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Intestinal permeability test kit uk,lose weight by eating more,healthy food menu card - For Outdoors

Assessment of intestinal permeability is a very sensitive, non-invasive technique to detect and manage small intestinal disease in dogs. The normal small intestine is lined by finger-like villi covered by absorptive epithelial cells which form an effective barrier between the lumen and the lamina propria. Permeability testing can be more helpful than intestinal biopsy alone in the detection and management of intestinal disease.
Application of permeability testing to identify dietary sensitivity as the cause of intestinal damage is illustrated in the figure below.


Intestinal permeability has been shown to be increased in approximately 50% of clinical cases with SIBO, even when there are no histological abnormalities.
This figure shows that dogs with high permeability after 4 weeks antibiotic therapy are 3 times more likely to relapse despite an apparent clinical response to treatment, and continuation of antibiotic therapy is therefore recommended. This shows test results in a 3 year-old Golden retriever with chronic vomiting and diarrhoea.
Normalization of intestinal permeability following 4 weeks of antibiotic therapy indicates successful repair of mucosal damage.


Differences are more marked after 3 months of treatment as dogs with high permeability are approximately 8 times more likely to relapse. High permeability pre-treatment indicated intestinal damage which resolved on a chicken and rice exclusion diet with relapse on dietary challenge, indicating true dietary sensitivity.



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