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Polycystic Kidney Disease, or PKD is disease that affects millions of people a year and currently has no cure or treatment.
Kidney stones often occur in premature infants. Some types of stones tend to run in families.
Certain kinds of stones can occur with bowel disease, ileal bypass for obesity, or renal tubule defects. There are different types of kidney stones. Calcium can combine with other substances, such as oxalate (the most common substance), phosphate, or carbonate to form the stone.

Diseases of the small intestine increase the risk of forming calcium oxalate stones. Cystine stones can form in people who have cystinuria. This disorder runs in families and affects both men and women. Struvite stones are mostly found in women who have a urinary tract infection.
These stones can grow very large and can block the kidney, ureter, or bladder. Uric acid stones are more common in men than in women. Some people might need to get fluids through a vein (intravenous). Pain relievers can help control the pain of passing the stones (renal colic). For severe pain, you may need to take narcotic pain killers or nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen. Depending on the type of stone, your doctor may prescribe medicine to decrease stone formation or help break down and remove the material that is causing the stone.

Then, the stones leave the body in the urine. Percutaneous nephrolithotomy is used for large stones in or near the kidney, or when the kidneys or surrounding areas are incorrectly formed.

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