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Physical activity, sleep, sun exposure and dietary needs of every living organism (including humans) are genetically determined. As such, we recognize the profound changes in diet and lifestyle that occurred after the Neolithic Revolution – and more so after the Industrial Revolution and the Modern Age – are too recent on an evolutionary time scale for the human genome to have fully adapted. Put Paleo into action with The Paleo Diet Cookbook and eat your way to weight loss, increased energy, and lifelong health-while enjoying delicious meals.
In terms of our actual genetic material, genetic adaptations to diet, such as lactase persistence, are selected for over many generations on a population-wide basis. It’s also important to note that the introduction of meat into the human diet plays a very important role in our evolutionary history, as the consumption of nutrient rich and calorie-dense animal food is what made it possible for our species to develop such big brains. The beautiful Maasai people thrive on a high-fat diet that primarily consists of meat, milk, and blood.
In terms of diet composition, estimates show that “whenever and wherever it was ecologically possible, hunter-gatherers consumed high amounts (45–65% of energy) of animal food.
Okay, but what if we turn our focus away from paleolithic tribes and contemporary non-westernized societies eating ancestral diets and shift our attention towards the changes that have occurred since the agricultural revolution (10000 years before present). While everyone agrees that most of the modern processed food shouldn’t be a major part of a healthy diet, there is more controversy regarding foods that came with the neolithic era.
In general, if we look at human nutrition through the lens of evolution it becomes clear that focusing on macronutrient and micronutrient intake is a simplistic view on diet.
Meat, seafood, eggs, vegetables, fruits, berries, nuts, dairy (preferably raw, fermented, and full-fat), and legumes should make up the basis of your diet.
In this regard, despite the occurrence of important genetic changes since the Agricultural Revolution, most of the human genome is comprised of genes selected during the Paleolithic Era, a period that lasted from about 2.5 million to 11,000 years ago.


Loren Cordain’s The Real Paleo Diet Cookbook with 250 Paleo recipes prove following The Paleo Diet is as delicious and inspiring as it is healthy.
In other words, our human genome adapts slowly to major dietary shifts, such as the ones that came with the neolithic revolution. Diet has a significant impact on these epigenetic switches, and this epigenome could therefore be thought of as the bridge between the food we eat and our DNA.
Some of our ancient ancestors travelled into areas with little access to edible plants and therefore ended up with a diet based primarily on animal source food, while others settled down in regions of the world where fruits and vegetables are plentiful. If we look beyond the introduction of meat in the human diet, the two major dietary shifts came with the agricultural revolution, characterized by the introduction of grains, dairy, and legumes (were probably also consumed in the paleolithic in smaller amounts) in the human diet, and the industrial revolution, characterized by the introduction of refined vegetable oils, refined grain products, and sugar-laden junk food.
While this historical perspective on diet doesn’t really provide any firm conclusions as to how we should eat, it does provide a general framework we can combine with modern science in order to understand human nutrition. To find a good fundamental definition of a healthy diet we should look at the very thing that makes us who we are, DNA.
Although humans are able to adapt to a wide range of dietary patterns, that clearly doesn’t mean that all diets are the same.
His research emphasis over the past 20 years has focused upon the evolutionary and anthropological basis for diet, health and well being in modern humans. If we change our diet, the epigenome will adapt by upregulating certain genes and downregulating others (2,3,4).
However, if there’s one thing we know about hunter-gatherer diets, it is that they all contain some type of animal source food (10). This is the way humans have evolved for most of our evolutionary history; dietary patterns varied depending on climate, topography, and other environmental conditions.


This might sound like a naturalistic or alternative approach to diet, but if we really think about, nutrition is so much more than just providing energy to our cells.
Since DNA is the molecule that encodes the genetic instructions used in the development and functioning of our body, focusing on the interaction between our genomes and our environment is the natural approach when trying to define what a healthy diet really is. Even the most hard training endurance athlete need much more than 40% carbohydrate in their diet.
The mismatch between our ancient genome and the modern environment has major implications for human health, and the purpose of this site is to investigate how we can reconnect with nature, rewild our bodies, and reclaim our health, while still enjoying the benefits of modern technology.
Cordain’s scientific publications have examined the nutritional characteristics of worldwide hunter-gatherer diets as well as the nutrient composition of wild plant and animal foods consumed by foraging humans. This means understanding the role of nutrition as a selective pressure and focusing more on diet quality, food production and processing, and nutrition and gene expression. He is the world’s leading expert on Paleolithic diets and has lectured extensively on the Paleolithic nutrition worldwide. Cordain is the author of six popular bestselling books including The Real Paleo Diet Cookbook, The Paleo Diet, The Paleo Answer, and The Paleo Diet Cookbook, summarizing his research findings.



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Comments to “Genome diet”

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  3. I_S_I:
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