Recent drugs for diabetes mellitus,best medication for type 2 60v,mechanisms of insulin resistance in type 2 diabetes mellitus,diabetes mellitus power point en espa?ol - Downloads 2016


Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. This ppt covers recently FDA approved treatment of DM and other drugs that are in clinical pipelines or still under consideration. Recent breakthroughs in type 2 diabetes treatments promise new treatment options for type 1 diabetics.
Less than 20 years ago, the only thing type 1 and type 2 diabetes seemed to have in common was a shared name; they were related conditions but only as distant cousins, and once removed, at that.
Doctors and researchers discovered the last decade that, for a variety of reasons, many type 2 diabetics could benefit from taking insulin. There are numerous causes for this, according to Andrea Penney, RN, CDE, with the Joslin Diabetes Center.
That change in thinking about the ways type 2 diabetes evolves indirectly opened the door to considering new ways of thinking about how type 1 diabetes behaves. There is only one treatment besides 54 varieties of insulin approved by the Federal Drug Administration for use by type 1 diabetics, according to the University of Maryland Medical Center, and that drug is pramlintide acetate, which is marketed under the name Symlin. Pramlintide is a small peptide hormone produced in the pancreas and, in people without diabetes, is released alongside insulin after meals or food ingestion, to help reduce high blood sugar. According to the FDA, which approved Symlin for use in treating type 1 diabetes in 2005, “Symlim is an injectable medicine for adults with type 2 and type 1 diabetes to control blood sugar. Symlin’s manufacturer, Amylin Pharmaceuticals, Inc., says that Symlin works to reduce blood sugar by generating a feeling of fullness after meals, slowing the rate that the stomach empties after meals, and reduces the release of glucagon from the liver after meals. Some doctors are also prescribing metformin, which is the most prescribed oral type 2 diabetes treatment in the United States, off label as an adjunct to insulin for type 1 diabetics.
Other drugs used to treat type 2 diabetics are being studied to see if they should be submitted to the FDA for approval to treat type 1 diabetics. GLP-1 is a naturally occurring hormone released in the intestine that stimulates the release of insulin from pancreatic beta cells when carbohydrates are absorbed in the intestine. Some limited research suggests that GLP-1 treatments might be effective in helping type 1 diabetics better control their blood sugar. A full-scale clinical trial of Victoza on type 1 diabetics is potentially in the works from the maker of Victoza.
Then, this January Novo Nordisk started recruiting more than 1,400 subjects for a 52-week trial on the effects of Victoza on type 1 diabetics. Until that trial is completed and the FDA acts, however, Byetta, Victoza, and Bydureon are explicitly not approved for use by type 1 diabetics, according to the product warnings on each drug.


If any type 1 diabetic wishes to try the drugs off label (which is the medical jargon for when patients receive a prescription to use a drug for a purpose for which it has not been FDA approved) researchers and doctors suggest consulting with a qualified endocrinologist experienced both in prescribing GLP-1 drugs and treating type 1 diabetics. Anyway, if this sounds interesting to anyone, they’re currently enrolling people in a year-long study to see if regular treatment with Bydureon (the once-a-week version) is helpful to people with Type 1. The Diabetes Media Foundation is a 501(c)(3) tax-exempt nonprofit media organization devoted to informing, educating, and generating community around living a healthy life with diabetes. There is no denying that there is a distinct correlation between people with diabetes and people who suffer from obesity. Although factors like age, race, and family history contribute to diabetes and obesity, the conveniences of modern life are prevailing as a cause of these diseases. According to the Center for Disease Control, about 80 to 90 percent of the people diagnosed with type 2 diabetes are also diagnosed as obese.
Insulin is the hormone produced by the pancreas that enables your body to absorb the glucose in your bloodstream. IBD’s most stringent and powerful screen, Sector Leaders highlight the best stocks in IBD’s 33 sectors. Sector Leaders Paycom, Atlassian and IBP all have something different to prove in their earnings results this week.
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NorthCoast Asset Management kept its ETF retirement portfolios stocked with domestic ETFs amid the market volatility. Navigating this world of new, and apparently improved drugs, however, is anything but simple or straightforward. The paradigm at the time was that type 1 and type 2 diabetes required different treatments because they were, in fact, very different conditions. The recently realized realities regarding the ways each condition evolves and behaves has led to new ways of treating each type of diabetes and a sharing of therapies between the two. That shift led to considering whether that door swung both ways and if type 1 diabetics might benefit from treatments designed to treat type 2 diabetes.
Symlin is recommended for type 1 diabetics who have not achieved good blood sugar control, which is decided on a case-by-cases basis by a person’s physician.


These drugs, once-daily injectable Victoza, Byetta, and once-weekly injectable Bydureon, are all GLP-1 agonists.
Additionally, GLP-1 (which stands for “glucagon like peptide”) is also present in the brain, where it acts as an appetite suppressant and produces one of the same effects of taking Symlin.
I want to add to Kelly’s experience by saying I was in a tiny, preliminary trial using Byetta, and was astounded by the result. Diabetics give themselves injections of insulin in order to be able to absorb the glucose from their bloodstream because they either do not produce any insulin or they produce very little.
Try 4 weeks of IBD Digital Premium and get instant access to exclusive stock lists, proprietary ratings and actionable stock analysis. Includes MarketSmith platform plus Pattern Recognition and exclusive Growth 250 stock idea list. All Sector Leaders show outstanding earnings and sales growth in recent quarters and are strong across many other fundamental and price-performance metrics. In type 1 diabetes the pancreas stops making insulin so type 1 diabetics injected insulin to replace what the body was no longer producing. Type 2 diabetes, however, was a condition in which a person’s pancreas was producing insulin, but their body was not metabolizing and using the hormone efficiently. People can also become insulin resistant due to weight gain or chronic emotional or physical stress.
Since excess glucose is stored as fat, you may gain weight if you do not follow a careful diet. Type 2 diabetics took oral medications to help improve their ability to metabolize the insulin their bodies were producing. What’s more, normally, Byetta is thought to work by boosting insulin production (in people with Type 2). But when they analyzed my blood, they found that I was producing LESS insulin on the Byetta day than I was during the regular glucose tolerance tests. We are really excited by these results so far and are anxious to see if her A1C has gone down!



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