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Healthy People 2010 identified overweight and obesity as 1 of 10 leading health indicators and called for a reduction in the proportion of children and adolescents who are overweight or obese, but the United States has made little progress toward the target goal.
Results from the 2007-2008 NHANES, using measured heights and weights, indicate that an estimated 16.9% of children and adolescents aged 2-19 years are obese. NHANES used stratified, multistage, probability samples of the civilian noninstitutionalized U.S.
2 Data for 1963-1965 are for children aged 6-11; data for 1966-1970 are for adolescents aged 12-17, not 12-19 years. NOTE: Obesity defined as body mass index (BMI) greater than or equal to sex- and age-specific 95th percentile from the 2000 CDC Growth Charts. Back in 2008, I began writing about the effect of dietary fat on insulin sensitivity, and blood levels of glucose and insulin.
Over the years I learned that saturated fat decreased insulin sensitivity more than other fats, e.g.
One mechanism by which dietary fat decreases insulin sensitivity, raising blood glucose and insulin levels is through reduced action of the glucose transporter GLUT4.
Rats fed a high (50% of calories) fat diet for 8 weeks showed 50% decreases in insulin-stimulated glucose transport.
Subjects were deprived of dietary fat (via gastric surgery that decreases predominantly fat absorption). Mice that were fed a high-fat diet and that became obese were protected against insulin resistance and the high glucose and insulin levels of their counterparts when they were bred to have more GLUT4. That reduction in endothelial NO (NO is nitric oxide) production contributes to high blood pressure. This entry was posted in Diabetes, Fat and Oil, Insulin Resistance, Saturated Fat on June 5, 2014 by Bix. Bix Saturated fat is one of our best sources for environmental pollutants, a confounder not adjusted for here.
Fanatic Cook by Bix is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Deregulation of epigenetic profiles has been described in several human pathologies, including complex diseases (such as cancer, cardiovascular and neurological diseases), metabolic pathologies (type 2 diabetes and obesity) and imprinting disorders. However, in recent years we have accumulated some evidence about the role of germline mutations of epigenetic modifiers and their contribution to the development of human diseases. Evidence is mounting of the involvement of genetic mutations of genes related to DNA methylation, such as Rett syndrome (due to mutations in the methyl-binding domain protein MeCP2) and Immunodeficiency Centromeric instability Facial syndrome 1 (ICF1) (due to mutations in the DNA methyltransferase DNMT3). Until now, we had identified genetic mutations that could change the epigenetic patterns; but we still do not understand which are the altered putative downstream genes (epigenetically regulated) that result in specific clinical phenotypes. Medgadget was skeptical about this device, but acknowledged that if successful it can tale over the blood prick market for diabetics. Since fenugreek seeds have been comprehensively researched and offer such a wide range of health benefits for diabetics, they should become a staple in an insulin resistance diet. Despite all of the amazing benefits they offer, it is best for pregnant women to avoid consuming them. Nevertheless, non-pregnant women as well as all men with type 2 diabetes or insulin resistance should consume fenugreek seeds on a daily basis due to the extensive research-based proof that supports them. For more strategies to help you overcome type 2 diabetes, please get a copy of Your Complete Type 2 Diabetes Treatment Plan. This entry was posted in Food & IR and tagged blood glucose, blood sugar, diabetic nephropathy, fenugreek seeds, type 2 diabetes. February 27, 2013 by Renee 1 Comment ***My son is having his surgery this morning and I thought it would be an excellent opportunity to have my first guest blogger! February is National Heart Month, and what better time than now to work together with your own family to prevent your own children from developing Type 2? Celebrate National Heart Month by Developing Healthy Eating Habits ?Since obesity is one of the main factors in the development of Type 2 Diabetes, it is imperative to eat healthy and maintain a healthy weight. Here is a recipe that my cousins love:??Combine one cup vanilla soy milk, one-half cup rolled oats, one sliced banana, and 14 frozen strawberries in a blender and blend until smooth. When you’re running errands all day it can seem easier to just pick up something quick at the store or the ever-conveniently located fast food joint.
This one is simple: high-fat foods lead to obesity and increase your child’s chances of developing diabetes. Choose to give your kids water and 100 percent fruit juice instead of soda and other sugar-filled drinks.
Kids feel like they are getting away with something when mom and dad let them play video games for an hour a day.
Carolyn is a 20-something year old with a passion for life, fitness and overall well-being. Balancing healthy-living as mother, wife, employee, business owner and friend takes all the help you can get let me be a resource for you! A dermal ulcer is a sore that develops on the skin followed by destruction of the tissue surrounding it.
