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Folic acid deficiency anemia,indian vegetarian recipes in hindi,gluten free diet weight loss before and after - For Begninners

Folic acid is a water-soluble vitamin of the B Group and it is the only active form of folate absorbed by the body.It is synthetically produced,because it is not naturally found in food,contrary to folate. Folic acid structure is composed of the union of three molecules: 6-metilpterina acid, p-amino benzoic acid (PABA), and glutamic acid. Folate enter cells as monoglutamates, but are rapidly modified by addition of four to eight glutamate residues to form long side chains. The enzyme 5,10- metiltetridrofolato reductase ( 5,10- MTHFR ) is an enzyme dependent on folic acid that exists in polymorphic form ( genetic polymorphism ). From the earliest stages of pregnancy , the product of conception becomes a huge consumer of folate, because of the intense processes of cell proliferation and differentiation. The integration with folic acid does not reset the risk that the product of conception developments defects in neural tube closure , but it significantly reduces. Folic acid fortification is a process where folic acid is added to flour with the intention of promoting public health through increasing blood folate levels in the populace.Since the discovery of the link between insufficient folic acid and neural tube defects, governments and health organizations worldwide have made recommendations concerning folic acid supplementation for women intending to become pregnant. A person suffering from folic acid deficiency will have very low levels of folic acid, a form of vitamin B. Folic acid deficiency is a common and widespread vitamin deficiency that affects more men than women and occurs at the age of 30 years and older. When the body is unable to get sufficient amounts of folic acid, a condition known as folic acid deficiency anemia occurs. While folic acid is present in food, some people are unable to get enough folic acid-rich food in their diet. Folic acid deficiency occurs when a person is unable to get an adequate amount of food rich in folic acid.
When the body is unable to absorb folic acid from the food a person eats, a folic acid deficiency ensues. People who are at risk for developing folic acid deficiency are elderly individuals, people who are alcoholics, smokers, women who take birth control pills, people who are subject to a great deal of stress, and patients taking sulfa antibiotics or undergoing anticonvulsant therapy. Folic acid deficiency causes anemia and other symptoms, such as fatigue, paleness, palpitations, weakness, paranoia, light-headedness, memory loss, lack of appetite, loss of weight, an eating disorder known as anorexia nervosa, low attention span, a tendency to have bad moods, and a sore or inflamed tongue. Upon consultation, the doctor will take down the patient’s medical history and ascertain all the accompanying symptoms of folic acid deficiency anemia.
The goal in treating folic acid deficiency is to ensure that the patient gets enough of this B vitamin in their body in order to reduce symptoms and eliminate anemia.
Other alternative remedies for folic acid deficiency include reflexology, particularly in the regions of the body that influence the spleen or the liver.


