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The human species of the paleolithic era did not suffer the medical problems seen by modern societies. As stated on the 'Nutrition' page, multiple medical problems can find their roots in nutrition.
There are numerous substances that irritate our gut lining and increase systemic inflammation. My recommendation is that patients adopt a full (no grain, no dairy, no legumes) paleo diet for 30 days. You may not have intolerance to grains, gluten, legumes, or dairy and can eat them without apparent issues. I believe the best way to start is a basic Paleo Diet for 30 days and re-evaluate how you look, feel, and perform.
I don't believe there is a 'one-size-fits-all' solution but I do believe that the 'Paleo Diet' is the best starting point for the most number of people. Let me start by saying that the scientific evidence supporting this diet for health and weightloss is substantial. Starchy vegetables (potatoes, yams, sweet potatoesВ - yes, that means no french fries) - there is actually a time that these are acceptable but it is in a narrow window just following exercise. I have talked with patients who have said "well, I cut out bread and it didn't make a difference." The problem was that they were eating other substances that had the same ingredients so cutting out bread was a superficial correction that didn't eliminate the source of the problem. The foods on the paleo diet are more nutrient dense and less calorie dense than the foods that are 'banned' and this often prevents excessive caloric intake. However, I would argue that you CAN eat too much of a good food and we should, therefore, moderate our intake and be smart with our food choices. If you want toВ MAXIMIZE your health and body habitus, you should strongly consider the Paleo Diet!
Again, the best way to improve your health is to do a full 30 days on the Paleo diet, no cheating. Wheat - in addition to the gluten problem, wheat has a higher glycemic index than table sugar (sucrose). The idea for the 'full paleo' is to give our bodies a chance to heal and purge the anti-nutrients in these foods. Once you have been on the 'full paleo' for at least 30 days then you can start adding some foods back in on a limited basis and evaluate how things are going with each food.
Work your way up the list in the opposite order that you removed them evaluating each of them in the same manner.
Also, bear in mind that some of the problems with some of these foods don't necessarily make you feel bad and the manifestations of their effects may not show upВ  for years!
The Paleo Solution - This book was written by Robb Wolf and is, quite simply, an excellent book. The Paleo Diet website - this is Dr Loren Cordain's website with links and information about the book. The Paleo Diet For Athletes - Dr Cordain made a couple of changes to the diet with an athlete in mind. Growing Up Paleo - a websited dedicated to a paleo lifestyle during pregnancy and childhood. What Your Hands Can Tell You About Your FoodIf you’ve read any of my stuff or hear me talk at all then you know I recommend eliminating (or dramatically reducing) gluten from your diet. If we look at the outside part of the seed, that’s the part that comes in contact with the environment and that’s the one that has the concentrated sources of anti-nutrients, so all these nasty things that we’re finding in grains that cause problems are concentrated in the outside portion of it.В  So that’s where the fiber is, is in the bran portion, and that’s where many of the anti-nutrients are.
Now, beta cells only regenerate at a rate of about 1 percent per year, so it’s not very fast.  Is it possible that sometimes there are beta cells that are almost dead, but they’re not all dead, and when the body stops attacking them, they start functioning again.

