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The researchers reviewed prior studies examining the link between diabetes and hearing loss. However, Helzner added, the association between diabetes and hearing impairment tends to be stronger in studies that included younger participants. Both high and low frequency hearing impairment have been linked with sleep apnea in a new study of nearly 14,000 individuals. Hearing loss is linked with accelerated cognitive decline in older adults, but the use of hearing aids may help safeguard seniors' memory and thinking skills. The significant role of beta cell 'hubs' in the pancreas has been demonstrated for the first time, suggesting that diabetes may due to the failure of a privileged few cells, rather than the behaviour of all cells.
At first, although the pancreas makes more insulin to try to get glucose into the cells, it cannot keep up, and the sugar builds up in your blood instead. Genes: In DNA, scientists have found little bit of different that impact your body makes insulin. Extra weight: Insulin resistance can be caused by obesity or obese, especially when your extra pounds are around the middle. Metabolic syndrome: High blood glucose, extra fat around the waist, high blood pressure and high cholesterol and triglycerides are a group of conditions to make insulin resistance for people.
Your liver have too much glucose: If your blood sugar is low, your liver will make and send out glucose.
Between cells are bad communication: If your cells send the wrong signals or do not pick up messages correctly, your cells will make and use insulin or glucose. Broken beta cells: the cells can be damaged by high blood glucose or when the cells make the insulin send out the wrong amount of insulin at the wrong time, then your blood sugar gets thrown off, too. Random plasma glucose (type 2) the random plasma glucose test measures plasma, or blood, glucose levels.
Type 2 diabetes is a condition, marked by high blood sugar (which doctors refer to as hyperglycemia), and is on the rise worldwide.. A new study by Dutch researchers appears to show that an underactive thyroid, or hypothyroidism, could put you at a greater risk of type 2 diabetes even for those who take medication in order to keep hormone levels withing normal ranges. The study, which has not been published in a peer-review journal but presented at a medical conference, was undertaken over eight years and led by Dr. Diabetes is a massive health problem that causes blood glucose levels to rise to an unhealthy level which is defined as hyperglycemia.
The average age of the participants in the 8-year-old study was 65 and each was given a blood test to measure blood sugar levels and thyroid function. The researchers found that those who suffered from hypothyroidism risked getting type 2 diabetes 13% more often than those with thyroids that weren’t underperfoming. While the researchers admit that they didn’t find a direct link between hypothyroidism and type 2 diabetes, they certainly have found an association.
The study was presented yesterday at the Endocrine Society’s annual conference in Boston.
While it’s gotten better in recent years, type 2 diabetes early in the 21st century was beginning to look like a new epidemic especially in the United States. This article is NOT an investment recommendation, please see our disclaimer - Get our 10 free in-depth ebooks on famous investors here, Got a tip on hedge funds, banks or related? While studying economics, Brendan found himself comfortably falling down the rabbit hole of restaurant work, ultimately opening a consulting business and working as a private wine buyer.
As we predicted last December, 2015 saw the release of the Dexcom G4 Platinum with Share receiver, the Tandem t:slim G4 insulin pump, the Dexcom G5 Continuous Glucose Monitoring System, the Medtronic 640G with SmartGuard in Europe, and two novel new insulins (both from Sanofi) – Afrezza inhalable short-acting and Toujeo basal insulin.
Looking ahead to 2016, we’re optimistic about these seven diabetes products potentially hitting the market in the next 12 months.