Folic acid deficiency can be treated within three weeks if the patient is able to take in an adequate amount of folic acid, either from food or from supplements. To prevent folic acid deficiency from occurring, consuming raw or slightly cooked green leafy vegetables on a daily basis is sufficient to maintain normal levels of folic acid in the body.
A group of zinc-dependent intracellular enzymes, the conjugase , are used to obtain folic acid, which is the form normally absorbed from the gut, and then, folic acid is further reduced by the enzyme 5,10- metiltetridrofolato reductase (5,10- MTHFR) in the liver to 5MTHF (5-Methyl-Tedra hydro-folate) that is the active form of the vitamin itself, responsible for significant biological activities known and that is obteined after reduction in diidrofolic acid by diidrofolate reductase. The reasons may be related to infectious diseases, drug therapies, pregnancy or malabsorption, and the consequences are problems in the synthesis of DNA and RNA , but also defects in production of bone marrow cells.Folate is required to make red blood cells and white blood cells and folate deficiency may lead to anemia.
The increase in maternal erythropoiesis contributes to the needs of folic acid during pregnancy in view of childbirth blood volume will be increased by 30-50%. Women who could become pregnant are advised to eat foods fortified with folic acid or take supplements in addition to eating folate-rich foods to reduce the risk of serious birth defects. This causes a condition known as anemia that is brought about by very few red blood cells that grow to a huge size. Folic acid is an important component of the body’s RNA and DNA, and it is needed for red blood cell formation.
The B-vitamin folic acid plays a part in the manufacture of new cells, including red blood cells.
Dietary sources of folate include green leafy vegetables, citrus fruits, oatmeal, red beans, wheat germ, liver, mushrooms, peanut butter, and soy. The inability to absorb folic acid may be due to several factors, which include alcohol abuse and kidney ailments that require dialysis or regular blood cleansing processes. Some people who exhibit symptoms of folic acid deficiency have low levels of vitamin B12, which are responsible for symptoms similar to folic acid deficiency anemia.
In line with this, the doctor may prescribe folic acid supplements and advise the patient to avoid any of the prohibited substances that may exacerbate the loss of folic. Any complications that may arise, such as fever, chills, muscle aches and other non-related symptoms should necessitate a visit to the doctor, particularly if the symptoms of folic acid deficiency do not improve. If left untreated, folic acid deficiency anemia may be responsible for the occurrence of infertility and may render the sufferer increasingly susceptible to various infections. The food folates are absorbed mainly in the first intestinal tract, including the duodenum and the ileum, and in the proximal third of the small intestine, although they may be absorbed throughout its length. The foletes that are used ase coenzymes and regulatory molecules in the body are all in the reduced form as tetrahydrofolate derivetes. For this reason folic acid is required for all the reactions of DNA synthesis, repair and methylation , for RNA synthesis, for the metabolism of homocysteine and other important biochemical reactions, particularly during erythropoiesis, the process of formation of red blood cells, and in periods of rapid cell division.For this reason, both children and adults require folic acid to produce normal red blood cells and prevention of anemia.


Folic acid is a kind of vitamin that is water-soluble and is manufactured by bacteria found in the intestines. In pregnant women, folic acid deficiency has been pinpointed as among the causes of neural tube defects in the unborn fetus. Folic acid deficiency anemia occurs when a person requires a greater volume of folic acid, as in the case of women who are pregnant or people suffering from medical conditions like sickle cell disease. Certain medications for cancer, seizures and rheumatoid arthritis may also cause folic acid deficiency as one of their side effects.
This may indicate that the patient is suffering from a different kind of ailment that may include folic acid deficiency as one of the symptoms.
Women who reach childbearing age should also increase their intake of folic acid to prevent the incidence of birth defects during pregnancy.
But the capacity of the body to convert folic acid is limited and unmetabolised folic acid has been detected in the systemic circulation following folic acid supplement. For this reason , the deficiency of folic acid can increase preeclampsia and eclampsia , recurrent miscarriage , placental abruption , intrauterine growth retardation , low birth weight and intrauterine death .Therefore this deficiency is associated with many pregnancy complications.
Upon production, folic acid is stored within the liver for a period of time until it is released when the body needs it most. Pregnant women require double that amount, and when a woman is breastfeeding, they will need at least 1200 mcg of folic acid a day. Indeed, with a proper nutritional intake of folic acid, the presence of 5,10-optimal MTHFR protects from the risk of an incorrect development embryogenetic. This particular dosage of folic acid is recommended to all the people of childbearing age who do not apply effective contraceptive measures. On the contrary, a low intake of folic acid and consequent reduced production of the enzyme that is involved in the 5,10-MTHFR dall'dUMP proper conversion to dTMP, causes an increase in the incorporation of uracil into DNA with an increase in genomic instability . But Ddoses higher than 0.4 mg of folic acid per day may be specifically recommended only for women who have already had a child affected by defects in neural tube closure , or a family history of such malformations.



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Comments to “Folic acid deficiency anemia”

  1. Sade_Oqlan:
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  2. KOVBOY:
    Flour in many baked goods for almond flour in many vitamin E, copper, manganese, selenium, various B vitamins, phosphorous.