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There are dozens of different sugars in the world, but for the purpose of this article what we need to understand are sucrose, glucose, and fructose.
Glucose, besides being present in sugar, honey, and other sweeteners, is derived from starch — when we eat starches, our bodies convert them into glucose which we use for energy. Fructose is a naturally occurring sugar present in fruit, honey, and cane sugar, among other things. Before cane sugar, and more recently high-fructose corn syrup, humans didn’t have a whole lot of access to either of these sugars. Now a’days, we get most of our sugars from cane sugar, corn syrup, and high-fructose corn syrup.
In part one of this series, Cane Sugar and How It’s Made, I mentioned how much sugar consumption has increased in our diets over the past hundred years.
The invention of HFCS was a huge boon to the food industry, because it was much cheaper to produce than sugar.
A good example of this is when soft drink manufacturers switched from using cane sugar to corn sugar.
Some studies also suggest that an increase of fructose in the diet can mess with the body’s production of the hunger-regulating hormone leptin. While it is proven that fructose triggers the production of uric acid (no matter where that fructose comes from), it is not clear what makes high-fructose corn syrup so much worse than sugar. One notable difference between regular sugar and high-fructose corn syrup, which may account for some of this disparity, is that the monosaccharides (single sugar molecules, in this case fructose and glucose) found in sugar are bound to one another to create sucrose, which the body has to break apart before digesting, while the monosaccharides in HFCS are not bound together, allowing them to be absorbed more quickly and directly. Honey also comes into question, weighing in at about 38%В fructose (the rest being made up of glucose, maltose, and other sugars).
One of the hardest parts about researching subjects like this is that for every study claiming fructose is bad, there is a counter-study saying that the first study is false, or doesn’t have enough evidence.
And some people are looking for the good side of fructose.В One study suggests that certain amounts of fructose can be a good thing in athletes and people who exercise, because fructose can help with fluid absorption and performance. Sucrose (aka, table sugar) is a disaccharideВ — this means it is made up of two sugar molecules joined together. The body metabolizes glucose in the intestinal tract, where it gets absorbed into the blood stream causing a rise in blood sugar levels. The fructose available to us was found in things like fresh fruit and berries, dates and figs, honey, etc.

In cane sugar, glucose and fructose are paired with one another — it is 50% glucose and 50% fructose.
In the 1800’s, humans consumed approximately six pounds of sugar per person per year, compared to an estimated 130 pounds per person per year today. It was also much sweeter than regular sugar, meaning that manufacturers could use less of it to get the same results. This, along with findings which show sugar to be a highly addictive substance, may account for why so many people have trouble controlling how much they eat. The results showed the group of rats drinking high-fructose corn syrup gained a significant amount of weight as compared to their sugar-drinking counterparts.
Some people are more tolerant than others, and those who already have diabetes or insulin resistance may indeed have to watch the amount of sugars they take in, even from fruit. Some manufacturers are switching their products from HFCS to cane sugar with the expectation that consumers will purchase more of them if they believe them to be healthier than they really are. You will find interesting info too about fructose metabolism and storage – different than glucose in very important ways, and about the combined effect of taking in too much fructose and fat together, and effects of all of these in relation to insulin, fat production (lipogenesis) by the liver, and fat storage.
I came across a few articles discussing the effects of fructose in combination with fats and other foods, but it was clear a lot more research needs to be done. To get the sugars where they need to go, the pancreas releases insulin, which binds to the glucose molecules and carries them off to the cells that need the energy most (and, if there is excess glucose, carries it off to be stored as fat). It is often thought of as a healthier type of sugar because it has a low glycemic index, meaning it has a very small impact on blood glucose and insulin levels.
The amounts found in most fruits and vegetables pose very little concern when compared the amounts found in processed sugars. No, the biggest difference is that a piece of fruit contains vitamins, minerals, antioxidants, and other nutrients our bodies need to function properly and process the sugars it takes in. For the rest of us, however, if we were to eat a diet of only natural sugars (no added sugars), it would be very difficult to overdose. That is because it is the primary source we have of really concentrated fructose (besides Agave, which, while organically occurring, has even more fructose than most HFCS). Foods with a high GI are those which are rapidly digested and absorbed and result in marked fluctuations in blood sugar levels.
This is because fructose doesn’t get absorbed in the intestinal tract the way glucose does.

According to the US Department of Agriculture, consumption of HFCS increased more than 1000% between 1970-1990, and now constitutes more than 40% of all added sugars.
The fructose and glucose present in HFCS are absorbed by the body the same as any other source of sugar.4. This is based on the claim that HFCS contains 55% fructose, as compared to the 50% present in sucrose. High-fructose corn syrup (or HFCS) has В been treated with more enzymes, which convert some of the glucose into fructose. While the purified fructose caused an elevation of triglycerides and inflammation, the honey made virtually no change. Recent studiesВ which look at the concentration of fructose in popular soft drinks show that most HFCS can range from 55%-65%, which is substantially higher than is stated according to their labels. And I agree 100%, I would take fructose over sucralose (or most other artificial sweeteners) any day!That thing about the water is just insane! So for some people, they think that they might as well skip the orange and reach for the treat that they really want, but before you reach for the Oreos, we want to teach you the difference between sucrose (table sugar) and fructose (the sugar in fruits & other organic foods).
The breaking down of fructose in the liver triggers the production of uric acid, among other things, which may be harmful in large amounts. HFCS is commonly believed to contain 55% fructose, but studies now show it can range anywhere from 55% fructose to 65% fructose, if not more. Even more important is the discovery that some products contain something called HFCS-90, which, as the name suggests, is about 90% fructose. Because it takes time to break fruit down, your body does not release insulin when you are eating fructose.
Sucrose is made up of one part fructoseВ and one part glucose, glucose stimulates the rapid release of insulin to manage your blood sugar levels. The body does absorb glucose and fructose in a similar manner no matter where those sugars come from, however the problem presented with HFCS is that the concentration of fructose is at a level that may be harmful, especially when consumed in the amounts found in the average American diet.4. Pasta, potatoes and rice are great with anything as long as you are careful about the sugar content of the sauces.

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