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University of Notre Dame researchers have discovered a compound that accelerates diabetic wound healing, which may open the door to new treatment strategies.
The significant role of beta cell 'hubs' in the pancreas has been demonstrated for the first time, suggesting that diabetes may due to the failure of a privileged few cells, rather than the behaviour of all cells.
The prevalence of diabetes in the United states is high, it is currently estimated that 14 percent of the united states suffers from diabetes .
Foot ulcers can be very dangerous and can lead to infections and possible amputations if not treated quickly and properly. There are many treatments available for treating ulcers,   a new treatment that I am performing at the Advanced Foot and ankle Center of San Diego with great success is human amniotic membrane allograft application. The placental membrane contains 2 layers , the chorion which is touching  the maternal side of the placenta and the amnion which is touching the amniotic fluid and fetus. We have been able to cure hundreds of foot ulcers with this new treatment option available . Below are some pictures of before and after healed diabetic foot ulcers that were treated with human amniotic membrane allograft. Diabetic nerve damage or diabetic neuropathy, as it is more commonly called, is a neuropathic disorder associated with damage of nerves because of high glucose levels in the blood.
Diabetic neuropathy is a symptomatic problem, but in some diabetics with nerve damage, there are no symptoms at all. Diabetic patients often complain of numbness, pain or tingling in their toes, feet, legs, arms, hands, fingers, hips, buttocks, and thighs.
Due to diabetic nerve damage, you may develop troubles in digesting food, which further leads to indigestion, nausea, vomiting, feeling fuller even after eating small amount of food, constipation, diarrhea and troubles while swallowing food. You may also suffer from high heart beat and pain in the chest, which can eventually lead to heart attack. Due to autonomic neuropathy, diabetic patients may suffer dis-functioning of sexual organs.
Diabetic neuropathy can lead to overall weakness in the body, fatigue, and frequent sweating, even when the temperature is cool.
Early detection and treatment is the best way of controlling diabetic nerve disorder and preventing its long-term consequences. Some research suggests that wearing certain types of footwear, such as high heels or tight-fitting shoes, might make a person susceptible to bunions. In fact, 88% of American women wear shoes that are too small, according to a study conducted by the American Orthopaedic Foot and Ankle Society. A foot examination might include an assessment of the anatomy as well as having you perform certain movements.
The conservative treatment is rest, custom-fitted shoes (orthotics) and anti-inflammatory medication such as ibuprofen or aspirin.
In cases where the bunion refuses to respond to conservative therapy, surgery is an option. If you feel you’ve lived long enough with the pain and inconvenience of a bunion, call our clinic 972-274-5708 and let’s discuss your options. This is a medical condition that is also known as immersion foot and was a common illness for soldiers during World War 1.
Two of the early signs that can indicate a person has trench foot are redness and numbness of their foot. You may see open sores and blisters on the foot which could indicate that the disease is at a severe stage. The main cause of developing trench foot is standing in water and exposing their feet to cold, wet conditions for as little as eleven hours or longer.

