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Nicholas, a 43-year-old man, presented to a regional hospital with a first episode of severe central chest pain. Nicholas was taking an angiotensin receptor blocker for arterial hypertension, but denies a history of dyslipidemia, previous smoking, diabetes, and cardiovascular disease. Dr Frank proposed an association between the bilateral earlobe crease and premature cardiovascular disease, as well as hyperlipidaemia, diabetes and hypertension, due to its high incidence in patients seen in the coronary care unit.
Dr Stefan Buchholz is consultant cardiologist at Mackay Base Hospital, Queensland; and associate professor at James Cook University School of Medicine and Dentistry, Queensland.
Isunado T, Ito I, Katabira Y, et al: Histological study on the ear-lobe crease (in Japanese).
The content on this site is only available to health practitioners registered to practice in Australia.


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Nicholas was given sublingual glyceryl trinitrate oral spray, which relieved the pain completely within less than 10 minutes. There was a family history of heart disease, with his father requiring angioplasty in his late 50s. Given this, his young age, and the fact that he is suspected to have premature coronary artery disease on account of a positive family history and his response to sublingual glyceryl trinitrate, we proceeded directly to diagnostic invasive coronary angiography.
Diagonal ear lobe creases are associated with shorter telomere in male Japanese patients with metabolic syndrome: a pilot study.
Diagonal Earlobe Crease as a Marker of the Presence and Extent of Coronary Atherosclerosis.


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We acknowledge the challenges faced by general practitioners within the complex Australian healthcare system, and use our voice to enhance the work and lives of GPs and their patients. Arterial Doppler ultrasound exams are used to rule out whether pain and numbness are from poor circulation.
This demonstrated severe triple vessel coronary disease, and Nicholas is currently awaiting coronary artery bypass grafting. We inform, educate and engage Australian GPs about all aspects of their professional lives, foster the GP community, lead discussion and work for a strong general practice. Patients who have a history of diabetes, smoking, and high cholesterol may also experience leg numbness or cold feet. Increased All-Cause and Cardiac Morbidity and Mortality Associated with the Diagonal Earlobe Crease: A Prospective Cohort Study.



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