Your first inclination of any compromised skin areas should come if you notice an area where the skin has an increase in redness and warmth, as compared to the skin around it.


Depending upon the extent to which you are affected will determine the stage of your dermal ulcer and the treatment that will be implemented to relieve your discomfort and work to resolve your ulcer. Your doctor will diagnose your dermal ulcer according to the criteria above to develop a treatment plan for you to cope in your day to day life.
Lantiseptic Skin Protectant is a unique high-lanolin emollient ointment intended to protect chafed or ulcer-prone skin, promote the healing of skin injuries and serve as a first aid treatment. The Med Aire Variable Pressure Pump and Pad is made for distributing pressure points helps alleviate bed sores and other discomforts associated with constant pressure on the skin. Mepilex Border is an all-in-one foam dressing that effectively absorbs and retains exudate and maintains a moist wound environment. You can take it upon yourself to decrease your risk of developing a dermal ulcer, which you should definitely try first to avoid more invasive and costly measures. Reposition yourself frequently to enhance blood flow and reduce the amount of pressure that is being put on certain skin areas. Ultimately, dermal ulcers can range from being very minor to causing several complications.
Progress toward reducing the national prevalence of overweight and obesity is monitored using data from the National Health and Nutrition Examination Survey (NHANES). In NHANES III (1988-1994) there was no significant difference in prevalence between Mexican-American and non-Hispanic white adolescent boys. There seems to be both a reduced expression of the GLUT4 gene, and a reduced translocation or movement of GLUT4 to the cell membrane in the presence of a high-fat, especially high-saturated fat diet.  (GLUT4 is one of the glucose transport proteins that move glucose from the bloodstream into muscle and fat cells. When normal amounts of insulin fail to clear blood of glucose, the pancreas responds by releasing more. Also, the fat we eat can change the composition of lipid in cell membranes.  A diet high in saturated fat has been shown to make membranes less fluid and may impair GLUT4 insertion. There really is abundant research on the role of dietary fat in the development of insulin resistance, a condition which manifests as elevated glucose, elevated insulin, and the development of type 2 diabetes. Deleterious epigenetic profiles could be a consequence of mutations in the “writers” “erasers” and  “readers”, that is to say, dysfunctional enzymes that are responsible for putting in and out the epigenetic marks and for their cellular interpretation. Most of these disorders are included under the term “rare diseases” – any disease that affects a small percentage of the population (although there is no general consensus about what “small percentage” exactly means). In contrast to the limited number of mutations affecting DNA methylation, the huge number of rare disorders that could be associated with mutations in histone modifiers and chromatin-remodelling proteins must be highlighted. Most importantly, we are still in the infancy of the understanding of how such epigenetic defects (potentially reversible) could provide a target for therapeutic intervention. Moreover, clinical laboratory studies show that there is a quantitative correlation between glucose content in blood and acetone concentration in the exhaled air. One thing is for sure, there is big market for glucose monitors for diabetic patients that companies can tap into.  Whichever company can eliminate the pain of pricking the finger could sweep the market, if product is affordable to the consumer. They have been studied extensively and the range of health benefits they offer, particularly for diabetics, make them an essential part of an insulin resistance diet. A study with mice found that consuming fenugreek seeds impaired sensorimotor development and the operation of spinal cord networks. It was National Diabetes Month, and ironically, it was the same month that we found out that one of my younger cousins was diagnosed with Type 2 Diabetes. According to Syracuse’s Cardiac Hospital, there are currently 215,000 children under age 20 that are diagnosed with diabetes, and this number is growing at an exponential rate.  What’s more, there are seven million people who are unaware that they even have the disease! Healthy eating habits can help to keep blood glucose and insulin levels stabilized and prevent diabetes. Smoothies are a great way to make sure that kids get the right amount of daily fruits and veggies, but they are also fun to make and delicious!  Smoothies are also great because they can be served as breakfast, a snack, or even desert! Common options for team sports include: football, basketball, soccer, cheerleader, gymnastics, tennis, softball, and volleyball.
Gather neighborhood kids together to play soccer, tag, capture-the-flag, “cops & robbers,” etc. If you’re able to, play with your kids on the jungle gym – you’d be surprised at how quickly it all comes back!
She is an avid cycler, golfer and has been known to bust some serious moves on the dance floor.
