Lustig explains that high levels of insulin, caused by eating too much sugar, causes the body to store more calories as body fat, which starves muscles cells, and makes you feel tired and hungry, and therefore you eat more to compensate for this, leading to weight gain. So, as Lustig explains, when we eat the modern American diet and consume lots of sugar-laden foods, the higher your insulin levels go which blocks leptin in the brain, the more food your store, the hungrier you get, and the fatter you become.

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