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Promising research from a University of Newcastle team suggests that Type 2 diabetes can be cured in just eight weeks by diet alone. The short term, very-low calorie diet was initially designed to mimic the rapid reduction of calorie intake that results from bariatric surgery—which is known to be effective in reversing diabetes very quickly. In 2011, the Newcastle researchers conducted their first study using the diet, and the results were impressive.
Pre-breakfast blood-sugar (fasting plasma glucose) levels returned to normal and stayed normal for the remainder of the study. Glucose production from the liver decreased, while the liver’s insulin sensitivity increased significantly. Pancreatic functioning was restored to normal with regards to glucose sensitivity and insulin secretion.
Average weight loss was 33 lbs (15.3 kg), which represented about 15% of initial bodyweight.
Nowadays, fasting protocols—usually involving calorie reduction, not total calorie elimination—have become far more common. In a recent article written for The Daily Mail, Mosely discussed the diabetes reversing diet and even provided a weekly menu.
The researchers’ main emphasis is on losing 15% of total bodyweight, because this level of weight loss appears to promote sufficient fat loss in the liver and pancreas, catalyzing their return to normal function, which then leads to the reversal of Type 2 diabetes. While the researchers conducted their experiments with mostly liquid meal replacements, Mosley uses a real-food Mediterranean approach. To tilt Mosley’s diet even more toward Plant Paleo, simply replace most or all of the oil with additional whole foods.
Regardless, I give Mosley’s real-food, 8-week diet plan a thumbs up if the rest of it looks as good as what we see above. It’s worth mentioning that the Newcastle protocol is effective for diabetics who carry a normal amount of weight, not just the overweight or obese. Diabetes kills over 70,000 people a year in the United States and contributes to 200,000 more deaths. As I promised earlier this year on my podcast, I’ll continue to mention the Newcastle research when diabetes comes up on the show, at least until the Newcastle Research becomes common knowledge. Again, please share this article with anyone you know who might benefit from this information or with your social media circles.
I suspect they do it VLC is to dimish the hefty BG spikes the first couple of weeks or so, and perhaps ethical considerations play a role. I still have more liver and pancrease fat to clear out, only day 11 of my 1,200 – 1,500 mostly potato diet.
The researchers don’t even seem too hung up on losing the weight rapidly, but suggest that it might work better for some people who have a hard time with losing weight slowly. Mosley’s diet (pictured in the article) would be ideal for people who would like to follow a Mediterranean diet for long-term maintenance. How about lean people (<20% bodyfat as per DEXA scan), who have poor starch tolerance but no insulin resistance?
Also, have you seen a study correlating “android fat %” (visceral fat) as per a DEXA scan, with pancreatic and liver fat?
Even when study subjects are forced to eat so much that they didn’t lose any weight, a plant-based diet can still reverse type 2 diabetes in a matter of weeks. All patients in the Ma-Pi 2 diet group had their glucose levels reduced to the point of being comparable to subjects without type 2 diabetes (target values), following 21-day intervention in a supervised environment. If I personally had diabetes, I would attempt to reverse it using the Newcastle 800-calorie protocol and Plant Paleo guidelines for my food choices—since I already know this diet works for me and I enjoy sticking with it.
If that didn’t work, I’d continue to try other modalities known to reverse the disease, before deciding to live with it the best I could and moving on to some diabetes management protocol. It seems to me T2D treatment should start with an aggressive attempt at reversal as soon as it is diagnosed (or earlier). As for the success with the vegan approaches listed in Greger’s video and the Ma-Pi 2 diet, I have little doubt that they do work. In my opinion, Greger also implies that the studies he cites in his video suggest a Vegan diet is the best long-term, longevity diet, too.
When we try to create a perfect bite of food in every spoonful or to put together a perfect plate of food every time we eat, I think then we run into problems. Your donations are gratefully accepted, and I'll be sure to thank you (by first name & location - if provided) on the next episode of Latest in Paleo! Findings from a recent study showed that reversing brain inflammation with a natural flavonoid called Butein in mice can improve symptoms of obesity and type 2 diabetes.