If you start to see symptoms of trench foot or your feet are cold and wet you should soak them in warm water that ranges in temperature from one hundred two to one hundred ten degrees Fahrenheit for at least five minutes. When you have trench foot try to stay off the foot as much as possible, especially if there are open areas. If you have just the beginning symptoms of trench foot you should check your foot very closely to see if there are any wounds. If you notice any symptoms of trench foot you should see your physician immediately to prevent it from spreading and cause long term damage or even loss of your foot.
If you are experiencing pain you can take over-the-counter pain medications or have your physician give you a prescription for a pain medication. The health information provided on this web site is for educational purposes only and is not to be used as a substitute for medical advice, diagnosis or treatment. One hundred seven patients with diabetes and foot lesions of at least a four-week duration were randomized to 30 daily sessions of 90 minutes of HBOT (breathing oxygen at 244 kPa) or sham (breathing air at 125 kPa) in addition to comprehensive wound care.
4 percent of Diabetics will get a foot ulcer during the year and 25 percent of diabetics will gat a foot ulcer at least once in their life time. These types of symptoms commonly occur in peripheral neuropathy, which is said to affect toes, feet, legs, arms and hands. Due to this, you may feel weakness or loss of sensation in the muscles of your feet or hands.
Due to weakening of nerves, they may face issues in holding up urine for long periods, may leak urine or face issues in telling when their bladder is full. Men may face erectile dysfunction, while women report vaginal dryness and difficulty in achieving orgasm. These ‘bumps’ on your feet, which may make wearing shoes painful, are actually composed of joint tissue that’s growing the wrong way. X-rays might be ordered to enable the doctor to analyze the bone structure in your foot, the integrity of the joints and the alignment of the toes. If the skin is broken or there appears to be an infection, antibiotics might be called for. Doctor may advise a bunionectomy, which is an operation to remove some of the growth that’s causing the problem and re-align the toes. The goals are to relieve pain and correct the deformity so that bunions will not cause future problems.
The reason it was so common during this time period is that the soldiers spend a lot of time standing in cold, wet trenches. The reason that it was so rampant during World War 1 is that they soldiers did not have footwear that was waterproof.
After taking it out of the water make sure that you dry the foot completely, especially between your toes. This is especially true if you have any ulcers or blisters that are infected to make sure that the infection does not spread. Trench foot is treatable but it can be a long, slow, and painful process but it all depends on how serious the condition is. Risks for ulcers include bony prominence’s such as bunions and hammertoes that rub against improper shoes that can lead to ulcers. Human amniotic membrane allograft (HAMA for short) is donated from human placenta once a child is born. There are many growth factors in amniotic tissue such as FGF, EGF, TGF  that help stimulate epithilial cell growth and migration and can grow skin in ulcers and wounds. A combination of the chorion with the amnion contains many growth factors to help ne skin cells grow and heal wounds.

Though diabetics can develop diabetic neuropathy at any time during their life, the risk is said increase as the age or disease progresses.
The most common early signs of diabetic nerve damage include numbness or pain in feet and hands, along with tingling. If Doctor decides that your condition is a bunion, then it’s time to talk about treatment options. Your surgeon may also repair the tendons and ligaments around the big toe, to ensure more support. It is a dangerous medical condition and during the wars of the nineteenth and twentieth centuries it caused millions of injuries and deaths.
You may also notice a blue discoloration to your skin which is an indication of a poor supply to your foot. It can also happen anytime your feet are exposed to water for a long period of time that can include everything from excessive sweating to sea travel. Make sure that if your feet become wet or you are sweating excessively causing your socks to become wet, change your socks and footwear immediately. When possible wear sandals or flip-flops to allow the sweat to evaporate from your skin, especially in hot conditions that could cause your feet to sweat. Remember that in order to prevent this medical condition you need to make sure that your feet are kept dry but if they become wet make sure that you get them dry as soon as possible. There is also present PDGF A and B which help the growth of  collagen , fibroblasts and smooth muscle cells. If yes, then do you have diabetes? If you face any of the above symptoms, then there are fair amount of chances that you are suffering from diabetic nerve damage – a progressive disease that can lead to serious health problems.
Moreover, the risk is said to be higher in patients who fail to keep their blood sugar levels under control. Because gout and arthritis can also cause swelling and foot pain, the doctor will perform an examination to diagnose the problem.
In severe cases, we may remove the joint surface and implant a wire or plate to hold the bone in place while it is healing.
You’ll be fitted with crutches, a cane or a walker to keep the weight off your foot until it heals. It does not have to be wet footwear but can also be wet socks that are caused by excessive sweating.
Do not walk around for a long time before doing this as it can cause trench foot and the problems associated with this medical condition.
Do not just change your footwear and leave on your socks, even if they are just slightly damp.
Since nerve damage occurs over the years, most of the times, initial symptoms are often minor and go unnoticed.
It was first recorded as a widespread syndrome during the Napoleonic wars in the early eighteen hundreds in Europe.
Neuropathy is the loss of sensation in ones feet so if you have a pebble in your shoe you will not feel it and then it can lead to an ulcer which can lead to infection….

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