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Gangrene is a serious condition and potentially a life threatening ailment which arises due to the loss of blood supply causing the body tissue to die.It can affect any area of the body though it starts in the toes, feet, hands and fingers but can also occur inside the body, damaging muscles and organs. Primary cause of gangrene is reduced supply of blood to the affected tissues which end up in cell death.
Some of the symptoms of this condition include redness and swelling in the affected part of the body, loss of sensation or severe pain, sores or blister in the affected areas which tend to bleed or produce foul smelling pus. Blood is the most essential element for health since it transports oxygen and nutrients to the entire body to feed cells, in delivering disease fighting antibodies which protects the body from various infection and when the blood circulation is not circulated effectively in the body, the cells are unable to survive resulting in infection and the tissue may die from gangrene. Conditions affecting the blood stream flow could increase the risk of gangrene like atherosclerosis, peripheral arterial disease, trauma, Raynaud’s phenomenon, a condition wherein the blood vessels supplying the skin tends to get narrowed down, besides diabetes and smoking. Wet gangrene occurs with the complication of an untreated infected wound, resulting in swelling from the infection of the bacteria due to sudden stoppage of circulation of the blood flow. Dry gangrene is the result of reduction of blood flow through the arteries and appears gradually and the process is slow.
Gas gangrene is another type of wet gangrene caused by bacteria known as Clostridia which are a type of infection causing bacteria that grow only in the absence of oxygen and as they grow they produce poisonous toxins and gas. I provide cognitive behavioral therapy to people with diabetes in my psychology practice, and have heard similar shame stories from my patients.  I remember a young woman who described her difficulty managing her blood sugars at work. When we peeled back the layers of her thought process, my patient came upon the memory of a classmate from her childhood exclaiming, “Ew, you have diabetes?”  To this day, despite the kindness of many others who have learned of her diabetes, that is the reaction that continued to influence her behavior.  We had to work hard to balance her thoughts and beliefs about sharing her diabetes with others so that she could reduce that persistent sense of shame. I know shame had been at play in my life well before this playdate.  It was shame that made me reluctant to test my blood sugar in public in my early days, or to inject my insulin at the dinner table with friends or on a date. On some level, I believed something was wrong with me, and that something bigger than my insulin pump needed to be concealed.
In the early years of living with diabetes, I was still a young woman in my twenties, and appearances and the impressions of others were important to me.  I didn’t want my medical equipment to show any more than I wanted my emotions and my grief revealed. Sometimes, however, there is something wrong with the perspective of people without diabetes or another chronic illness. Recently, I learned a lot about shame by reading about Brene Brown’s research in “The Gifts of Imperfection”. Michelle Sorensen is a member of the Ontario College of Psychologists and has a private practice in Clinical Psychology in Ottawa.
I think this issue of shame is one of the most important aspects of learning to live with diabetes. Fortunate to come across this article as I recently shared with someone my shame associated with being Type 1. The Diabetes Media Foundation is a 501(c)(3) tax-exempt nonprofit media organization devoted to informing, educating, and generating community around living a healthy life with diabetes.
This year has seen some exciting new developments from the diabetes industry, particularly for continuous glucose monitoring. Looking ahead to 2015, we’re optimistic about these seven diabetes products potentially hitting the market in the next 12 months. The t:slim G4 will provide a strong competitor to Animas Vibe and Medtronic 530G in the US pump market and raise the stakes for the remaining pump providers (Roche, Asante, Insulet) to deliver on CGM integration.
Dexcom continues their forward momentum with expected first quarter 2015 FDA submission of their G5 technology, said Dexcom President and Chief Operating Officer Kevin Sayer in their second quarter earnings call. According to Sayer, Dexcom G5 will be the same manufacturing process as G4, so this will not be an update of their sensor technology, per se, but the user interface and the transmitter will have a new look with new connectivity capability – namely a Bluetooth-enabled transmitter and a smartphone interface to be released first on the iOS platform.
On the heels of G5 approval, we should expect to see submissions from Asante and Insulet, both of whom announced intentions in 2014 for partnership with Dexcom for G5-integrated products, showcasing prototypes at AADE 2014 (Asante) and expected to showcase at ADA 2015 (Insulet).
Speaking of newcomer Asante Solutions, having launched their newest version of Snap with an updated, customizable look and color LCD screen at the end of 2014, they are setting their sites on making their pump available to more users. Next year, we will see Asante submit to FDA for a pediatric indication for users 10 years and older, as well as for a Novolog indication.
For insulin pumpers in Europe, you may see Medtronic Minimed’s newest offering launched as early as April 2015. Sneak peaks of 640G reveal that the Medtronic design is in for a long-awaited facelift with a color screen, portrait orientation, new buttons, and a whole new user interface. The big product buzz in 2014 had to be the FDA hearing and subsequent approval of Mannkind’s inhalable insulin Afrezza. Those of us watching the rise of CGM as it relates to pump integration and data mobility are watching to see how successfully these device companies can maneuver through regulatory and functional hurdles for mobile software.


