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admin | Category: Herpes Treatment Options | 20.04.2015
An Australian scientist who successfully invented the cervical cancer vaccine is working on new treatments for the herpes simplex virus. More than 2, 000 babies are born with a herpes infection annually, even though 40, 000 caesarians are performed due to a fear of transmitting herpes from mother to child.
While a herpes cure may be a long way off, a herpes treatment may be getting closer.  A little over 2 years ago, we wrote about Genocea's GEN-003 therapeutic vaccination. Genocea’s GEN-003 is not a herpes cure but rather a “Therapeutic Vaccination” for the moment. We update the blog every couple of weeks with news, events and other things that may be of interest.
15, 2014 (HealthDay News) – An experimental drug could eventually offer a new treatment option for genital herpes, a common and incurable sexually transmitted infection, researchers report. News about a herpes-based drug went viral after a re-engineered virus was shown in trials to nudge the immune system into attacking and killing skin cancer cells. So it’s welcome news that a study just out in the journal Science Translational Medicine describes a whole new strategy for beating down herpes viruses and keeping them down at least in mice, rabbits and guinea pigs.
We have recently extended our efforts to cure HSV infections by developing DNA editing enzymes as potential HSV treatments. The GEN-003 herpes vaccine candidate is designed to manipulate the immune responses of T cells, among other therapeutic effects.
The primary health threat posed by the herpes virus occurs when it is reactivated from its dormant state and causes both new lesions in the person who harbors the virus and in others with whom the host comes into contact. The good news is the study is still going on and Genocea has updated their website with some promising information. The treatment of individuals infected with the herpes simplex virus depends on several factors.
Scientists have developed a novel treatment approach for persistent viral infections such as herpes.


We have a very promising new candidate for herpes, says William Jacobs, an HHMI investigator at the Albert Einstein College of Medicine, but this might also be a good candidate as a vaccine vector for other mucosal diseases, particularly HIV and tuberculosis.
One approach that might cure herpes, however, is to disrupt the silencing mechanism harbored in the host’s neurons. In an effort to find a cure for herpes, Genocea has received a lot of attention with its GEN-003 vaccine and clinical trials.
The Company had commenced clinical testing in the UK with its vaccine candidate for the prevention and potentially the treatment of genital herpes. Many people choose to treat herpes simplex because treatment can relieve symptoms and shorten an outbreak. An experimental treatment using a genetically engineered herpes virus appears to be effective in treating one of the most common, deadly, and increasingly expensive cancers: melanoma.
Using animal models of herpes simplex virus (HSV) infection, researchers show that blocking the activity of a host cell protein called LSD1 reduces HSV infection, shedding (release of viral particles) and recurrence.
Manuka Honey from New Zealand is a specific type of honey that has actually been approved for use as a medical device, due to its healing properties and superior potency. Cough treatments could change dramatically after the herpes virus helped researchers discover that the respiratory tract links to two different parts of the nervous system. Cancer Therapies at The Institute of Cancer Research and head of the trial, has been working on this particular virus for about a decade.
But now, newly published findings suggest one of the most promising experimental herpes- treatments in decades can significantly reduce the virus’ ability to replicate and spread, and do so without the side-effects of current therapies. In February 2014, it was announced that Frazer’s new vaccine against genital herpes has passed human safety trials in a trial of 20 Australians. A fish processor’s healed hand warts has alerted scientists to the herpes-fighting properties of the blue blood of the Tasmanian blacklip abalone. Big pharma dabbled in developing a genital herpes vaccine, but GlaxoSmithKline was particularly noteworthy for its epic flop compared to controls, it actually caused even worse outbreaks in the women studied in a huge Phase III study.


One of the most common questions asked of doctors who treat genital herpes comes from couples in which one partner is infected with the virus and the other is not. HHMI’s Albert Einstein College of Medicine scientists recently found a new way to treat the herpes virus. Genetically engineering the herpes virus so that it attacks skin cancer cells has potentially cured some patients, scientists have said. HIV Integrase inhibitors that are used for the treatment of HIV were shown by researchers in the Knipe lab to also inhibit HSV-1 replication in cell based assays with high efficacy.
Cancer Research in the UK, scientists showed that the new treatment allowed some patients with skin cancer to live for more than three years the benchmark many oncologists use to define a cure. Of the 26 per cent of patients who responded to the herpes virus treatment, known as T-Vec, one in ten saw their tumours vanish completely. A new drug appears to combat the virus that causes genital herpes, suggesting it could one day be used as a treatment for people with the condition, according to a new study. Most herpes medication works to manage the symptoms, but the anti-viral properties found in abalone act as a preventative measure. A genetically modified strain of herpes can kill cancer cells and stop tumors from growing, according to new research. A clinical trial seeking patients for a research study for the treatment of GENITAL HERPES.




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Comments »

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