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One simple way to cut down your risk by 22% is to limit or, even better, eliminate sugary drinks.
Discolored toenails may be due to a fungal infection, or a symptom of a medical issue such as diabetes. Discolored toenails that are also painful or difficult to maintain may need to be checked out by a podiatrist. Public bathrooms pose a risk of a toe infection, particularly to people who walk barefoot through them. If a bald eagle loses a feather on one wing, it will drop a matching feather on the other side to maintain balance. The most common causes of discolored toenails are fungal and bacterial infections, but bruising and bleeding under the nail might also be to blame. Fungal spores are pretty common, and they’re found in most places, from soil and dust to food and waste. Bacterial infection also can discolor toenails, and nails with this sort of infection will typically soften and take on a green color. Minor discolorations or changes in color and texture that happen slowly over time might be an indication of a much more serious medical condition. Most medical experts recommend that anyone who notices changes in their toenail coloring, no matter how minor it may seem, get the problem evaluated to rule out serious conditions.
Women should always remove their toenail polish before going to the doctor, especially for a physical. When you have underarm rash it is usually not conspicuous but it can be an annoying and discomforting condition, especially if it begins to itch and makes the area flaky and dry. Because underarm rash is a symptom you may also experience other symptoms that depend on what is causing the underarm rash in the first place.
Rash may cause bumps that are filled with pus, flaky, scaly, or have a bumpy feeling to them.
Having the skin disorder that causes blistering or scaly rashes that could be caused by an allergy called eczema.
Having an inflammation of your hair follicles that could happen after you shave called folliculitis. Fungal infections that come from not cleaning the sweat, dirt, and other stuff under your arm on a daily basis.
Having an allergic reaction to something is the most common cause of having an underarm rash.
Having a disorder in which your body attacks its own healthy tissues and cells called systemic lupus erythematosus. If the underarm rash is caused by an allergic reaction to soaps, shaving cream, detergents, deodorant, perfume, etc, change what you are using until you find one that does not cause underarm rash.
If it is due to folliculitis you will need to see your physician for a prescription of a topical cream to help reduce your discomfort and help calm down the inflamed follicle. If it is due to a fungal infection you will need to apply antifungal creams to the area and also decrease the amount of milk-products and milk you are consuming. If the cause is shaving, make sure that you are using a new blade or razor and try a shaving cream or gel for sensitive skin.
Do not wear tight clothing, especially in the heat, as this can cause friction under your arms. Make sure that you are keeping your underarms dry and clean by washing under the area at least two times a day. If your underarm rash is caused by a medical condition talk to your physician to see which treatment would work best for your condition. This website is for informational purposes only and Is not a substitute for medical advice, diagnosis or treatment.
At its root, adult acne is caused by the same things that cause teen acne: excess skin oil and bacteria. Wash your face twice a day and after sweating, using a mild cleanser and warm water -- not hot water.
Sugary or greasy foods hinder your health in other ways, contributing to diabetes and heart disease.
A dermatologist can work with you to develop a treatment plan for your acne and unique skin type.
Medicated creams with benzoyl peroxide, salicylic acid, or alpha-hydroxy acid are the first treatments to try. Your doctor can prescribe stronger creams, or other medications that help, such as antibiotics, oral retinoids, androgen blockers, and low-dose birth control pills. Ingrown toenails problem can turn worse by wearing tight shoes that press against the flesh harder. At the center of the hemoglobin molecule is a heme group, with an iron atom at the center of it. As it goes through the body, hemoglobin gives up its oxygen to the various cells it comes in contact with.
When this wonderful oxygen transport from your lungs, through your heart to the rest of your body is messed up for some reason, you have anemia. I used one of my own prior CBC reports to illustrate white blood cell counts in my last article. If I were a CLL patient with red blood cell issues, RBC can be much lower than these healthy reference ranges. Anemia is easy to diagnose but not as easy to explain since it can be caused by many different things. Once again, I cannot over emphasize the importance of not getting fixated on any one number but looking for overall trends. MCHC is the average hemoglobin concentration of packed red cells expressed as a percentage. In CLL patients with sharply lower RBC – perhaps because of AIHA or some of the other reasons discussed below, the bone marrow will register this fact and try to compensate by producing more red blood cells to replace the ones being lost. There are specific reasons for anemia in CLL, over and above the general reasons (poor diet, physical blood loss etc) discussed above. When the problem is too few red blood cells, patients are transfused with “packed red cells” – not whole blood.
