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Disorders of the pituitary may arise when there is overproduction or underproduction of a specific hormone. Pathophysiology and EtiologyHyperpituitarism is the hyper function of the anterior pituitary gland leading to oversecretion of one of more of anterior pituitary hormones . AchondroplasiaThe disorder causes a type of dwarfism that is recognized by its characteristic normal to large-sized head, shortened arms and legs (especially the upper arm and thigh), a normal-sized trunk, and waddling gait.
Diagnostic FindingsFluid deprivation test (differentiates neurogenic from nephrogenic): withhold fluid for 5-6 hours.
Endo 1.07 The pituitary gland Anatomy and histology of the pituitary gland Growth hormone and its control Actions of growth hormone Excess and deficiency. Small protein expressed from anterior lobe of pituitary produced by Somatotroph cells of the anterior pituitary Growth hormone (hGH) is a peptide hormone.
Introduction This tutorial is designed to aid your learning of the endocrine system and also as a useful revision tool.
Adult Medical-Surgical Nursing Endocrine Module: Disorders of the Posterior Pituitary Gland. Pharmacology of the Endocrine System Topics Pituitary and hypothalamic hormones Pituitary and hypothalamic hormones Thyroid and antithyroid Drugs Thyroid.


1 Endocrine Diseases Pituitary Gland University of New England Physician Assistant Program J.B. Homeostasis & Controls Successful compensation –Homeostasis reestablished Failure to compensate –Pathophysiology Illness Death Figure 1-5: Homeostasis. We will discuss the various disorders that occur due to irregularities in pituitary hormone production. There is overproduction of the GH, which is usually due to a benign pituitary adenoma, which causes gigantism or acromegaly characterized by bone over growth.
General Characteristics includes cells, tissues, and organs that secrete hormones directly into the body fluids to help.
After fasting phase, client is given infusion of desmopressin acetate (DDAVP), synthetic analog of vasopressin. The pituitary is located at the base of the brain, in a small depression of the sphenoid bone (sella turcica). Alzaharna (2014) Hypothalamus and Pituitary Gland The hypothalamus and pituitary gland form a unit that exerts. If urine still dilute with low specific gravity, then nephrogenic DI because renal tubules do not respond to ADH.


The condition is usually discovered in the teenage years, and surgical or hormone therapy can be prescribed.
When it occurs in later years, it is usually the result of an injury to the pituitary gland, such as a car accident. Glucose should lower GH levels but in acromegaly GH levels remain elevated.Medical and Surgical TreatmentTreatment of choice is removal of pituitary gland (transsphenoidal hypophysectomy) via nasal technique.
Complications include Increased ICP, bleeding, rhinorrhea, and meningitis.New micro-surgical techniques have been very successful in the treatment of acromegaly. 757).Medication treatment includes oral treatment of bromocriptine mesylate (Parlodel), an oral antiparkinsonism inhibiting release of GH in clients with acromegaly, or cabergoline (Dostinex), or parenteral injectionsocreotide (Sandostatin), lanreotide (Somutaline), or pegvisomant (Somavert).



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