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Tufts OCW material is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. Mensen met diabetes type 1 moeten een paar keer per dag zichzelf insuline inspuiten, of een insulinepomp dragen. When ketones appear in the urine, they signify high levels of blood acids and ill-controlled diabetes.
Urine showing ketones can be an alarming sign for people having diabetes requiring quick medical intervention.  Diabetic ketoacidosis is a severe complication arising out of high levels of blood acids (ketones).
This leads to intoxication of the bloodstream causing diabetic ketoacidosis.  Excessive ketones can lead to poisoning of the body. Diabetic ketoacidosis can also case loss of consciousness, interfering with body’s metabolism. Ketones build up can also lead to abruptly changing fluid levels causing the lungs to fill up. When ketones reach dangerous levels in people suffering from diabetes, diabetic coma or even death can occur.  It is very important to check for ketones through examinations and warning signals. People having diabetes or at risk for diabetes should be aware of the warning signs of diabetic ketoacidosis. During treatment, if blood sugar level is adjusted too quickly it can cause swelling in the brain. Ketoacidosis, which generally develops slowly, can become a fatal condition within a matter of hours.  Attending it immediately is crucial for avoiding life-threatening conditions. Your health care provider may tell you that you need to limit your fluid intake 12 to 14 hours before the test.Your provider will ask you to temporarily stop taking any medicines that may affect the test results. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition.


Surprisingly, some people may recognize their diabetes only due to diabetic ketoacidosis appearing as the first sign. This is owing to insufficient insulin availability and can be more commonly observed in people suffering from type 1 diabetes.
Since there is not sufficient insulin production, the body starts to rely on the alternate source of fuel – fat.
This condition, called adult respiratory distress syndrome, can create serious breathing problems. Diabetic ketoacidosis can be highest among people having type 1 diabetes,  those missing insulin too often and people younger than 19. When there is a sudden (quick) drop in blood sugar level due to insulin administration, there can be incidence of hypoglycemia. The possibility of complications arising out of treating diabetic ketoacidosis are not common now, although they can prove to be concerning when they occur. The clean-catch method is used to prevent germs from the penis or vagina from getting into a urine sample.
Be sure to tell your provider about all the medicines you take, including dextran and sucrose. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions.
Almost 50% of the diabetes-related hospitalizations (type 1 diabetes) can be accounted to this condition.
To collect your urine, the health care provider may give you a special clean-catch kit that contains a cleansing solution and sterile wipes. DO NOT stop taking any medicine before talking to your provider.Also tell your provider if you recently received intravenous dye (contrast medium) for an x-ray.


Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Follow instructions exactly so that the results are accurate.Clean-catch urine sampleA clean catch is a method of collecting a urine sample to be tested. Greater than normal results may indicate conditions such as Addison's disease, congestive heart failure or shock. Women or girls need to wash the area between the lips of the vagina with soapy water and rinse well. As you start to urinate, allow a small amount of urine to fall into the toilet bowl (this clears the urethra of contaminants). Then, in a clean container, catch about 1 to 2 ounces of urine and remove the container from the urine stream.
Open a urine-collection bag (a plastic bag with adhesive paper on one end), and place it on your infant.
For males, the entire penis can be placed in the bag with the adhesive attached to the skin. Martin, MD, MPH, ABIM Board Certified in Internal Medicine and Hospice and Palliative Medicine, Atlanta, GA.



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