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Seable gives you the chance to conduct a tailor made holiday that improves confidence and skills for life, challenging perceptions of disability and blindness. The gut becomes leaky in the sense that bacteria, fungi, parasites, undigested protein, fat and toxic waste normally not absorbed into the bloodstream in the healthy state, pass through a damaged, hyperpermeable gut membrane. Inflammation causes the spaces between the cells of the gut wall to become larger than usual. If the antibodies end up attacking the lining of the gut itself, the result may be colitis or Crohn's disease. This ongoing inflammation also damages the protective coating of antibodies normally present in a healthy gut called IgA. Not only can leaky gut create food allergies as the proteins we consume are activating antibodies, but the microbes in the gut can cross over into the blood stream creating a toxic burden that overwhelms the liver's ability to detoxify.
Finally, leaky gut may contribute to a long list of mineral deficiencies because of the ongoing inflammation and damage to carrier proteins.


The abnormally large spaces present between the cells of the gut wall allow the entry of toxic material into the bloodstream that would normally be eliminated. This can be verified by special gut permeability urine tests or microscopic examination of the lining of the intestinal wall.
The antibodies created by the leaky gut phenomenon against these antigens can get into various tissues and trigger an inflammatory reaction in that tissue when the corresponding food is consumed or the microbe is encountered. Often in severe cases of leaky gut, patients will develop sensitivities to perfume, cigarette smoke or other environmental chemicals. The most common are iron deficiency, vitamin B12 deficiency, magnesium deficiency which can lead to fatigue, neuropathies or muscle pain.
The immune system starts making antibodies against these larger molecules because it recognizes them as foreign, invading substances. It is easy to see that practically any organ or body tissue can become affected by food allergies created by the leaky gut.


In the clinic we often find patients with leaky gut or autoimmune disease also have microbial infections ongoing in the gut. Copper deficiency can occur in an identical way leading to high blood cholesterol levels and osteoarthritis. The immune system becomes hyperstimulated and over-reactive to substances that are not necessarily supposed to be dangerous.
Fortunately doctors are beginning to realize the essential role that the gut plays in these disease.
Understanding the leaky gut phenomenon helps us see why allergies and autoimmune diseases develop and how to design therapies to restore intestinal integrity and reverse leaky gut.



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