What we’re thinking in both anecdotal cases we’re aware of, is the people that came into function were younger people, they were two young women that had recently been diagnosed, and so our thinking is that they perhaps had 10 or 20 percent of their beta cell function remaining, and then with the cessation of the immune system assault, on the beta cells, that stem cells started to regrow, and the remaining cells in the stem cell regrowth perhaps were the explanation.  We didn’t know, because most researchers had never heard about this before.
Now one of the women that you had mentioned to me before who was a type 1 diabetic who stopped taking medications, on her website she says she is now taking medications. There is also a woman who is advertising on the web right now about her twin boys, who she put on a what I believe she describes as a plant-based diet, where they were both diagnosed as Type 1 diabetics, and now they don’t take any medications.
That doesn’t make a lot of sense to me because the only way you can eat a plant-based diet is by eating grains and legumes, and those are two factors that can irritate the gut.
Plus those have a fairly high carbohydrate content, sugar turning into content, which would be more likely to stress the pancreas and the insulin system.
Yes, a higher carbohydrate diet before insulin was synthesized and before people could inject themselves with insulin one of the few ways that people could counteract the disease, because it wasn’t until the early sixties that the distinction was made between Type 1 and Type II diabetes, was to reduce the carbohydrate in their diet,  prior to the day and age of the synthesis of insulin and injecting it. If the numbers are correct, with 1% or 2% of the U-S population testing positive for Celiac Disease now, there’s no way in God’s green earth that we should be recommending whole grains to the entire population.  It absolutely makes no sense.
I suspect you’ve seen some markers that would among other things, tell whether people are eating what they think they’re eating .
And I believe from the research that you’ve done, you’re aware of some other markers that would be worth going after in a blood test.  If there was a comprehensive panel that had those kind of things on it, it could answer a lot of questions for people with chronic conditions. And also you would suggest that even though there are no saponins and no lectins in sugar, that can can lead to leaky gut, too.  In a very different pathway, but that can do it too. High glycemic load carbohydrates we know cause increased intestinal permeability, and one of the mechanisms may be the change in gut flora we’re seeing when people eat those kinds of foods, when people eat a lot of sugar and refined carbohydrates.  It could potenially alter the gut flora in a manner that can increase intestinal permeability.
I do indeed, and it’s published by John Wiley and Sons and the title of the New Book is The Paleo Answer, and I’ve written about everything that I haven’t written about in my other two books, and it’s got all of the latest information right up to 2011.В  So we’ve got the best science in there showing you that saturated fats are okay to eat, and why vegetarian and vegan diets are not a good idea, and why taking antioxidant vitamins might shorten your life. I think the paper you’re referring is about how Maternal Immune Activation in mice, and how it relates to autism in their offspring, and it just came out in CELL, and it DOES talk about leaky gut, and it does indeed describe how giving a probiotic microbe to the young mice exhibiting autistic spectrum behaviors exhibited less of those behaviors after the probiotic. I disagree with the underlying assumption that anti-nutrients were not part of the paleo-lithic diet. Loren Cordain has some research papers on his website, that give helpful background on these issues. Actually, Loren Cordain is pretty trim, though he sometimes slouches in his chair when he’s being interviewed, no matter how much I ask him not to!
Thanks Robb,There is some evidence that alpha amylase inhibitors in legumes and whole grains can enlarge the pancreas in animal models.
1) Get most of your calories from the meat of organic grass-fed animals or organically grown animals eating the foods that they are supposed to eat. I had some quinoa flakes breakfast cereal for dinner the other night and later that evening I felt like my insides were being ripped out.
Breakthrough nutrition program based on eating the foods we were genetically designed to eat meats, fish, fresh fruits, veggies, nuts and seeds and other foods that made up the food groups of our Paleolithic (Stone Age) ancestors. The Paleo Diet revised edition features new weight-loss material and recipes plus the latest information drawn from breaking Paleolithic research. Six weeks of Paleo meal plans to jumpstart a healthy and enjoyable new way of eating as well as dozens of recipes.
This bestselling guide written by the world’s leading expert on Paleolithic eating has been adopted as a bible of the CrossFit movement. The Paleo Diet is the only diet proven by natural selection to fight disease, provide maximum energy, and keep you naturally thin, strong, and active-while enjoying every satisfying and delicious bite. The material on this web site is provided for educational purposes only and is not to be used for medical advice, diagnosis or treatment. Hunter-gatherer societies still in existence also lack the medical problems which are common in other 'neolithic' societies.

I see patients daily that have vague medical symptoms ranging from headaches to skin problems, from allergies to stomach pains - almost all of these patients improve on a proper diet targeted to improve their symptoms. There may be other dietary changes that need to be made but this is the launching pad for most medical problems. That may sound like a dramatic departure from mainstream dietary recommendations and I would agree.
However, I have yet to come across one person who has adhered to the diet walk away saying that it wasn't beneficial. We will include the starchy vegetables (potatoes, sweet potatoes, and yams) in this category. Milk does have some very good properties (especially for muscle building, it is very anabolic) but not everyone tolerates it in the same way. If you are a serious, hard-core athlete then you should consider reading this book as well. I have a lot of patients who ask me if I’ll test them for Celiac disease or gluten intolerance. Hundreds of scientific papers show that legumes and grains increase intestinal permeability, and they do it through the mechanisms we talked about earlier, through lectins and saponins, and what are called thaumatin-like proteins, so I would say that vegetarian or vegan diets would be one of the worst ways a person with autoimmune disease could go.В  I recommend not doing that. Cordain looks good enough to eat (spitted slowly over an outdoor hearth) nah just kidding the guy looks great to me! I have eliminated all wheat and dairy from my diet but I still consume a decent amount of quinoa, brown rice, oatmeal and beans. Loren Cordain demonstrates how, by eating your fill of satisfying and delicious meats and fish, fresh fruits, snacks, and non-starchy vegetables, you can lose weight and prevent and treat heart disease, cancer, osteoporosis, metabolic syndrome, and many other illnesses.
We have repetitively seen an improvement in overall health when adopting similar nutritional diets.
This diet is based on eliminating the most common toxins and substances that cause a whole host of problems with our immune system, gut, energy, thyroid, adrenals, and a whole host of other issues. They often use different flours that have a higher glycemic index but do it to avoid the gluten.
However, it is still fairly common that, when I mention and describe the Paleo Diet, patients change their expression. The Functional Medicine approach to nutrition means that each person has an adequate & functional nutritional status. This is to get all the essential nutrients (except vitamin C) without consuming excessive carbohydrates. The only way to know is to cut these foods out completely and then re-address each of them. This is a great summation, and I highly recommend his new book for a new plateau of health (if you aren’t already there it is a great ride)!
The problem is that you can remove one of them and the gut doesn't heal due to the presence of the others. The only way to address this is to remove all of the most likely substances completely for a short period of time, let the gut heal, and then gradually re-introduce each substance and evaluate the response. You may even be able to bypass some of the fatigue, decrease in energy, and cravings associated with the transition.
I need to see evidence of actual clinical disease caused by eating grains (specifically brown rice, oatmeal, & quinoa) and legumes, and such disease is cured by their omission.

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