But you did NOT mention that apparently the Enlite 2G is a compatible replacement for the current Enlite in any context that sensor is currently used in. Nonetheless, all of this talk heralding new devices is just rhetoric unless you can afford them! Pump companies would like us to believe that technology has improved tremendously, but it really hasn’t. Huge improvement made by OmniPod because they could first in the history make tubeless insulin pump. Other manufacturers like Medtronic and Accu-Check Roche should be able to develop their own tubeless device as well.
And by the way why cannot these big companies develop finally a working CGM device what should work without needles, for example a watch. MoliCare Super Plus briefs offer a fully waterproof backing along with extra leakage protection to handle the demand of very severe incontinence.
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Due to termination of the blood flow, the tissues tend to react to the presence of bacteria which multiply and the disease fighting cells - the white blood cells cannot reach the affected areas resulting in becoming moist and wet and breaking down causing death of the tissues.
Regular check-up are essential and quitting smoking followed by adopting a healthy lifestyle with regular exercises and low fat diet should be maintained to reduce the risk of this ailment. Later, when I had started using the insulin pump, shame continued to influence my behavior. I was a people pleaser and I suppose I knew the unspoken rules of how to win people over when you are dealing with a chronic disease.
They cannot accept vulnerability, and they maybe even seize upon it to make themselves feel bigger. I doubt she knew she had provoked such strong emotion in me but I can’t imagine she thought it was a nice thing to say. I related to much of the article like not testing at work or not giving myself insulin at a meal because of how it made me feel. In February, Dexcom’s G4 Platinum CGM was approved for pediatric indication and then, in November, they released their Software 505 update to the G4 Platinum (non-pediatric) receiver with an advanced algorithm being used in artificial pancreas research around the world. Roche launched Accu-Chek Aviva Expert – the first blood glucose meter to track insulin on board and include a bolus dose calculator (especially useful for MDI patients), and Tidepool, the non-profit champion of open source data headed by Howard Look, announced that Asante, Dexcom, Insulet, Abbott, and Tandem had all come on board to open data partnerships.
We could potentially see two new integrated pumps on the market in early 2016, bringing the total to FIVE! The latter has required them to develop a Novolog-specific disposable pump body because their current design is tailored to the specs of Lilly’s 3mL Humalog pen cartridges and the two insulin cartridges are differently shaped.


Taking their Low Glucose Suspend feature to a new level and using a second generation Enlite sensor, 640G will have predictive LGS capabilities (called SmartGuard) and be able to suspend and resume basal delivery based on predicted hypos, performing as a semi-automatic closed loop. We ruminated on its timeline this time last year, but with approval and announced partnership with Sanofi, they are anticipating a US launch in early 2015.
According to the results from late-stage trials in people with type 2 diabetes, Toujeo showed up to a 31% reduction in nocturnal hypoglycemia compared to their popular basal insulin Lantus, whose patent expires this year. 2015 may well be the start of a new era of connectivity… or a lesson learned in who really owns our data. I think this is worth mentioning because US Medtronic CGM users are likely to have access to the Enlite 2G long before the 640G pump even enters trials in the US.
When I started using an insulin pump about 8 years ago I was impressed at the freedom it gave me. I am looking at going on a pump again but truth be told, no pump is THAT different from my OLD Diesetronic D-Tron.
They could develop it with CGM too (unfortunately continuous glucose monitoring is missing from OmniPod`s device). Just for information, GlucoWatch B2 Biographer was developed in 2002, though the same technology was available 30 years before too but because of various reasons (everybody can imagine why) could not became popular..
General consensus exists for an indirect measure of body fatness, called the weight-for-height index or body mass index (BMI).
Maximum lift capacity of 450 pounds, it comes with a six point cradle which may be used with four point and two point slings. The on-board Jumbo actuator pump with emergency button can switch to manual mode to lower the patient down safely with its wide base providing added stability. Maybe she asked about my pump, maybe I had to boost my blood sugar, I can’t even remember how she found out about my largely invisible illness.  But I will never forget that question and the way it made me feel.
She was avoiding exposing her diabetes to coworkers.  Of course, this made it difficult to manage her blood sugar during busy hours at work.
But shame means we think something is wrong with us, that we are broken or unworthy.  That belief is much harder to address.
I recently read a beautiful essay by a mom of a boy with Type 1 and she wisely noted that outsiders are most admiring when you look like you have everything under control.
Also in November, J&J Animas finally received US FDA approval of their Animas Vibe Dexcom-integrated insulin pump that has been available in Europe since 2011 and will start shipping in January 2015.
With the same active ingredient as Lantus, Toujeo will have a flatter profile, a longer duration of action (which will help account for the problematic half-life of Lantus which results in the need for some patients to split doses), and could mean fewer injections and therefore improved adherence from patients. For example, I agree with the last post that it really is inexcusable that there is only one manufacturer with a tubeless pump. I was later able to talk about the comment with my family, and their indignation confirmed my feelings about it.  I like to think that if someone made a comment like that again about diabetes, I would assert myself and simply communicate directly about how it makes me feel. Another player in the CGM business, Abbott Diabetes, received the CE Mark for their new FreeStyle Libre Flash Glucose Monitoring system in 2014.
Details are non-existent (schematics and other sensitive data are protected from public consumption), but there is certainly a filing with FCC that makes us speculate. I do appreciate my pump and what it does for me, but I’m looking for the next best thing.
There employees are rude and not helpful and I have had many problems with my pods and insulin pump. Therefore, since no study done yet, side-by-side comparison of a large group, I am willing to try.
Scientists can develop new iPhone for every year but they cannot develop watch for continuous glucose monitoring?
There seems to be an overwhelming support for Dexcom, however, which makes me wonder if they really are superior or if there is some bias created by the number of sites on the web in Dexcom’s favor????



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