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Beta cell function declines in response to multiple factors in type 2 diabetes, and insulin therapy has been shown to counteract several of these. Studies[1] have shown the effectiveness of short-term intensive insulin therapy (IIT) early in the presentation of type 2 diabetes. Since then I’ve treated dozens of patients this way and I am shocked by the successful results. A few studies (see footnote 1) conducted on patients close to the time of diabetes diagnosis show that when insulin is given this way for a few weeks, the patients can revert to a state of no-diabetes for one to two years.  It is believed to be due to the fact that the beta cells improve their function when they are no longer smothered in sugar. Since these patients have had diabetes for many years, what are your expectations after the intensive insulin therapy? Some beta cell deterioration is reversible and some is not.  It seems to depend on how long the patient was exposed to hyperglycemia and the degree of hyperglycemia.
Those who are recently diagnosed are able to come off medications for one to two years and remain in good control. Certainly not on all patients, but in those who I don’t manage to take off the insulin entirely, they often remain only on a low dose of long acting insulin. It seems like you have to bring the patients’ blood sugar levels quite close to normal for this to work. In my clinic I have always seen glucose levels decrease relatively slowly but surely, with no hypoglycemic events because the insulin is given in a physiological way, and the treatment includes very frequent contact with the doctor, nurse, and dietician.
A recent publication from the ACCORD trial actually showed that the intensive arm  (which reached HbA1c levels below 6.5% ) had great glucose control more than one year after therapy is relaxed[5], which is similar to my findings.
This whole process seems like a lot of work for you and the patients, but the results are so impressive.  I assume it’s all worth it.
The Diabetes Media Foundation is a 501(c)(3) tax-exempt nonprofit media organization devoted to informing, educating, and generating community around living a healthy life with diabetes. Gestational diabetes, which can be a temporary condition during pregnancy and get corrected after childbirth, needs due treatment so that it does not prove harmful for the unborn baby or her mother.
Usually, women having gestational diabetes can control their blood sugar and have healthy babies. You should aim at bringing your blood glucose levels, usually measured in terms of milli moles of glucose in one liter of blood, as close to the target as possible.
Women may need medication to control their gestational diabetes and protect their babies from potential damage. Gestational diabetes can also be treated through drugs called glyburide and metformin which are used for treating type 2 diabetes. You can enjoy healthy living even without indulging into expensive and extensive exercising or gymming. During pregnancy, you can be advised to monitor fetal movements through kick counts, ultrasounds, baby’s heart beat and non stress test. You may need more than the usual checkups when having gestational diabetes to ensure the health of your baby including your own.


For example, treatment with insulin can reduce glucotoxicity – the toxic effects of excess sugar in the blood, lipotoxicity (due to chronically elevated free fatty acids), inflammation, and resistance to incretins. High glucose levels are toxic to cells (glucotoxicity), which means that the cells are stunned and cannot secrete insulin appropriately. Those who have had diabetes for ten years (which is the average I see in my clinic) are able to significantly improve their insulin secretion, but must continue to take simpler medications, that don’t require frequent checking of blood sugar levels because they don’t lead to hypoglycemia. Eating a low carb diet and doing some kind of physical activity, of course, significantly improves the chances of coming off insulin, even if the patient has been a diabetic 20 years. In these patients who on average have had diabetes for 10 years, are you concerned about the data from studies like the ACCORD trial[3] which showed that bringing glucose to near-normal levels in patients with long history of diabetes increased cardiovascular risk.
The interesting part is that many patients actually enjoy the process because insulin becomes a tool that empowers them and gives them back control over their life (even for those on multiple shots a day for years). By excessive amount of blood glucose or blood sugar This is due to a lack of the hormone insulin into the body , or because the insulin is present in the body, is not absorbed by the body If you think a diabetes medication, you probably think of insulin. Furthermore, there is a tendency for women having gestational diabetes to later have type 2 diabetes. The risk for developing type 2 diabetes can also be controlled (reduced) by adopting some preventive measures when you have suffered from gestational diabetes. By adhering to the required concentration of glucose in blood, you can control gestational diabetes and its potential unfavorable effects.
Women having gestational diabetes should adjust their diet and lifestyle to have effective control over the condition. A simple exercising as walking several times a week can go considerably in controlling blood sugar. You may adhere to the low-impact activities, like walking or swimming, or try special exercise classes for pregnant women. Healthy choices in living can show results now and later. Glandt is applying this same concept to treat diabetes years after the original diagnosis.  In her private practice she has brought over 80 patients with complicated diabetes to a place where their diabetes is much easier to manage, and they have near normal A1c’s. I achieve this with the help of a glucometer called Insulinx, which has a built in sliding scale and recommends to the patient how much insulin to take according to what I program in it, and the dose is something that I change on a weekly basis.
But as patients gain control over their lives and they feel great because they are no longer tired due to the chronic hyperglycemia, I sometimes have to convince them that it’s time to stop. Treatment becomes significant owing to the complications, including the short and long term outcomes, of diabetes.
When you take insulin, you may be required to check blood glucose before going to bed at night. While you should avoid dieting during pregnancy, you may have to keep a check that the recommended calories intake is not exceeded.
You can start feeling more energetic and refreshing after knowing how your body benefits from eating correctly and exercising regularly.
Your doctor can assist you in determining the frequency and method of testing blood glucose levels.


But before taking insulin shots, you may have to focus on controlling blood sugar through diet and lifestyle changes. Healthy choices can help prevent gestational diabetes in later pregnancies and type 2 diabetes as well. Weight gain is an important aspect of pregnancy and pregnant women can gain anywhere from about 11kg to 16 kg. During gestational diabetes, you may have to test both types of blood glucose levels throughout pregnancy.
You may be eating a healthy diet but having gestational diabetes can demand specific quantity and quality of foods in diet. But overweight or obese pregnant women may have to eat less and gain less weight owing to their increased risk for high blood pressure and preeclampsia. A healthy diet is important for the control of blood glucose, a healthy body weight, and reduces the risk of other health conditions, including heart disease.
In addition helps in losing weight and improving overall health, exercise has a direct effect on blood sugar. The ADA recommends that people get with type 2 diabetes at least 150 minutes of exercise per week or 30 minutes per day, five days a week. People with diabetes who need to lose weight should try 15 to 20 percent of their body weight lose, advises Pantalone.Metformin. Metformin works by decreasing hepatic production of glucose (sugar) and increasing the body’s sensitivity to insulin.
If an A1C of less than 7 percent is not reached by then, another diabetes medications may be added.Type 2 diabetes treatment metformin afterIf metformin and lifestyle changes are not enough to control blood sugar, your doctor will adjust your treatment plan.
The reason why it is not as frontline treatment that they sometimes cause blood sugar is too low (hypoglycemia) dip and can cause weight gain.Meglitinide. This diabetes medications are short acting, so they must be taken three times a day before meals. These diabetes medications slow the rise in blood sugar by stopping the breakdown of starch in foods such as bread and potatoes as they digested. Their use is limited because they are not as effective as other types of diabetes and drug side effects often cause flatulence and diarrhea.Incretin agents. DPP-4 inhibitors help your body to use their own compound that lowers blood sugar.Non-insulin injectable drugs. Exenatide is an injectable diabetes drug that increases insulin secretion, but it can cause nausea. Liraglutide, which is injected once daily, stimulates insulin production and can help with weight loss.




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