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Diabetes mellitus is not one disease, but rather is a heterogeneous group of multifactorial, polygenic syndromes characterized by an elevation of fasting blood glucose that is caused by a relative or absolute deficiency in insulin. The American Diabetes Association (ADA) recognizes four clinical classifications of diabetes: type 1 diabetes (formerly, insulin dependent diabetes mellitus), type 2 diabetes (formerly, non-insulin dependent diabetes mellitus), gestational diabetes, and diabetes due to other causes (for example, genetic defects or medications). Type 1 diabetics must rely on exogenous insulin injected subcutaneously to control hyperglycemia and ketoacidosis. The goal in treating type 2 diabetes is to maintain blood glucose concentrations within normal limits, and to prevent the development of long-term complications.
Gestational diabetes is defined as carbohydrate intolerance with onset or first recognition during pregnancy. ReferenceInternational Diabetes Federation, Lippincott Illustrated Reviews Pharmacology & Biochemistry, American Diabetes Association, National Diabetes Education Program USA, Mayo Clinic. Thankfulness to my father who shared with me regarding this web site, this website is in fact remarkable. Do you find it impossible to lose weight and keep it off despite your best efforts to diet? If you answered 'yes' to any of the above, and you're dreading starting another well-intentioned New Year weight loss programme that you know is doomed to failure almost before it's started - don't despair.
The good news is that medical research now appears to confirm that your weight gain may not be your fault at all, but a problem with your metabolism.
Starting today in our exclusive four-part diet series, we outline the Metabolism Miracle - a revolutionary new weight loss programme written by respected U.S. Kress explains: 'Traditionally, weight loss programmes have been built on the assumption that everyone's metabolism works in the same way. According to Kress, recent medical studies and her experience of dealing with clients with weight problems suggest that almost 50 per cent of people unwittingly suffer from this alternative metabolism - what she calls Metabolism B (which can also be known as metabolic syndrome, syndrome X and insulin resistance).
It's an inherited condition that sends appetite spinning out of your control and causes your body to 'over-process' carbohydrate foods, turning them into excess body fat in the blink of an eye - no matter how hard you diet or exercise.
If you crave carbohydrates, struggle to control your appetite, feel tired, anxious and depressed - then in all probability your weight gain is not your fault at all. The Metabolism Miracle has already changed the lives of thousands of Americans, and now it can change yours, too. But at the root of all these problems experienced by the Metabolism B sufferer is the chaotic way their body processes carbohydrates and, in particular, the way the pancreas releases the hormone insulin, which is needed to balance blood sugar.
Anyone with a 'normal' metabolism can eat, for example, a sandwich (which contains plenty of carbohydrate in the form of bread) and feel full and energetic for four or five hours afterwards. A person with Metabolism B, however, will find themselves craving a chocolate bar within an hour or so of eating the same sandwich.
This is because when they eat carbohydrates, their body tends to release too much insulin - which leads to see- sawing blood sugar levels, fatigue and an urgent craving for yet more carb-loaded food.
You may be saying at this point that you can't have Metabolism B because, for example, up until a year ago or so, you were able to control your weight with no problem.
But Metabolism B is an inherited predisposition that can lurk for years before making itself known. Some people who have it may show symptoms as children, while others won't see the signs until their teens or even later in life. Metabolism B is sometimes only 'switched on' by an outside trigger such as stress, inactivity, illness or a hormonal change in the body. However, the good news is that if you follow the Metabolism Miracle diet, you can switch off the Metabolism B rollercoaster, gain control of your appetite and lose all the weight you want to. We've established that the reason people with Metabolism B struggle with their appetite and weight is because their bodies release too much insulin when they eat carbohydrates - throwing their blood sugar out of kilter and instructing their brains to crave more carbohydrates to try to rebalance things. The human body has a built-in survival mechanism that only serves to add to the weight loss challenges of people with Metabolism B.
Anyone with a normal metabolism who goes for long periods without food will release the right amount of glycogen to keep their body going - but not you. If you have Metabolism B, your body releases too much insulin - which, in turn, stimulates the glycogen from your liver to move out of your bloodstream into your fat cells. You are developing a paunch, your blood pressure and cholesterol may be rising and you even risk crossing the boundary into the tricky waters of diabetes.
You constantly struggle with bouts of low blood sugar that have turned you into a carbohydrate addict. It may not seem fair, but your condition will increase your appetite, weight and related health problems while wreaking havoc on your life. It is a simple three-step approach that combats your body's overactive response to carbohydrate intake and trains it to handle carbohydrates normally.
Once you learn to live in balance with your metabolism, your weight will come off - and stay off. There will be no more carb cravings, energy slumps, food binges or frustrating weight regain. Miraculously, you will begin to feel the effects of this new approach in less than one week. Although you will still be eating many of your favourite foods in this easy, straightforward part of the diet, you will, in essence, be cleaning up the metabolic mess you are currently in.