Results from this study strongly suggest that a diet high in fats is responsible for the activation of body inflammations in the brain, leading to impairments in the signaling leptin and insulin pathway, ultimately causing obesity and obesity and type II diabetes. The research team recommends that further investigations on Butein be conducted before sound conclusions can be drawn on it being a potential treatment target for patients with obesity and type 2 diabetes. Daniela holds a PhD in Clinical Psychology from The University of Edinburgh, United Kingdom, a MSc in Health Psychology and a BSc in Clinical Psychology.

Boehringer Ingelheim’s and Eli Lilly and Company’s joint product, Synjardy (empagliflozin and metformin hydrochloride,) has received U.S. It is generally assumed, in health-related research, that males and females of a given species respond to a specific drug in much the same way. Disclaimer:Diabetes News Journal is strictly a news and information website about the disease. Fortunately there is one doctor who can explain this complicated subject in a remarkably simple to understand and even entertaining way: the Canadian nephrologist Dr. This presentation - The 2 Big Lies of Type 2 Diabetes - was recorded earlier this year at the LCHF Convention in South Africa. Sign up for the entire online convention - 30 presentations by the top LCHF experts in the world - for a one-time fee of $69 dollars or $49 dollars using this link.
Don't have time to see this great presentation or not inclined to use any of the two options requiring sign-up?
Finally there's a drug that can help people with type 2 diabetes live longer and healthier lives. Looking for early signs of type 2 diabetes usually involves measuring blood glucose - either fasting or after drinking a glucose load. Daily food intake was limited to three liquid meal replacements (totaling 600 calories) and three servings of non-starchy vegetables (totaling 200 calories). At the time, the researchers were hesitant to recommend their diet, noting the small sample size and other weaknesses of the study. Mosley has now introduced The 8-Week Blood Sugar Diet, based on the Newcastle University research, his own experience with reversing diabetes, and his expertise with calorie restriction.
The menu is very low calorie, Mediterranean, and ketogenic all at the same time—yes, at just 800 calories per day this will put dieters into ketosis. Presumably, other diets that stick to the 800-calorie per day rule will deliver similar results.
In fact, this study suggests that Asian Americans with a BMI greater than 23 should be tested for diabetes, whereas the cut of is typically 25. Twenty-nine million people live with diabetes and 8 million of them don’t even know they have it. Of course, there is a possibility that results from further research will regress toward the mean, but for now there are numerous positive anecdotes, the research is promising, and the therapy seems especially plausible because it lines up with the diabetes reversal we already see in post-op bariatric surgery patients.
Even those who try the program but don’t succeed in reversing their diabetes will likely experience other major improvements. Then, you might want to take a look at The Plant Paleo Diet to see how I eat to maintain my body transformation and health. That liver and pancrease fat is going to clear out on alomst any 800 kcal diet, so why not mimic more like you might be eating whole foods going forward, like with lots of potatoes as I’ll be doing? Ate another half pound of potatoes (roasted fingerling, tossed with fresh spinach & a bit of OO) for dinner, along with a chicken breast.
BG spikes for the fist few weeks aren’t going to cause long-term irrevocable damage, can be covered by insulin anyway, but perhaps more importantly, going much higher whole food cellular carb would allow both researchers and test subjects actually observe the curing process with much higher and more valuable resolution over time. Some people find it easier to follow one particular diet, and this has to be recognised as being practically important.
Losing 15% of bodyweight will result in some muscle loss for most people, but if that’s outweighed by the desire to reverse diabetes, one could still give the Newcastle protocol a shot. Then, I would transition to a weight-maintaining calorie level, still on Plant Paleo, for long-term success. Those unwilling or unable to follow the protocols should at least be given the opportunity to try them.
