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OHIO STATE UNIVERSITY EXTENSION Human Health Risk Assessment and Chemical Safety Stephanie Simstad The Ohio State University Extension Clermont County. OHIO STATE UNIVERSITY EXTENSION Hazard versus Risk Hazard – Potential to do harm tornado hazardous chemical Risk – Likelihood of defined harm to occur from specific hazard 1 additional cancer per 10,000 people exposed Individual Lifetime Risk of Developing Melanoma is 1 in 75.
OHIO STATE UNIVERSITY EXTENSION Risk Assessment is a 4-Part Process Hazard Identification – What chemicals are present and are they likely to be toxic? OHIO STATE UNIVERSITY EXTENSION Input for Conceptual Site Model Modified from Oak Ridge (2002) Conceptual Site Model Who may be exposed?
OHIO STATE UNIVERSITY EXTENSION Modeling of Chemicals in the Environment Chemical characteristics – More or less soluble in water?
OHIO STATE UNIVERSITY EXTENSION Exposure Assumptions Answer “how much” and “how often” people may be exposed to chemical in air, water, soil or dust Examples – How much water does an adult drink in one day? OHIO STATE UNIVERSITY EXTENSION Step #3: Toxicity Assessment What toxicity data are available? OHIO STATE UNIVERSITY EXTENSION Sensitive Subpopulations Children – Rapid development and differing physiologies of young children can result in potentially greater sensitivity to contaminants Lead exposure and the developing brain – Exposure to lead during prenatal or early childhood can cause irreversible intelligence losses – What are potential sources on the farm for lead exposure to children?

OHIO STATE UNIVERSITY EXTENSION Distinction between Cancer and Noncancer Effects Calculation of dose and some exposure assumptions differ Large number of carcinogenic contaminants are assumed to have no threshold What would dose- response curve look like if we did not assume a threshold existed? OHIO STATE UNIVERSITY EXTENSION Step #4: Risk Characterization The risk characterization combines the information obtained on toxicity with the calculated exposure to provide an estimate of risk.
President Obama issued a Presidential Memorandum directing an interagency Task Force to create a Strategy to Promote the Health of Honey Bees and Other Pollinators. November 7, 2014 presentation of a webinar on pollinators by University of Tennessee Professor of Entomology, Dr. Links from AgNIC to trade, firm, or corporation sites are for the information and convenience of users of AgNIC. Your private water well has been sampled and results show that a commonly used pesticide is present in your drinking water.
You’ve found that the family well is contaminated and you use this water for drinking, cooking, and bathing. Soil and connections to surface and ground water – Type of soil – Likely paths to and through water sources General Concept – Based on knowledge of the chemical, the soils, and local water sources; predictions can be made about how that chemical will move through the environment.

The member institutions are dedicated to enhancing collective information and services among the members and their partners for all those seeking agricultural information over the Internet.
These pages and services are the result of collaboration between the Ohio Agricultural Research and Development Center (OARDC) Library and the Ohio State Bee Lab. Whitten Building at USDA Headquarters in Washington, DC is home to approximately 40,000 Italian honey bees. Such use does not constitute an official endorsement or approval by institutions and organizations participating in the AgNIC Alliance of any product or service to the exclusion of others that may be suitable. How would you determine whether this contaminant could be a health problem for your family? This webinar will be moderated by Sallie Lee, an Urban Regional Extension Agent with the Alabama Cooperative Extension System.

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