As a result, your fat cells will shrink and you will lose weight - most noticeably, the roll of fat around your tummy will diminish dramatically. As it turns out, temporarily eliminating most carbohydrates from the diet is the only drug-free way to control the blood glucose imbalance that plagues people with this alternative metabolism.
As a result, for the first eight weeks of step one, your blood sugar will run smoothly, with no spikes to stimulate the over-release of insulin that encourage your body to lay down those fat stores.


Don't worry - carbs will come back into the picture in steps two and three of the diet, which we'll outline later in this series, and, by then, you will have established a new metabolic balance that your body can work with. Perhaps the best part about step one of the Metabolism Miracle, besides the fat loss and energy boost it promises, is its ease and simplicity. During the eight weeks of step one, you may eat liberally from the first three arrows, but you must avoid the foods in the carbohydrate arrow. Although most foods contain a combination of nutrients, they are classified into their arrow by the main nutrient that they contain. THE RULESYou can eat as much of the allowed foods as you like - but obviously, huge portions will thwart your weight loss.
Many people are surprised to learn that milk, fruit, carrots and lentils also fit into the carbohydrate arrow.
Foods in the carb arrow will have a dramatic impact on blood sugar and cause your body to quickly release insulin, which is why you must avoid these foods during step one - don't be tempted to have even the tiniest amount. The great news is there is no need to weigh, measure or count foods from the lean protein, healthy fat and vegetable arrows. For ease, it is probably best to eat your carbs at mealtimes rather than snack times, so you can be sure of leaving a five- hour gap between them. To calculate a food's net carbs, look under the nutritional values per serving size on the packaging, and subtract the dietary fibre figure from the total carbohydrate grams. Your strong reaction to this list of foods is just one more affirmation that you have Metabolism B. However, you should know that every one of my patients who completed the first three days of step one completed the remainder of the eight weeks.
Although you will be delighted with the changes that your body feels by the fourth day of this diet, the first three days of Step One will be tough. SnacksHere are some non- carb snacks that will stop you feeling hungry between meals, without breaking the rules.
Divide the grated reduced-fat cheese and chopped turkey bacon equally between the four cups.
Spoon individual teaspoonfuls of batter on to the prepared hot pan to create small pancakes.
Stir the cream into the saucepan that the chicken was cooked in and add enough chicken broth to make a sauce.
Adapted from THE METABOLISM MIRACLE by Diane Kress, published by Da Capo Books, a division of Perseus on February 4 at A?14.99. I wrote yesterday about the Skinny on Being Thin and how people who are underweight or thin are not necessarily happy about being thin and don't always appreciate drawing attention to their weight. As the fastest growing consumer health information site a€” with 65 million monthly visitors a€” Healthlinea€™s mission is to be your most trusted ally in your pursuit of health and well-being. For example, it is estimated that more than 250 million people worldwide are afflicted with diabetes, and the prevalence is expected to exceed 350 million by the year 2030. Diabetes is the leading cause of adult blindness and amputation, and a major cause of renal failure, nerve damage, heart attacks, and stroke.
The disease is characterized by an absolute deficiency of insulin caused by an autoimmune attack on the ? cells of the pancreas. The goal in administering insulin to Type 1 diabetics is to maintain blood glucose concentrations as close to normal as possible and to avoid wide swings in glucose levels that may contribute to long-term complications. Insulin may also be delivered by a pump, which allows continuous subcutaneous infusion of insulin 24 hours a day at preset levels and the ability to program doses (a bolus) of insulin as needed at meal times.
Weight reduction, exercise, and medical nutrition therapy (dietary modifications) often correct the hyperglycemia of newly diagnosed type 2 diabetes. It is important to maintain adequate glycemic control during pregnancy, because uncontrolled gestational diabetes can lead to fetal macrosomia (abnormally large body) and shoulder dystocia (difficult delivery), as well as neonatal hypoglycemia.
A team of inspired pharmacists is working to build a free access pharma publication, we call it Pharma Mirror.
Pharma Mirror has an International Standard Serial Number ISSN 2219-763X of its own and it has been assigned by ISSN Center, Paris. Even better, there is a new way - finally - to do something about those unwanted inches that will work for you where all other diets have failed.
That if you monitor your calories, count fat grams, drink meal replacements, or follow the diet sheet - whoever you are, you will lose weight.
Read on to discover the diet miracle that really can improve the way you look and feel within days. This is because when they eat carbohydrates, their body releases insulin in the correct amount, at the correct time for optimal metabolism and energy. So if you have suddenly found you can't control your weight when you never had a problem before, this could be why.
When blood sugar drops to the low end of normal and you choose not to eat, your liver can 'feed' the body.