Tissue destruction leads to complete loss of skin; the size and depth of the ulcer depends on the severity of what exactly is causing it. This should warrant immediate medical attention to determine any possible underlying causes in order to reduce your chances for more complications or recurring skin issues. The main goals of treatment for dermal ulcers are aimed at avoiding any possible infection that could occur, maintaining an overall moist environment for healing, and easing any pain. It is formulated to encourage the proper moisture balance of the skin, thereby supporting the body’s natural healing processes. The Safetac layer seals the wound edges, preventing the exudate from leaking onto the surrounding skin, thus minimizing the risk for maceration. There are special pads, mattresses and hospital beds alike that can prove to relieve pressure either on good skin or those areas that already have a dermal ulcer present. Healthy diet habits can keep you at a healthy weight and decrease your risk for more chronic conditions that could lead to inadequate circulation and formation of dermal ulcers.


You know your body the best, so at the first sign of your skin showing an abnormality do not hesitate to consult with your provider just to be safe.
Between 1999-2000 and 2007-2008, there was no significant trend in obesity prevalence for any age group. Based on current recommendations of expert committees, children with BMI values at or above the 95th percentile of the sex-specific BMI growth charts are categorized as obese. A household interview and a physical examination were conducted for each survey participant. The result is impaired glucose tolerance, hyperinsulinemia, and eventual development of type 2 diabetes.
As the most studied example, more than 40 de novo recurrent disruptions of several genes encoding components of the epigenetic machineries are typically observed in many tumors [1].
Homozygous mutations affecting epigenetic enzymes are lethal reflecting the vital role of epigenetics in normal development and differentiation.
Why this frequency?  There is not clear explanation; however, it could be associated with the overlapping function of histone modifiers in specific residues. The possibilities have only just begun to be explored in human patients, but the basis of this therapy has been confirmed in animal models. The Easy Check breath glucose test measures the levels of acetone in a patient’s exhaled breath. It was a shock to our whole family – we knew she had some serious weight challenges, but I never believed that she could develop such a serious disease as diabetes. If we want to ensure our children live long, healthy lives, its up to us as parents and family members to do all we can to prevent it. Pack healthy snacks ahead of time to ensure that you have good foods on hand when the kids (and you, too!) start to get hungry.
Sports are a great way for kids to get exercise without realizing they are exercising, and sports also provide great life and social lessons, too! Keep in mind also that serious complications, such as infection of the bone or blood, may occur if the dermal ulcer progresses without treatment. It can safely support anyone up to 250 pounds and do wonders to increase circulation and reduce the incidence of decubitus ulcers.
The Safetac layer ensures that the dressing can be changed without damaging the wound or surrounding skin or exposing the patient to additional pain. Prevention of infection and pain can be managed with several different medications such as antibiotics, muscle relaxants and non-steroidal anti-inflammatory drugs such as Aspirin, Advil, and Motrin for example. Good exercise regimens can keep your blood flowing and help you also maintain an optimal weight. This is different from previous years where children above this cutoff were labeled overweight.
During the physical examination, conducted in a mobile examination center, height and weight were measured as part of a more comprehensive set of body measurements.
Over time, compensatory insulin output from beta cells in the pancreas diminishes and a person with type 2 diabetes may find themselves injecting insulin instead of just taking oral meds. However, an increasing number of heterozygous mutations during early development have been identified, especially in diseases affecting intellectual disability [2]. After talking to numerous doctors and doing our own research, we vowed as a family to work together to get my cousin healthier, and to take better preventative measures to make sure no one else in the family developed this disease as well. This change in terminology reflects the labels used by organizations such as the Institute of Medicine and the American Academy of Pediatrics. These measurements were taken by trained health technicians, using standardized measuring procedures and equipment. The nervous system represents an immensely complex structure in which the orchestrated control of gene expression (partially due to epigenetic control) faces its major challenge. As new members of the epigenetic machinery are described, the number of human syndromes associated with epigenetic alterations increases [6].
The understanding of the contribution of epigenetic change to rare disorders and common neurological disorders will hopefully provide us with better molecular tools for an improved diagnosis, prognosis and therapy of these patients in the future. Standard lays on top of your mattress, deluxe has flaps that help hold the pad securely in place. Observations for persons missing a valid height or weight measurement or for pregnant females were not included in the data analysis.
Some interesting data: 3 of 4 genes are expressed in the brain [3], and it expresses more alternatively spliced transcripts [4] and miRNAs [5] than any other tissue. As recent examples, mutations of histone demethylases and members of the non-coding RNA machinery have recently been associated with Kabuki syndrome (mutations in JMJD3), Claes-Jensen X-linked mental retardation syndrome (JARID1C mutations) or Goiter syndrome (DICER mutations). The complexity of the nervous system makes it especially sensitive to epigenetic disturbances, and consequently, many mental disorders are caused by mutations in the epigenetic machinery. Although this cutpoint is not diagnostic, elevated BMI among children indicates increased risk for future adverse health outcomes or development of disease.



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