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The international guidelines for the management of diabetes mellitus (type 2 diabetes) put into consideration factors such as age, social environment, the duration of the illness and associated health complaints.
According to the researchers from the Medical University of Vienna in Austria, gender is becoming an ever-growing issue, as men and women bear different risks and fall victim to or suffer from a different type of diabetes. For this reason, the researchers put forth that diabetes treatment should be more personalized and more gender-specific.
From a biological aspect, the researchers said that men are principally at a higher risk of developing type 2 diabetes than women. Men are most at risk because they have a greater amount of stomach fat and more liver fat, as well as a lower sensitivity to insulin regardless of whether or not they are overweight. Men, on the other hand, are more at risk of developing diabetes at a later point in life, the researchers said. According to the researchers, there are also gender-specific biomarkers, which helps detect diabetes risks early on. The researchers found that synthetically manufactured substances such as Bisphenol A or Phatalate - risk factors for diabetes - have different effects in men and women. According to the researchers, the mentioned gender-specific factors in diabetes should be incorporated in the guidelines. Special foam inserts are easily available without the prescription of a trained medical professional. One can develop a diabetic neuropathic condition where the person becomes unaware of the feelings in his legs and feet.
As a normal person would have become aware of the bruises or cuts on the legs, a diabetic person cannot sense the same. The condition of gangrene is a serious one, primarily marked by loss of adequate supply of blood to the tissues of the body, ultimately resulting in its necrosis or death. Injury to the tissues, infection (mostly of bacterial origin) and presence of any underlying health ailment that inflicts damage to the blood carrying vessel structure form the three key underlying mechanisms that are responsible for initiation and development of irreversible tissue damage and life threatening condition of gangrene.


As already explained, one of the causes of gangrene in the toes and fingers is linked with damaged blood vessels. High level of blood glucose associated with diabetes mellitus also damages the nerves (known as peripheral neuropathy), especially the nerves in the lower extremities. The dullness or lack of sensation puts diabetic individuals at an increased risk of injuring the skin of their fingers or feet without having any realization (it mostly goes unnoticed in the feet region). The sore or foot ulcer formed takes an extended time to heal because of both, poor circulation of blood through the injured area as well as lesser number of defence cells. Bacterial infection also forms another causative factor that makes the diabetic individual more prone to developing gangrene. Such type of infection is marked by noticeable skin discolouration and dryness along with the formation of skin blisters. The weakened immune system (seen in diabetes) further raises the risk of incurring serious infection, which later develops, into gangrene. A 28-year-old unmarried man was dating widely, but always wore a condom during intercourse.
Women are "protected" for a while due to increased production of the estrogen hormone, until menopause causes hormonal change and reduces this protection. But the lack of testosterone in men is also a risk factor, and women with a greater amount of male sexual hormones are at a higher risk.
On the other hand, the stomach circumference in women has a better diabetes predictive power than in men,"Alexandra Kautzky-Willer, diabetes expert, professor for gender medicine in Austria and study author, said in a press release.
For instance, the protein Fetuin-A formed by the liver as well as Copeptin, and proneurotensin are biomarkers in women but not in men. You can get them over the counter and are specially designed for people suffering from diabetes.
As you do not get any sensation of the hurt, it is possible that there could be redness or pain.
Death of cell and tissue may target any part of the body, however, it has been typically observed in the extremities, such as the toes, fingers and hands. In both, type 1 and type 2 diabetes, the raised level of sugar is capable of causing damage to the blood vessels and reducing blood supply.


Owing to the nerve damage, the transmission of sensation, particularly those of pain to the brain gets impaired.
A notorious bacterial organism, Clostridium perfringes is often linked with gas gangrene; after it attacks the site of injury or sometimes, surgical wound. With a professional advice behind you, you may most probably need to make your next visit to the podiatrist. This means, the footwear you use should be wide enough so that the tips of the toe do have enough space to move in its vicinity. A podiatrist can make such footwear available that are specially designed for the diabetics. In the absence of a continuous supply of nutrient and oxygen rich blood, the cells within the body begin to fail in carrying out their normal function and finally give up. As a result of restricted blood circulation to the extremities, such as the feet, the area becomes deprived of those cells (white blood cells) which aid in fighting off any infection.
Swelling and inflammation resulting from the infection causes the local temperature of the area involved to be slightly elevated, and also leads to pain.
A Tzanck smear obtained from the base of an intact blister was positive for multinucleated giant cells. Suppressive antiviral therapy would be offered if the patient experiences frequent or long-lasting recurrences.



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Comments

  1. 707

    Eat the identical few meals fewer grams of carbs per day, whereas.

    30.04.2015

  2. Patriot

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    30.04.2015

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    Frozen dessert is made by these substances: five the entire carbohydrate content.

    30.04.2015

  4. shakira

    Due to the decreased production of insulin.

    30.04.2015

  5. KOMBATin_dostu

    On the in the future I tried it form of amylin, a hormone that is related to insulin one.

    30.04.2015