Well, each time you eat carbohydrates, your body can run on that blood sugar for about five hours. Due to this 'hyper-insulin' response, you feel exhausted and irritable because your blood sugar levels are never constant. Your health will improve, your energy level will soar and you'll experience a feeling of peace and contentment.
It's a low-carb 'rehab' period that's specifically designed to reprogramme your body to handle carbohydrates healthily.
For the eight weeks of step one, you will need to cut out most carbohydrates from your diet. By eliminating carb-dense foods, you stop contributing too much sugar to your bloodstream, which helps to stop your body releasing too much insulin.


The temporary elimination of most carbs will enable the liver to deplete most of the glycogen stores it uses for the self-feeding mechanism.
For example, steak and chicken fall into the protein arrow, olive oil and nuts fall into the fat arrow, and potatoes fall into the carbohydrate arrow. During any five-hour period of step one, you may eat no more than 5g of carbohydrate in total. The list of carbohydrates that you must absolutely avoid during step one all exceed the 5g limit (see the arrow chart). I call these foods '5x5 carbs' because you can tally their carbohydrate total with a quick, easy formula to decide if they fit the 5x5 rule. YOU CAN DO ITAlmost every patient with Metabolism B in my practice who sees the 'carbs to avoid' list begins to panic. Continue to cook until the chicken is tender, about 15 more minutes, adding chicken broth as needed to maintain the level of liquid during the cooking process. Both of which will support, guide, and inspire you toward the best possible health outcomes for you and your family. Insulin resistance is the decreased ability of target tissues, such as liver, adipose tissue, and muscle, to respond properly to normal (or elevated) circulating concentrations of insulin. In the absence of a defect in ?-cell function, non -diabetic, obese individuals can compensate for insulin resistance with elevated levels of insulin. Hypoglycemic agents or insulin therapy may be required to achieve satisfactory plasma glucose levels. Do you struggle to resist carbohydrate foods such as bread, cakes, chocolate, crisps and pasta? WHAT EXACTLY IS METABOLISM B?There are a host of symptoms related to Metabolism B, as you will see when you work through the questionnaire on the right - including uncontrollable weight gain, a spongy roll of fat around your tummy and lack of energy. If you choose not to eat within five hours, your liver will automatically release stored blood sugar called glycogen to push blood sugar levels back into the normal range. You'll need to check the labels on the packaging to see how much carbohydrate they contain.
This '5x5 rule' allows you to eat limited amount of carbs without stimulating insulin release. In a mixing bowl, blend together the ricotta cheese, soy flour, rapeseed oil, vanilla, Splenda and salt.
The metabolic abnormalities of type 1 diabetes mellitus include hyperglycemia, ketoacidosis, and hyper triacylglycerolemia. They result from a deficiency of insulin and a relative excess of glucagon.
Glyburide and metformin may be reasonably safe alternatives to insulin therapy for gestational diabetes. EnjoyIf you enjoyed this post, please consider subscribing to the RSS feed to have future articles delivered to your email inbox or feed reader. I felt that there was something wrong with removing an entire group of nutrients from the daily diet. Low-fat yoghurt contains protein and fat, too - however its main nutrient is carbohydrate, so this dairy product is in the carbohydrate arrow. Rather, type 2 diabetes develops in insulin-resistant individuals who also show impaired ?-cell function. However, larger randomized studies are needed to fully assess neonatal outcomes and optimal dosing regimens. Add the chicken, green pepper, paprika and stock to the saucepan and cook for 30 minutes over a low heat. The metabolic alterations observed in type 2 diabetes are milder than those described for the insulin-dependent form of the disease, in part, because insulin secretion in type 2 diabetes- although not adequate- does restrain ketogenesis and blunts the development of diabetic ketoacidosis.
Even though you will be eating plenty of food for the first three days, you can expect to feel tired, grumpy, hungry, slightly shaky, light-headed and a little headachy.
Available treatments for diabetes moderate the hyperglycemia, but fail to completely normalize metabolism. The long standing elevation of blood glucose is associated with the chronic complications of diabetes- premature atherosclerosis, retinopathy, nephropathy, and neuropathy.
After three days, I promise you will begin to feel much better, and following the diet will become easier. The problem is that your liver contains a stockpile of blood sugar in the form of glycogen.
When you begin Step One and cut out dense carbohydrate from your diet, your liver will automatically 'feed' you with a meal's worth of glycogen from its stores, a process it will repeat about every five hours. In response to this, your pancreas will release too much insulin and your blood sugar will continue to rollercoaster, even though you will be eating minimal carbohydrates. After three days, as you continue to eliminate a large amount of carbohydrate from your diet and your liver remains purposely depleted of most of its glycogen stores, your brain will have to come up with an alternative plan for fuelling your body. Now for the good news: if you follow my plan, the choice it will make will be to burn fat cells.
Exercise plays an important role in the Metabolism Miracle now as it literally energises and activates muscle.



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