether it's bacterial or viral, I can't really say it's probably bacterial, but you need to find out what it is.

599
01:31:37.423 --> 01:31:56.699
lisa fouladi: So at this, at the moment this test was taken, she had some kind of infection, although her inflammatory markers were not high and except for fibrinogen and and really got to work on on gut stuff, finding foods that she can eat, and then supporting, I mean, things like.

600
01:31:56.700 --> 01:32:16.719
lisa fouladi: you know, amino acids would be good, having soups and pureed food and things like that. I mean if you could find out what the safe foods are, and then trying to come up with a balanced meal there and then getting the supplements in where she can't eat. If she doesn't eat fish or anything like that, to make sure she gets omega threes. Can she stomach supplements

601
01:32:17.130 --> 01:32:18.150
lisa fouladi: so it would be

602
01:32:18.150 --> 01:32:26.670
Deborah N: So she can only take maybe 3 a day, because if she takes them, then it interferes with her ability to even eat anything, because the pain

603
01:32:26.670 --> 01:32:29.919
Deborah N: absolutely she has this pain, even if she drinks water

604
01:32:30.570 --> 01:32:43.820
lisa fouladi: Closing patches. Vitamin patches, you know. Look for patches if you can take and and find out what what kind of you know, if the doctors can't find anything physiological, then we have to look at the functional tests.

605
01:32:44.285 --> 01:33:06.750
lisa fouladi: So I would do a stool test the Gi effects with the H. Pylori. Add on the Gi. Effects over the Gi. Map in this situation, because it gives us more information about the digestion and absorption, although the Gi. Map could tell us about H. Pylori, you know, so I don't know it's up to you, but I would also be tempted to do the H. Pylori.

606
01:33:06.750 --> 01:33:15.369
lisa fouladi: You can just get the H. Pylori and the virulence factors from diagnostic solutions. They're the only lab that quantifies H. Pylori.

607
01:33:16.080 --> 01:33:18.959
lisa fouladi: So it may be something there in the stomach

608
01:33:20.490 --> 01:33:21.240
Deborah N: Okay.

609
01:33:23.508 --> 01:33:26.979
lisa fouladi: I hope that was helpful. I know a rush. Sorry. Go on. Ask. Yeah.

610
01:33:26.980 --> 01:33:32.130
Deborah N: No, it's it was completely helpful. Thank you so much. With regard to the mast cells.

611
01:33:32.370 --> 01:33:38.709
Deborah N: Is there? Is there something some other comment you would you could make about mast cells, and how

612
01:33:38.710 --> 01:33:39.680
lisa fouladi: Because I do believe

613
01:33:39.680 --> 01:33:40.340
Deborah N: Yeah, that's okay.

614
01:33:40.960 --> 01:34:03.236
lisa fouladi: Yeah. Well, I mean the Monocytes and Eosinophils. They trigger the release of mast cells. So there's like a histamine kind of reaction going on here. It's a very complicated thing. If she's a mast cell type of person, and it would fit in with all of that. You've got to calm everything down. That's why I said, look at the Iges. Look at the Ige ige food sensitivities, and then you could also measure histamine

615
01:34:03.640 --> 01:34:23.070
lisa fouladi: and look at methylation. They're all related there. But you know, you've got to reduce the triggers right, whether it's environmental allergies or the foods. But the Eosinophils are not that high, but they are there. They're elevated, so are the Monocytes.

616
01:34:24.460 --> 01:34:28.009
lisa fouladi: So that is a they trigger the release of mast cells.

617
01:34:28.940 --> 01:34:38.329
lisa fouladi: I don't know if she's an allergic kind of person if she gets hives. If she has any kind of mast cell type symptoms, you know, hypersensitivity kind of person. So

618
01:34:39.080 --> 01:34:44.850
Deborah N: Yes, I mean, and and the hives and things like that, they kind of come and go. If

619
01:34:44.850 --> 01:35:06.749
Deborah N: have one other question, do we have time. For one thing, she has. She has something that I've I've identified. Well, she has. She showed me pictures of her hands. Okay? And starting with her wrists. They are brown. They're a brown color now. She never goes out in the sun. She's got very pale skin. Then she has brown here

620
01:35:06.930 --> 01:35:12.440
Deborah N: and brown. She's got brown at, basically at the knuckles and

621
01:35:12.770 --> 01:35:28.360
Deborah N: wrist. And so I looked it up and it and I can't remember. It's it's Hema Sitterin, I think it's called. It's where the I think this is what it is. Where the red blood cells

622
01:35:28.490 --> 01:35:31.680
Deborah N: sort of the integrity of the cell membrane

623
01:35:31.880 --> 01:35:38.729
Deborah N: allows the iron to be released, and then it deposits. So it's iron. And they said in and of itself

624
01:35:39.010 --> 01:35:42.720
Deborah N: that the discoloration is not harmful. But I think

625
01:35:42.720 --> 01:35:43.090
lisa fouladi: Think it's

626
01:35:43.090 --> 01:35:53.930
Deborah N: Sign of other things. And so it's her cell membrane. I think the integrity, I think, is compromised. So I was looking at essential fatty acids, and

627
01:35:54.070 --> 01:35:55.970
Deborah N: I was just trying to.

628
01:35:55.970 --> 01:35:56.920
Deborah N: Well done

629
01:35:57.200 --> 01:36:07.049
lisa fouladi: Well, the Omega, I mean it's we're over well over time now. But the Omegas she's low on her omega, so you can support the Omega. So if she can't take supplements and think about the patches

630
01:36:07.060 --> 01:36:27.960
lisa fouladi: and and then, you know, I think you know, she probably needs medical management. It's really sounds like she needs medical management, so she needs to be with a doctor who can help calm down her immune system with with medicine until everything is calmed down. And she needs to be with a mass mast cell specialist.

631
01:36:27.970 --> 01:36:33.673
lisa fouladi: And then and then you could look functionally at other things.

632
01:36:34.710 --> 01:36:40.759
lisa fouladi: she's she's just moved, and she is looking for a a new doctor and got a recommendation from her old doctor. So

633
01:36:41.200 --> 01:36:41.600
lisa fouladi: thank you.

634
01:36:42.500 --> 01:36:43.060
Deborah N: So.

635
01:36:43.060 --> 01:36:52.820
lisa fouladi: Okay, well, I'm happy to discuss this again on another call. Sounds like she has a lot of stuff going on with her. I feel very bad for her, poor, poor person, only 20 years old.

636
01:36:53.090 --> 01:37:11.299
lisa fouladi: So you know, I'm glad that you're there to help her and ferret out the functional imbalances. But yeah, she does need medical management. So thank you. Everybody for a great call. I'm glad that everybody spontaneously brought the lab results. So we can have a productive call, and those are the best.

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lisa fouladi: and and submit your cases and if you don't have a case to submit, then do like we did today. Just show up and we'll go through them. Okay, everybody

638
01:37:24.780 --> 01:37:25.610
Deborah N: Thank you. Lisa

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lisa fouladi: Thank you. Take care and see you next month, or on another call. Okay? Alright, bye, bye.