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Diabetic nephropathy is kidney disease that develops after years of development of diabetes that is insulin dependent or not. Diabetic nephropathy involves removal of albumin in the urine due to kidney damage, decreased glomerular filtration rate (after an initial increase in type 1 diabetes) and hypertension.
Renal failure due to diabetes when, as is the case of one third of type 2 diabetics with ESRD, also reflects an alteration of the small vessels called microangiopathy. Mortality of diabetics with ESRD appears to be particularly increased for women or in cases of type 1 diabetes. It is estimated that more than 400,000 diabetics have chronic kidney disease stage 3 and 4 (very severe renal impairment and severe) in France.
Diabetic nephropathy is due to an alteration of normal renal glomeruli that filter blood to produce urine.
Stage 1 begins with the onset of diabetes, is characterized by an increased glomerular filtration rate and renal hypertrophy.
The evolution is more complicated and, in one third of patients, the deterioration of renal function may occur without the appearance of microalbuminuria. After three, the same glomerular disease can be different from the typical glomerulopathy of diabetes. No symptoms are detectable in the early stages of diabetic nephropathy that is why annual reviews are required.
All diabetic patients should be regularly tested with a dipstick test (simple test is to dip a dipstick in freshly voided urine and read the result with color calibrations) to detect the onset of microalbuminuria : every year from the 5 th year of diabetes in type 1 diabetes, and every year since its discovery in type 2 diabetes. It takes at least two positive tests over a period of 3 to 6 months to confirm the diagnosis. It must also have eliminated other causes, especially urinary tract infection or other renal disease. Proteinuria is confirmed by an assay of a sample of urine or urine collection issued for 24 hours. In conclusion also the dipstick to make each year to detect the onset of microalbuminuria, kidney function is assessed annually by assaying plasma creatinine and research and quantification of proteinuria (flow glomerular filtration medium is estimated according to MDRD formula). However, we can make the test more frequently when proteinuria is important.
The severity is directly related to the stage where the diagnosis is made and treatment options. In type 2 diabetes, the onset of microalbuminuria is an ominous sign since the survival at ten years is estimated at 25% (against 60% in its absence). Protection of the kidneys requires above all a satisfactory control of diabetes, hypertension and hypercholesterolemia when it exists. Need a good diabetes control (blood sugar) due to diabetic treatment for the chronic imbalance (blood sugar in the blood is too high) promotes the development and progression of nephropathy. We must also fight against cardiovascular risk factors such as obesity or physical inactivity.


At the stage of ESRD, the treatment of it is based, as for other causes of renal failure on peritoneal dialysis, hemodialysis and transplantation (kidney alone, pancreas-kidney or islet).
The proportion of diabetics among patients starting hemodialysis, peritoneal dialysis or transplant patients is higher for women (25% in 2005) than men (21% in 2005).Moreover, women with diabetes on dialysis have a worse prognosis than men.
Maintain a regular exercise even moderate achieves a better balance in the rate of blood sugar (glucose) and thus prevent the development of diabetic nephropathy.
The strict carbohydrate balance is essential: first by a low-carbohydrate diet (carbohydrate) and then by antidiabetic drugs (oral or injectable) or insulin.
Yes, if it is neglected it leads to dialysis or a kidney transplant. Preventive treatment is essential. In type 1 diabetes, the frequency increases every year to reach a maximum of 20 to 40% after 20 to 25 years of diabetes. In type 2 diabetes, the frequency is slightly lower, between 10 to 30% after 25 years of evolution. In type 1 diabetes, men are more affected than women. The risk increases if the diabetes occurs between the ages of 10 and 20 years. No, the diabetes control is essential and requires a diet low in simple sugars (sodas, pastries, …) and providing daily carbohydrates (starches, legumes).
Yes, losing a few pounds and weight stabilization may allow better control of diabetes and thus protection of the kidneys. Yes, the treatment of diabetes, high blood pressure contribute to inhibiting the progression of diabetic nephropathy but the best treatment is prevention.
Medical specialty that studies the function, diseases and ways to treat the endocrine glands (those that produce hormones) and metabolism (all body functions essential to life as, for example, production and glucose utilization ). The hormonal imbalance are varied: poor growth, weight loss or, conversely, weight gain, obesity, diabetes, abnormal lipid regulation, infertility, problems of rules. Copyright © 2012 Rayur, All trademarks are the property of the respective trademark owners. Medically termed as Herpes labialis, Cold Sore is referred to as the infection of the lips, gums or mouth caused by the herpes simplex virus type 1, forming small yet painful blisters (also known as fever blisters). Advanced Medical Inspection EquipmentsThe accurate diagnosis can be a powerful guarantee for the kidney disease treatment While the accurate dialysis needs the support from the advanced medical inspection equipments which achieve world-class level. Patients BlogIt is such a place where you can share your experience, see the international news about kidney disease and find the answers to the questions bothering. Since 1986, Shijiazhuang Kidney Disease Hospital of China has been dedicated to providing the highest quality care to Kidney Disease patients all over the world.Learn more about Chinese hospitals.


Chronic Renal Failure can cause extra fluid to build up in the lungs, leading to shortness of breath. Dialysis can help remove wastes and excessive water out of body to a certain degree, which relieves pulmonary edema and then shortness of breath will be naturally treated. But it is a fact that no one patient with Chronic Renal Failure wants to experience dialysis treatment. Suspicion of another kidney disease?) But, in most cases are diagnosed without biopsy. Especially in type 1 diabetes or association of microalbuminuria and retinopathy is suggestive of diabetic nephropathy. It can be very dangerous if the timely treatment can not be adopted when condition becomes severe. Anemia, a common complication of Chronic Renal Failure which starves your body of oxygen, can also cause you to feel winded or short of breath. Initially, it may not cause any symptoms or mouth ulcers, while the virus remains inactive within the face’s nerve tissue.
As a patient with Chronic Renal Failure, if you are suffering from shortness of breath, the following information is expected to be useful.
However, some people experience the reactivation of virus, releasing recurrent cold sores in the same area, but are not severe.
The shortness of breath in heart failure is caused by the decreased ability of the heart to fill and empty, producing elevated pressures in the blood vessels around the lung. Because it aims at repairing kidney damage and recovering kidney function, it begins to arouse more and more attention around the world. With the recovery of renal function, a series of symptoms will be naturally relieved, also dialysis and kidney transplant can be effectively avoided. If you are interested in this natural treatment and want to know more about it, leave a message below or you can directly consult online doctor by typing Hello on the service box, it is free.



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