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Consequently, it is a true opportunistic pathogen, as it requires a major breach in the host’s innate defenses. Nutrient agar plate (tryptic soy agar, TSA) with Staphylococcus epidermidis and Staphylococcus epidermidis. Those most susceptible to infection are intravenous drug users, newborns, elderly, and those using catheters or other artificial appliances. It is a catalase-positive, coagulase-negative, facultative anaerobe that can grow by aerobic respiration or by fermentation. Healthy individuals can posses up to 24 strains of the species, some of which can survive on a dry surface for long periods. 1998) Disease Infections are associated with intravascular devices (prosthetic heart valves, shunts, etc.) but also commonly occur in prosthetic joints, catheters, and large wounds.

Catheter infections along with catheter-induced UTIs lead to serious inflammation and pus secretion. Septicemia is especially prevalent resulting from neonatal infections, particularly in very low birth weights. Endocarditis is an infection of the heart valves and parts of the inside lining of the heart muscle.
This film is adhesive to hydrophobic biopolymers of prosthetics, creating diseases such as endocarditis.
The gene icaADBC has been found to code for both the polysaccharide capsule and the polysaccharide intracellular adhesin used in biofilm formation.
1998) Another potential virulence factor that’s currently being researched is the fibrinogen binding of S.

The complete gene, termed fbe, was found to consist of an open reading frame of 3,276 nucleotides encoding a protein, called Fbe, with a deduced molecular mass of ~119 kDa. 1998) Implant biomaterials are instantly covered by circulating plasma components, like Fibrinogen, promoting adhesion of host cells. One complication that may arise is when contaminating bacteria adhere to the same components on the biomaterial surfaces, leading to infection. Results found indicated that of a total 184 infections, 56 were directly attributed to S.

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