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Adding a second antihypertensive medication appears to be more beneficial than increasing the dose of a single antihypertensive in reducing all-cause mortality cardiovascular outcomes in patients with cardiovascular disease (CVD).

This entry was posted in Cardiovascular Disease, Geriatrics, Hypertension, Non-Communicable Disease, Non-Communicable Disease Featured 2, Pharmacology, Primary Care and tagged angiotensin receptor blocker, antihypertensive, antihypertensive combination therapy, antihypertensive monotherapy, ARB, calcium channel blocker, cardiovascular disease, CCB, CVD, diabetes, diabetes mellitus, geriatrics, high blood pressure, hypertension, olmesartan, pharmacology, primary care, type 2 diabetes. This was the main finding of a recent randomized trial that sought to determine the efficacy of high-dose angiotensin receptor blocker (ARB) therapy vs the addition of a calcium channel blocker (CCB) to a standard dose ARB in patients with CVD or type 2 diabetes.

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