They are nutrient rich, high in fiber containing whole foods, and are probably a heck of a lot better than the diets the study subjects transitioned from. For example, if you start with a whole-food, plant-based diet, but weekly you add about 6-8 oz of meat, 1 or 2 eggs, and you use animal stocks in cooking, that’s not going to alter the fat load significantly. Alex Tups from the Centre for Neuroendocrinology and Department of Physiology at the University of New Zealand. The researchers observed that administering butein in the mice’s brains attenuated high fat diet-induced body weight gain, body fat mass accumulation, increased energy expenditure and reduced arcuate SOCS-3 expression, indicative of enhanced leptin signaling. Her work has been focused on vulnerability to psychopathology and early identification and intervention in psychosis. Food and Drug Administration (FDA) approved Adlyxin (lixisenatide) as a new treatment for type 2 diabetes this week. Powered by OwnLocal – helping local media with innovative print to web and directory software.
Why do we consider it normal that everyone is getting sicker while on conventional treatment?
And still conventional medicine treat it as the opposite - as a chronic and progressive disease.

Their protocol is known to be effective in subjects who have had diabetes for up to 10 years, and they are optimistic about it working for some who have had the disease even longer. Reasonably, they wanted to see further randomized controlled trials and more long-term follow-up, before recommending the diet.
It will also result in consuming a greater volume of food, which will make those 800 calories stretch much further. This is an example of an entire population whose tolerance is generally shifted down, but there can still be great diversity within ethnicities, as well. Upwards of 80 million Americans are pre-diabetic and steadily marching toward the full blown disease.
I’ll continue to update this article with further resources as they become available. It's an omnivorous diet that is heavy on plant foods, based on scientific evidence and evolutionary clues (Part 1 and Part 2). Even many life-saving drugs have harmful side-effects for many, but there’s a context and net benefit calculation involved. The critical points are to lose at least 15% of bodyweight, fat in the liver, and about a gram of fat in the pancreas—and then hopefully one finds himself in the group of people whose glucose and insulin sensitivity return to normal. There are known, documented paths that have led to reversal, yet they haven’t been promoted as strongly as the pure management protocols. Greger didn’t mention Nathan Pritikin’s diet, for instance, which also had a great track record for reversing diabetes, while it included meat and non-fat dairy. Also, on the days when you eat meat or an egg, you can decrease the consumption of nuts, seeds, while increasing leafy greens.
The mice examined were obese either due to a leptin deficiency or due to a diet high in fat.
This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
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Pritikin’s diet, like the others, was also around 70-80% carb, 10-15% protein, and 10-15% fat.
Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
Fees are used to fund Diet Doctor and keep the site 100% free of ads and corporate interests. They share in common that they are all nutrient-rich, high-fiber, whole-food diets that minimize or eliminate added sugars and oils—this is likely more important than the vegan angle Greger focuses on. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. Those feasts can be balanced with a day of calorie-restriction or fasting every month, too. The EmailFirst off – your updated site is absolutely awesome – very professional, yet extremely user friendly! You added my story a while back about ending my 26 year insulin, metformin, and a ton of other medication dependence.The heaviest I was ever in my life was 264 lbs (120 kg), way back in 1992. I studied it for several months then began following this way of living seriously in April of 2015. I was dedicated and determined and followed the plan of very strict low carb closely, until I would blow up and do something foolish, and begin again. This way of eating is simple, satiating and easy to manage and completely eliminated any need for insulin, metformin and all things diabetic, BUT, and this is a big but, one toe over the line into the carb world and my sugars soar! More impressive are completely reset sugars, blood pressure, even my Crohn’s and esophageal diseases are improved.
I think the fasting, many 3-day short term fasts and two 21-day total fasts really helped me. I find fasting very easy to do, once you get past the historic teaching of ‘need for food and to eat regularly’ you are, for the most part, fighting only your own mind and incorrect teaching about what our bodies can do! I am an older, wiser, retired RN who lives to read and learn – how could I be soooo stupid ? Once I understood what my body could do to save me, thanks to Jason Fung’s teaching, and followed the lifestyle Andreas Eenfeldt is preaching.

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