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Polyunsaturated phosphatidylcholine liver,pure aloe vera plant for acne,quick paleo meals,healthy dishes indian - Within Minutes

PhosChol (PPC) interferes at various sites in the pathological processes of dyslipoproteinemia and atherosclerosis by means of its polyunsaturated phosphatidylcholine (PPC) content.
Due to the greater capacity of PPC-enriched HDL (high-density lipoproteins) to take up cholesterol (1), a greater portion of atherogenic cholesterol is converted into a form that can be more readily transported by HDL and which is rapidly metabolized in the liver. The cholesterol linoleate is transported to the liver by HDL and there metabolized and excreted as bile acids with the bile.
Phosphatidylcholine is an intriguing nutrient with a little-known but impressive range of functions in human health.
The human body can synthesize choline by converting the phospholipid phosphatidylethanolamine to phosphatidylcholine.(1) Phosphatidylcholine can then be broken down to provide choline.
Stay tuned for subsequent sections of this article discussing the applications of phosphatidylcholine in liver health, intestinal health, and brain function.
In Part I, we saw that choline is an essential nutrient with a role in liver metabolism of cholesterol. Betaine is a special derivative of choline that acts as a methyl donor in the metabolism of homocysteine, and may also have a therapeutic role in fatty liver. In Part III, we will discuss the evidence for phosphatidylcholine’s role in the maintenance of healthy intestinal function.
As reviewed in Part I, phosphatidylcholine serves an important function as a component of the cell membrane, maintaining membrane integrity and functioning in cell-to-cell communication. One study in 60 patients with ulcerative colitis not responding to steroid therapy found that supplementation with 500mg phosphatidylcholine four times daily (total 2g per day) for 12 weeks was able to decrease disease activity by 50% or more in 50% of the patients receiving the treatment.(1) This was compared to such improvement in only 10% in the placebo group. A second study examined 60 patients with non-steroid dependent ulcerative colitis.(2) Supplementation with phosphatidylcholine resulted in significant improvements in disease remission rates, endoscopic findings (scope & imaging of the inside of the intestine), and quality of life scores, compared to placebo.


Finally, a third study was conducted in 40 non-steroid dependent patients with chronically active ulcerative colitis.(3) This study found that supplementation with 1g or 3g or 4g per day phosphatidylcholine resulted in significant improvements in disease activity after 12 weeks. In addition to ulcerative colitis, protective effects have been shown for phosphatidylcholine on the stomach. Supplementation with a slightly different form of choline, CDP-choline, also known as citicoline, has been shown to preferentially increase synthesis of phosphatidylcholine in the brains of older adults.(2,3) As a result this form, citicoline, has been further researched for its effects on memory and cognitive impairment.
The liver is a large glandular organ, whose functions include decomposition of red blood cells, plasma protein synthesis, hormone production, secretion of bile, and conversion of sugars into glycogen, which it stores. PPC also has strong antioxidant properties, which means it may reduce oxidative stress (cellular changes that generate free radicals), may help protect the liver by modulating its immune response. PPC is also incorporated into blood lipoproteins, helping to extend its benefits beyond the liver to promote arterial health.
This is how PPC supports the transport of cholesterol from the periphery to the liver, Fig. Humans consuming a choline-deficient diet have been shown to develop fatty liver and liver damage.(1) On the other hand, supplementation with choline has been shown to reduce liver damage due to fatty liver and reduce fat accumulation within cells.
When fat and cholesterol are consumed, they are absorbed from the intestine and sent to the liver for “packaging” on transporter proteins in order to be sent out to the rest of the body. The liver is also responsible for processing many vitamins and nutrients into a form that can be utilized by the body, as well as detoxification of various substances. Choline functions as part of the very low density lipoprotein (VLDL) that transports cholesterol from the liver to the rest of the body.(2) Therefore, when the body is deficient in choline, fat and cholesterol accumulate in the liver, resulting in fatty liver and damage.
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression.


Plasma lipid parameters in patients with alcoholic fatty liver after treatment with essential phospholipids.
Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Choline supplemented as phosphatidylcholine decreases fasting and postmethionine-loading plasma homocysteine concentrations in healthy men. A pilot study of polyunsaturated phosphatidyl choline in fulminant and subacute hepatic failure. A number of studies have examined use of phosphatidylcholine as a treatment for ulcerative colitis(1-3) and in stomach ulcers.(4,5) In both these conditions, the integrity of the cells lining the digestive tract is seriously damaged, resulting in severe pain, and in ulcerative colitis, cramping, diarrhea, and bleeding.
Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study.
Modern living involves daily exposure to substances that are toxic to our bodies, which imposes a heavy load on the liver. Certain lifestyle risks and medical conditions make it all the more important to ensure that the liver is being maintained at its functional best.
This process is a well-documented function of high-density lipoprotein (HDL) that involves the transport of cholesterol from the arterial walls to the liver for processing.



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