The narrowing of the pulmonary valve (white arrow in diagram) may cause the right ventricle (RV) to pump harder to move its supply of blood into the pulmonary artery (PA). The pulmonary stenosis may interfere with the proper functioning of the right ventricle and, in extreme cases, lead to right ventricular failure.
This increases the blood pressure in the right ventricle and may result in the thickening (hypertrophy) of its walls.

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