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Researchers at the University of Sheffield have shed light on the possible causes of “Dead in Bed” syndrome, a condition that can see healthy young people with type 2 diabetes suddenly die in their sleep.
Professor Simon Heller of the University of Sheffield’s Department of Human Metabolism, said that the breakthrough research had found that low blood sugar levels during the night can cause prolonged periods of heart rhythm disturbances. Few of the patients taking part in the present study reported symptoms of low blood sugar levels or irregular heartbeats.
Professor Heller said: “We don’t want to alarm patients, but what we’ve found is potentially important in explaining a possible mechanism by which low overnight blood sugars lead to prolonged, slow heart rates. Professor Heller warned that people with type 2 diabetes should be “aware of the risk of running low sugars overnight, particularly if they have known cardiovascular disease”.
He also advised patients with diabetes to check their blood glucose levels late at night every so often or to speak to their doctor about changing their insulin regime.
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Stem cell researchers at Harvard University have developed a treatment that does not require an injection of insulin for the first time.  Doug Melton, the Xander University Professor at Harvard University, who led the work, hopes clinical trials can be carried out on humans within a few years. In a discovery being called a giant leap forward, scientists have figured out how to turn stem cells into insulin producers. There is a new breakthrough from scientists that have developed a computer program that will screen for diabetic retinopathy, a condition that affects some with diabetes. The leading cause of adult blindness is from diabetic retinopathy, which is an eye condition stemming from diabetes which can be treated if diagnosed early.
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In a world first, British children with type 1 diabetes have successfully been entrusted to use pioneering artificial pancreas technology all by themselves at home overnight – without the careful supervision of expert researchers.


The University of Cambridge-devised artificial pancreas promises to dramatically improve quality of life of people with type 1 diabetes, which typically develops in childhood.
Participants, all aged between 12 and 18, saw improved blood glucose control during the trial, experiencing fewer nights with hypoglycaemic episodes, generally known as hypos.
The figure of ten hypos per week has emerged through a first ever real-time information haul of more than 10,000 UK residents with type 1 diabetes, released to JDRF from the mySugr app. All previous artificial pancreas trials, in hospitals and in home environments, have seen researchers strictly monitor patients. Hollywood actor Jeremy Irvine, who is a JDRF supporter, has lived with type 1 diabetes since the age of six. Television presenter Dominic Littlewood gave his reaction to the statistic showing that UK people with type 1 diabetes are having 10 hypos a week.
Dr Roman Hovorka from the University of Cambridge is leading the UK effort to develop an effective artificial pancreas. Katharine Barnard, from the Human Development and Health Academic Unit at the University of Southampton, worked with Dr Hovorka on the trial to evaluate psychosocial impact. Karen Addington, is UK Chief Executive of JDRF, the type 1 diabetes charity which funded Dr Hovorka’s study.
About the artificial pancreas: The artificial pancreas aims to replicate the insulin-producing functions of a healthy pancreas.
The symptoms were only detected by the medical equipment at the University which was able to track blood glucose levels and heart rates. What this means: The 3 million Americans with Type 1 diabetes may be able to ditch the daily injections that keep their blood sugar in check. This research has been shown at the 2014 Association for Research in Vision and Ophthalmology (ARVO) and has let the medical field and fellow scientist review its capabilities and technology.


This new technique will assist in the number of screenings and will take the place of other dated testing. The latest trial, coordinated by the University and funded by JDRF, has shown for the first time globally that unsupervised use of the artificial pancreas overnight can be safe – while also providing exciting benefits. A hypo occurs when the blood glucose level of someone living with type 1 diabetes falls dangerously low. It follows the recent revelation that nine per cent of all hospital admissions for children and young people with diabetes are due to hypos*. News of the successful unsupervised trial has had a positive response from UK celebrities that live with type 1 diabetes. Ten hypos a week is a shockingly high figure, demonstrating just how much we need the artificial pancreas to become an accessible reality.
It is designed to provide exactly the right amount of insulin to the body, exactly when it’s needed.
I wanted to play my own very small part in moving the artificial pancreas closer to reality. The University of Cambridge team in charge of this study only saw the findings from the trial when patients submitted their data in weekly intervals over three weeks – making it the first unsupervised trial.



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