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Coagulase-negative staphylococci (CNS) are an essential part of the commensal flora of the human and other warm-blooded animals skin and mucous membranes.
Bring the tribes, the foreign body-associated infections usually come from the endogenous flora of patients. The current Miq Directive (quality standard for microbiological and infectious diseases diagnostics of the German Society for Hygiene and Microbiology) for blood culture diagnostics determines that it is questionable in the detection of bacteria of the normal skin flora such as S. Foreign body-associated infections often have a chronic course, because they're in the depths of biofilms, bacterial cells present largely protected from the effects of antibiotics and the immune system.


Bacteria forms white colonies 1-2 millimeter in diameter after 24 hour incubation and it grows best in aerobic conditions. Rifampicin should be used because of the rapid development of resistance only in combination with another MRSE-effective antibiotic. They do people are classic opportunists, only possess a low pathogenic potential for immune-competent individuals. This process is in the presence of matrix proteins (eg fibrinogen, fibronectin), which cover the foreign body in the macro-organism, become stronger.


With regard to the detection of oxacillin resistance testing (methicillin) is resistant strains (MRSE) is important, since these strains can not be treated with beta-lactam antibiotics. Biofilms are sources of infection from which bacteria are flushed into the bloodstream and cause sepsis-like illness images.



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