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It has become increasingly appreciated since this discovery that the role of our immune system is not simply to ward off unwanted bacteria and pathogens, but also to learn to accept and tolerate the commensal and symbiotic organisms of the human biome that are non-self but that we depend upon to function. Helminth worms have been present in the intestines of vertebrates since long before the evolution of homo sapiens.
Over the same time period, immune dysfunction has become an epidemic in the developed world.
By contrast incidence of immune dysfunction in the developing world has remained minimal and static, just as it was in the industrialized world a mere 100 years ago.
Additionally, migration studies have shown that recently arrived immigrants into the developed world who have had no previous history of immune dysfunction are likely to develop immune disorders in relation to the length of time since arrival, and their offspring go on to experience equal incidence of immune dysfunction as natives of the host nation.
Modern sanitized living has massively reduced the number and variety of organisms living within us with whom we have evolved to coexist. The obvious answer is to replace the helminth worms that our bodies are lacking in order to redress the balance.

Here at Wormswell we want make the incredible immunoregulatory powers of the hookworm accessible and affordable.
The oldest known evidence of a helminth colonization has been found in a 270 million year old shark coprolite from the Paleozoic period.
It is estimated that  2 billion people are currently playing host to at least one helminth species and approximately three quarters of a billion people are carrying hookworms. Recent history however has seen the introduction of modern sewerage systems and medical advances which have all but eradicated hookworms in post industrial westernised society in the space of just a few generations. This observation rules out the possibility that the cause is purely genetic and suggests environment as the major factor. If we can allow their influence to gently rein in and modulate our over-active and misdirected immune systems, we can once again achieve the equilibrium that has been lost due to modern living conditions. Hookworms can gently and safely modulate an out of control immune system so that sufferers of many allergic, inflammatory and autoimmune conditions can achieve relief from their symptoms and become less reliant on conventional pharmaceutical drugs.

Given that humans are estimated to have first walked the earth a mere 200,000 years ago, it would safe to assume that helminth worms have been our companions since the very birth of humanity. In Europe the rate of allergy is increasing by 5% every year and it was estimated that in 2015 one half of the entire European population suffered from at least one allergy.
These organisms are seen as necessary to regulate the body’s immune system and without them incidence of immune dysfunction and allergic and inflammatory disease has increased to epidemic proportions.

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