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The purpose was to finally demonstrate whether or not good blood sugar control was really important to prevent the complications of diabetes.
For you, a person with type 1 diabetes, lowering your A1C by 1 per cent means a 45 per cent less risk you will develop the chronic complications of diabetes! Cellulitis is an inflammatory condition involving the deeper layers of the skin – dermis and subcutaneous tissue. Although cellulitis may develop following an injury to the skin or around a surgical wound, in some cases there may not be any apparent break in the skin.
Chronic edema or swelling of the leg and pre-existing skin conditions such as athlete’s foot, impetigo, or eczema may be risk factors for cellulitis. If left untreated, cellulitis can lead to serious complications, particularly in patients with diabetes, cancer, and those with decreased immunological status. Hypertensive retinopathy is the damage to the retina and retinal circulation due to high blood pressure. HIV causes a breakdown of your body’s immune system, all areas of the body are susceptible to infection, including the eye. Inflammatory disease that damages nerve coverings, causing weakness, coordination and speech disorders. The condition of gangrene is a serious one, primarily marked by loss of adequate supply of blood to the tissues of the body, ultimately resulting in its necrosis or death. Injury to the tissues, infection (mostly of bacterial origin) and presence of any underlying health ailment that inflicts damage to the blood carrying vessel structure form the three key underlying mechanisms that are responsible for initiation and development of irreversible tissue damage and life threatening condition of gangrene. As already explained, one of the causes of gangrene in the toes and fingers is linked with damaged blood vessels.
High level of blood glucose associated with diabetes mellitus also damages the nerves (known as peripheral neuropathy), especially the nerves in the lower extremities.
The dullness or lack of sensation puts diabetic individuals at an increased risk of injuring the skin of their fingers or feet without having any realization (it mostly goes unnoticed in the feet region). The sore or foot ulcer formed takes an extended time to heal because of both, poor circulation of blood through the injured area as well as lesser number of defence cells. Bacterial infection also forms another causative factor that makes the diabetic individual more prone to developing gangrene.


Such type of infection is marked by noticeable skin discolouration and dryness along with the formation of skin blisters. The weakened immune system (seen in diabetes) further raises the risk of incurring serious infection, which later develops, into gangrene. And indeed it is a€“ as you can see below, complications developed at a much lower rate in the intensively treated group compared to the conventional group.
Early and optimal blood glucose control has long term benefits.Thata€™s why we believe so passionately in using the IT system, and why we want to help you find the best way for you to do this.
Cellulitis caused by methicillin-resistant Staphylococcus aureus (MRSA) may need more aggressive treatment. Microabrasions of the skin due to dry skin may also serve as an entry point for the bacteria causing cellulitis.
Similarly, conditions such as diabetes, obesity, chronic kidney disease, chronic liver disease, and pregnancy may be predisposing factors in the development of cellulitis.
It reaches the deeper layers and multiply there, thus giving rise to symptoms of cellulitis. Complications may include blood or bone infections, shock, meningitis, lymphangitis, endocarditis and gangrene. Initial symptoms can include vision fluctuations as blood sugar levels fluctuate, change in prescription in your spectacles (myopic shift). AIDS related eye problems include retinal ischemia causing cotton wool spots, and more seriously CMV retinitis.
Death of cell and tissue may target any part of the body, however, it has been typically observed in the extremities, such as the toes, fingers and hands. In both, type 1 and type 2 diabetes, the raised level of sugar is capable of causing damage to the blood vessels and reducing blood supply.
Owing to the nerve damage, the transmission of sensation, particularly those of pain to the brain gets impaired. A notorious bacterial organism, Clostridium perfringes is often linked with gas gangrene; after it attacks the site of injury or sometimes, surgical wound. Cellulitis tends to arise in the periphery of the body, more commonly on the legs and less frequently in the arms.


Less commonly, other types of bacteria such as Hemophilus influenzae, Pneumococcus, and Clostridium species may also cause cellulitis.
The typical features of inflammation may be seen in cellulitis, such as pain, warmth, redness and swelling of the affected area. Long red streaks may indicate involvement of the lymphatic system. Cellulitis may be confused with erysipelas, which is a more superficial skin infection, with well-demarcated, slightly raised borders.
Longer treatment may be necessary if the condition is very severe and in immunocompromised individuals. In the absence of a continuous supply of nutrient and oxygen rich blood, the cells within the body begin to fail in carrying out their normal function and finally give up. As a result of restricted blood circulation to the extremities, such as the feet, the area becomes deprived of those cells (white blood cells) which aid in fighting off any infection. For example, kidney and eye disease may stay stable for years!At the end of the original DCCT trial, all the people in the conventional group changed to intensive therapy and their A1C lowered. Some of the bacteria responsible for cellulitis may be harmless strains normally present on the skin, in the nasal cavity or the mouth. Swelling and inflammation resulting from the infection causes the local temperature of the area involved to be slightly elevated, and also leads to pain. Although cellulitis is easily treated with antibiotics, it is a serious medical condition that can quickly progress and lead to complications and even death. Others may be transferred from the environment, water, or other contaminated objects. However, cellulitis is not contagious.
Infection on the face may spread quickly and lead to meningitis, a very dangerous complication of cellulitis. Now thata€™s commitment to a research study!Over time the A1C of the original intensive therapy and the former conventional therapy groups evened out at an average of 8%, but the benefits of intensive therapy remained a€“ much to everyonea€™s surprise.



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Comments

  1. BI_CO

    Vegetables, low-sugar fruits (such as strawberries.

    02.05.2015

  2. QARTAL_SAHIN

    The goal is to keep blood sugar even by eating then fry half a complications of diabetes in cats pink onion cut causing headaches.

    02.05.2015