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The pancreas has many islets that contain insulin-producing beta cells and glucagon-producing alpha cells. Since diabetes is a disease that affects your body's ability to use glucose, let's start by looking at what glucose is and how your body controls it.
When you eat food, glucose gets absorbed from your intestines and distributed by the bloodstream to all of the cells in your body. To maintain a constant blood-glucose level, your body relies on two hormones produced in the pancreas that have opposite actions: insulin and glucagon.
Insulin is made and secreted by the beta cells of the pancreatic islets, small islands of endocrine cells in the pancreas. As such, insulin stores nutrients right after a meal by reducing the concentrations of glucose, fatty acids and amino acids in the bloodstream.
Blood tests for Lyme disease are the usual way of confirming a diagnosis based on symptom history and clinical signs.
Patients who undergo a blood test for Lyme disease fairly rapidly after a tick bite may require another test at a later date if the first is negative but the symptoms persist. A blood test for Lyme disease may be accompanied, or even replaced, by antibody testing of a patient’s cerebrospinal fluid in cases where central nervous system dysfunction is observed.
Blood tests for Lyme disease are the main way in which the condition is diagnosed but many patients struggle to convince their physician of the need for such tests, especially in states (or countries) where Lyme disease is not considered to be a problem. Following treatment for Lyme disease, and co-infections in some cases, patients will likely undergo another blood test to assess the presence of antibodies to Borrelia.
Introduction: Type 2 Diabetes is a lifestyle related disease and a major risk factor for Cardio Vascular Diseases (CVDs). Objectives: To estimate the prevalence of Type 2 Diabetes and Prediabetes among adults (aged 30 years and above) residing in Neyyattinkara taluk of South Kerala and to identify the diabetes Case Detection Rates across different age groups.
Whereas rest of India is still grappling with communicable diseases and malnourishment, the state of Kerala stands out, with non-communicable diseases (NCDs) emerging as a major public health challenge.

To estimate the prevalence of Type 2 Diabetes and Prediabetes among adults (aged 30 years and above) residing in Neyyattinkara taluk of South Kerala. To study the fasting plasma glucose levels as an indicator of diabetes control in the community. Data Collection Tools: Structured questionnaire and Blood Sugar examination using Glucometer (DiabeCHECK- Jitron).
Ethical clearance was obtained from Institutional Ethical Committee, Trivandrum Medical College.
Diabetes Case Detection Rates across different age groups were examined and was highest (76%) between 60 and 69 years.
81 (18%) persons had blood sugar values above 125 mg%.  Of these 42 were already diagnosed and was on treatment.
A national study9 to determine the prevalence of Diabetes and Prediabetes in India done in three states (Tamil Nadu, Maharashtra and Jharkhand) and one union territory (Chandigarh) showed that the weighted prevalence of Diabetes was 10.4% in Tamil Nadu, 8.
Studies from Kerala  also emphasized the need for life style modifications and community based programmes for early detection and preventive measures.1, 12  Diabetes Case Detection Rate in the present study was 50% in persons less than 50 years of age and more than 75% above the age of 50 years.
Prediabetes is a significant risk factor for the development of type 2 diabetes, micro vascular, and macro vascular disease. Your body tries to keep a constant supply of glucose for your cells by maintaining a constant glucose concentration in your blood -- otherwise, your cells would have more than enough glucose right after a meal and starve in between meals and overnight. A very limited number of published studies indicate high prevalence of Type 2 Diabetes in the state of Kerala. Ltd).  Calibration was done daily to ensure reliability and new pairs of DC cells were used every day.
All Prediabetic were educated regarding lifestyle modifications for Diabetes prevention and motivated to follow up in local Primary Health Centres. Lifestyle change in Kerala, India: needs assessment and planning for a community-based diabetes prevention trial.

Report of the Committee on the classification and diagnostic criteria of diabetes mellitus.
Evaluation of non communicable disease control pilot programme of National Rural Health Mission in Thiruvananthapuram district. High prevalence of type 2 diabetes mellitus and other metabolic disorders in rural Central Kerala. Prevalence and risk factors of diabetes in a community-based study in North India: the Chandigarh Urban Diabetes Study (CUDS). Cluster randomised controlled trial of a peer-led lifestyle intervention program: study protocol for the Kerala diabetes prevention program.
Screening Performance of Diabetes Risk Scores Among Asians and Whites in Rural Kerala, India.
The cells take in glucose from the blood and break it down for energy (some cells, like brain cells and red blood cells, rely solely on glucose for fuel). So, when you have an oversupply of glucose, your body stores the excess in the liver and muscles by making glycogen, long chains of glucose.
Insulin is required by almost all of the body's cells, but its major targets are liver cells, fat cells and muscle cells.
This study was done in the Neyyattinkara taluk of south Kerala by including coastal, mid land and high land regions to make it representative of the geographical profile of the state. This is one of the criticism against such Lyme disease blood tests as only unbound antibodies are detectable by ELISA and Western Blot, thus complicating assumptions regarding the implications of high or low levels and the actual presence of bacteria at the time of the Lyme disease blood test.

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