Herpes treating cancer,remedies for cold sores on lip,herbal medicine for high blood pressure - Plans On 2016

admin | Category: Herpes Treatment Options | 28.05.2015
The study, which is published in the Journal of the National Cancer Institute, is an improved-upon version of the previous cancer-killing methods for brain tumors and is predicted to enter human trials within the next two to three years. If you’ve ever had a cold sore or fever blister, you have picked up the common viral infection known as herpes simplex.
This time around researchers decided to try mesenchymal stem cells (MSCs), a known drug vehicle that could be used to deliver the herpes virus into the glioblastoma tumors in mice. A weakness of the approach, according to the study, indicated that not all brain tumors were susceptible to the gel-intact oncolytic herpes virus. Shah predicts that after further preclinical work has been performed, herpes-loaded stem cells will become an applicable treatment for breast, lung, and skin cancer tumors that migrate to the brains. A genetically engineered herpes virus can both kill aggressive cancer cells and kick-start an immune response against them, scientists are reporting. The study found that patients with less advanced cancers had a more significant response to the viral therapy, which Harrington suggests is "encouraging" as T-VEC could play an important role as a first-line of defense against more aggressive cancer. In the two thousand and fifteenth year of our Lord, herpes will be used to treat skin cancer.
The Food and Drug Administration (FDA) in the US has just approved the herpes-happy skin cancer treatment for patients with hard-to-treat melanomas, the deadliest type of skin cancer.The drug uses a modified version of the herpes simplex virus (the type that causes mouth cold sores) to act as a kind of Trojan Horse, allowing the drugs to slip past cancer cells and destroy them. Still, all-in-all, it's a fantastic day for science, a fantastic day for cancer treatments, and a fantastic day for herpes' reputation, tbqh.
Researchers at the Harvard Stem Cell Institute (HSCI) at Massachusetts General Hospital found that by trapping herpes-loaded stem cells in a gel and applying them to tumors, they were able to significantly improve the survival rate of mice with glioblastoma multiforme brain tumors.


In past preclinical studies, oncolytic herpes simplex virus has been shown to naturally infect dividing brain cells, however it never worked well when tested on human patients. With the use of multiple imaging markers, scientists were able to watch in real time how the herpes virus passed from the stem cells to the first layer of brain tumor cells, and eventually throughout the entire tumor cells. Stem Cells Loaded With Multimechanistic Oncolytic Herpes Simplex Virus Variants for Brain Tumor Therapy. Developed by pharmaceutical company Amgen, T-Vec uses a genetically engineered virus to target and destroy cancer cells. Following the world's first investigation of viral therapy to treat skin cancer, the novel treatment was found to increase the survival of some patients by several years. It’s exciting to see the potential of viral treatment realized in a Phase III trial, and there is hope that therapies like this could be even more effective when combined with targeted cancer drugs to achieve long term control and cure,” he added.
The virus can, however, still replicate within cancer cells and destroy them by bursting them open.
And because viral treatment can target cancer cells specifically, it tends to have fewer side-effects than traditional chemotherapy or some of the other new immunotherapies,” said U.K. Researchers weren’t able to keep the herpes virus at the tumor site long enough for it to effectively kill the brain tumor, until now.
Herpes-simplex type 1 can cause break outs on the lips, tongue, or around the mouth, while herpes-simplex type 2 will cause break outs on the penis, vagina, buttocks, or anus. The gel was able to keep the stem cells alive long enough to kill any cancer cells that aren’t removed in debulking surgery, which is the surgical removal of a tumor.


The drug itself not only kills cancer cells, but also stimulates the immune system to aid in the fight.
The virus targets and destroys cancer cells because of the high levels of protein found in tumors, however, researchers have been unable to prove the therapy’s safety, which will likely be a lengthy process. Amgen will market the cancer treatment under the brand name Imlygic.Imlygic is an oncolytic (cancer-killing) drug that uses the cold sore-causing herpes virus as its base. The virus was genetically engineered to attack the rapidly-dividing cancer cells while ignoring the slow-growing healthy cells. The company also is continuing to study the treatment in combination with other immunotherapies to see if it can improve cancer survival rates. These copies multiple quickly, causing the cancer cell to burst.Amgen also removed a gene from the virus that allows it to evade detection by the host. The now very visible virus will stimulate an immune response when it begins attacking cancer cells, causing them to explode. As a result of this combination, the immune system goes into overdrive, joining the Imlygic in effectively mounting an attack against the cancer causing cells.



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Comments »

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