At the ADA Scientific Sessions in Boston this June, Insulet teased the crowd with a first look at the next generation controller for their popular patch insulin pump, the Phoenix PDM (Personal Diabetes Manager). The Freestyle Libre (consumer version) and Libre Pro (professional HCP-use version) might flash their way stateside in 2016. Libre’s appearance in the Freestyle pipeline follows Abbott’s long commitment toward out-of-the-box calibration and this author believes it serves as an important proof of concept toward their next generation continuous glucose sensors. While Abbott has been tight-lipped about progress to bring Libre to the United States, we do know that the Libre Pro has been submitted to the FDA for potential launch in 2016. The Minimed 640G insulin pump may come to the States by end-of-year 2016, as Medtronic says they plan to submit to FDA early in the new year. The pivotal trial in the States was completed with Medtronic’s fourth generation sensor (the third in the Enlite series) and they submitted specs to the FCC in February for a transmitter designed specifically for the 600 series pumps (of which 670G will be the next in their pipeline), so we expect to see Medtronic skip the Enlite 2 here in the U.S.
It wouldn’t be the end of a fiscal year without some speculation on what Dexcom has up its sleeves. Still, we know that Dexcom surprises even themselves with how quickly they can get product approved and rolled out to customers, with the original G4 Platinum approved within 90 days of submission to FDA.
Novo Nordisk has another game-changer up its sleeve, as well, having announced just last week that an NDA has been filed for a newer, speedier version of Novolog (insulin aspart) for treatment of type 1 and type 2 diabetes. Another insulin coming to us in 2016 is Lilly’s new basal insulin, Basaglar – a form of insulin glargine (which you may recognize if you’re familiar with Lantus).
In October, we were thrilled to learn that Eli Lilly & Company acquired the rights to Montreal-based Locemia’s novel nasal glucagon. So other than the omnipod is there any other tubeless insulin pump on the market right now? The Diabetes Media Foundation is a 501(c)(3) tax-exempt nonprofit media organization devoted to informing, educating, and generating community around living a healthy life with diabetes. Statistics diabetes: american diabetes association®, Statistics about diabetes overall numbers diabetes and prediabetes.
However, further research is needed to confirm this connection, said the team at the State University of New York Downstate Medical Center in New York City. It's possible that in older patients, other causes of age-related hearing impairment may mask the contribution of diabetes, she said.
When you eat, your blood sugar goes up, and usually the liver will slow down and store its glucose for later. And overactive thyroid will speed up your metabolism but is not necessarily a good thing while a thyroid that is underactive will not produce enough hormones and will slow down metabolism which often leads to weight gain. There medical records were also studied and new blood work was done every couple of years as the researchers looked for the onset of type 2 diabetes. Those with prediabetes and were showing hypothyroidism faced a 40% greater risk of full-blown type 2 diabetes. On a whim, he moved to China, and in his first week following a triumphant pub quiz victory, he found himself bleeding on the floor based on his arrogance. Also launched in 2015 were Eli Lilly’s Trulicity GLP-1 agonist and Novo Nordisk’s Tresiba basal insulin.
The chunky plastic PDM controllers we saw in the UST200 and UST400 models will give way to a sleek, sexy color touchscreen interface. The first of its kind, the Libre is a factory-calibrated flash system, which means that, rather than continuous display of interstitial glucose readings, the user wears a small sensor in the skin beneath a flat, round, white, disc-shaped transmitter and carries (in the consumer version) a small device that the person can use to scan the sensor and display a reading at any time.
The Pro version is meant to be used by health care providers to collect glucose data – which is blinded to the patient – for analysis and treatment changes and would have an easier pathway for reimbursement than the consumer version. This is the most revolutionary change in design we’ve seen from Medtronic, with a whole new colored user interface, new buttons, and a portrait orientation – shifting the long-standing insulin pump paradigm from pager to smartphone.


If 2015 was the year of the Dex – with two integrated pump partners (Tandem and Animas) and two new products (G4 Platinum with Share and G5), then 2016 is going to be about their building capacity for what’s to come.
In the meantime, we expect to see a new insertion device for their sensors and hope to learn more about the G5 strengths and opportunities as the long line of customers waiting for Santa Claus to bring them their G5 systems unwrap those tech goodies. Sanofi filed for New Drug Appliaction (NDA) with FDA for its GLP-1 agonist Lyxumia (lixisenatide) in September 2015.
Novo Nordisk’s Xultophy, a combination of their commercially successful GLP-1 agonist Victoza and their brand new basal insulin Tresiba, also had its NDA put in front of FDA in September and will likely beat Lixilan to market. According to their press release, the “faster-acting insulin aspart contains a short-acting insulin and two well-known excipients, a vitamin and an amino acid, to increase the initial absorption rate and an earlier blood sugar lowering effect.” What does this mean for people with diabetes? Easy to carry, easy to dose, easy to implement, nasal glucagon will do for people with diabetes what the Auvi-Q has done for people with allergies – make a life-saving, every-second-counts emergency treatment fairly fool-proof to administer. I love my G5 and need to replace my old Minimed with something that has G5 integration as soon as a pump comes on the market that allows that. Although people with type 2 diabetes make insulin, their cells do not use it as well as they should.
The study involved over 8,000 people and the results seems to show a fairly convincing link between hypothyroidism and type 2 diabetes. This insulin resistance will generally make your pancreas increase production of insulin but over time it just can’t keep up and those with type 2 diabetes are often forced to add additional insulin either orally or through injections. The same man who put him there offered him a job lecturing for the University of Wales in various sister universities throughout the Middle Kingdom.
As for Libre for home use, we’re still betting here on 2017, though the pivotal study of Libre in the United States was completed in March 2015. Xultophy is already approved in Europe, but was held up here until its Tresiba component could be approved.
As stated in the FDA press release, “Basaglar is the first insulin product approved through an abbreviated approval pathway” because it is “sufficiently similar to Lantus to justify reliance.” Lantus’s patent expired in 2015 and it will be interesting to watch glargine’s progress under a competing label. Locemia had said they planned to submit to FDA in late 2015, early 2016, so it’s our best guess that Lilly might follow a similar timeline. And another 86 million was in type prediabetes: It mean that glucose in their blood is not normal, but not high enough to be diabetes yet. While primarily lecturing in descriptive and comparative statistics, Brendan simultaneously earned an Msc in Banking and International Finance from the University of Wales-Bangor. Though the Phoenix will be Bluetooth-enabled, this PDM will not yet be integrated with the Dexcom G5, though we should see that product quickly on its coattails given that value-added capability.
Abbott has not historically had the kind of smooth, fast-track relationship with FDA that companies like Dexcom have mastered. We expect to see all three of these GLP-1 drugs available in pharmacies by next year’s end.
Another note of interest is that Basaglar is not approved as a biosimilar product, as the manufacturer must actually apply for biosimilarity through a specific application process.
As Merck and other companies prepare for a rollout of their own forms of insulin glargine in the coming years, we hope that choice in basal insulin therapy will increase for patients and that prices…perhaps…decrease.
I just wish tandem would get the dual chamber pump out so people can have better control of there sugars.



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