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Big Implications for Disease SufferersAs you might imagine, this research has profound meaning for people suffering from illnesses like cancer, AIDS, or any disease that compromises the immune system. I tried to fast for two days and made it to the 12-hour mark, which is when I broke down and ate a quart of ice cream.However, I may have to try it again, since "short-term starvation" (as scientists like to call it) might have potentially wonderful effects on one's health, from rebooting the immune system to helping chemotherapy work more effectively for cancer patients. Longo, who said that fasting encourages the human body to produce more white blood cells, which are the key to a healthy, functioning immune system.About fasting, Longo stated, "It gives the 'OK' for stem cells to go ahead and begin proliferating and rebuild the entire system. TLRs are a family of В membrane proteins that sense a wide variety of bacterial populations and activate our innate immune system.


So a connection between these front-line sensors of the immune system and whole body metabolism is well-known. The body got rid of the parts of the system that might be damaged or old, the inefficient parts, during fasting. Researchers studying TLR-2 have created knockout mice lacking TLR-2, and they discoveredВ isВ that many of TLR-2 knockout mice do not develop insulin resistance when fed with a high-fat diet.
But the bottom line again supports what has been shown in other studies: the bacteria that live in our gut are responsible for our metabolism, and it is the interaction between the bacteria and our immune system that not only protects us from pathogens, but also protects us (or not) from metabolic disease.





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