The risk of infection using standard issue packed red cells is trace levels of viruses (hepatitis is one of the biggest risk factors) that can hide out in the donor white blood cells. Irradiated and leukoreduced blood products are a tad more expensive than the garden variety blood products, but not prohibitively so, and definitely not as expensive as the complications patients can run into if the wrong products are used. As with most things, too frequent red blood cell transfusions carry the risk of iron overload. You are right that poikilocytosis is the term given to somewhat mis-shapen red blood cells. There are many different reasons why red blood cells can be misshapen, not all of them well understood. I listed Vitamin B1 deficiency in the table under reasons for low hemoglobin, therefore anemia.
About two weeks ago my Hemoglobin went rapidly down to 7, so I needed a transfusion to get a better one. I read that erythrocyte concentrates are the better the newer they are and that older ones are from a poorer quality and in so far bad for hosts.
Blood banks have very strict guidelines on how long they can keep blood products before they are past their shelf life, so I would not worry about it. LynnS: My maternal grandfather died, like your mother, of complications of aplastic anemia after 6 years or so of blood transfusions. Both my primary care and Oncologist recommended low dose asprin therapy for me as a preventative step to future cardiac events. Low dose aspirin is likely a good thing to do except for those with aspirin allergy, very low platelet counts or problematic coagulopathies such as Von Willebrands disease, hemophilia, etc. I would love to know more about the spleen and liver and how it copes with a huge mount of lymphocytes eg: 200K. You do a great service in guiding us in the art of knowing when to panic and when to wait out the lower or higher than normal numbers on our blood work and what it all means.
CLL Topics Updates does not provide medical advice and its contents are for information only.


It has been fifteen years since the FDA approved the use of Viagra for the treatment of erectile dysfunction (ED). For us Suddenly Solos, it is important for us to understand the impact of using any ED medication as it applies to our partner. There is also a misconception that Viagra causes not just greater blood flow but also greater desire. Fifteen years and many studies have shown that Viagra (and most other EDs) are effective and safe when used as directed. Diabetes type 1 is a disease in which a person is born with a body that simply does not produce insulin.
These are people who are fighting to find a cure for diabetes or want to spread awareness of the disease. Studies show that even one sugary drink a day can increase your chances of getting diabetes. Extremely obese people will have a 70% less chance of getting diabetes if they lose just 5% of their weight. First, increasing your whole grain intake can  help you lower your chances of getting diabetes.
Look on the ingredient list for sugars with these names: brown sugar, corn sweetener, corn syrup, dextrose, fructose, high fructose corn syrup, invert sugar, maltose, malt syrup, molasses, sugar, and sucrose. In some cases discoloration is an indication of a much more serious condition, like diabetes, liver failure, or heart disease. Fungi are small strains of mold or other parasitic cells that invade a host and essentially use it as a breeding ground.
Warm, moist, and humid environments cause them to thrive, and as a result pools, shower rooms, and public bathrooms pose an increased risk, particularly to people who walk barefoot through them. Regularly rotating shoes can reduce the chances of developing an infection that might cause discolored toenails, and people who are very concerned about infection might go so far as to select shoes that are vented or that otherwise allow air to flow in order to prevent moisture from collecting.
In most cases, these happen as a result of an injury or trauma that has left part of the skin or nail bed exposed to outside elements. This most frequently happens because of a stubbed toe, something heavy that has been dropped on the foot, or an ingrown toenail. Diabetes and several liver ailments can cause color changes in the finger and toenails, for instance, as do heart disease and some forms of kidney failure.
If over-the-counter fungal creams do not take care of the problem you will need to talk to your physician about a prescription for a stronger antifungal medication.
Any changes in hormones, including those brought on by pregnancy and menstruation, can trigger excess oil.
If you do want to use foundation, some dermatologists recommend oil-free liquid silicone matte foundations, such as those containing dimethicone or cyclomethicone. Touching your face can increase oiliness, irritate your skin, and encourage the growth of bacteria.
Use your fingertips (not a washcloth or sponge) to wash your face with a non-abrasive cleanser.
Cutting the edges of toenails sharp and straight will inhibit them from growing into the skin. The cotton should not be big making it stick out from the toenail at the same time ensure that it is not too small either. You accept that you are following any advice at your own risk and will properly research or consult healthcare professional. Since anemia is a common side effect of CLL and causes significant loss of quality of life, we need to learn about it.
Over the years I have seen many thousands of patient CBC reports, people seem to like sending me stuff and ask me to read the tea-leaves. Take out all the water in the red blood cells and pretty much the only thing left is hemoglobin.
We said if you take a tube of fresh blood and spin it around fast in a centrifuge, the red blood cells will settle to the bottom and that this layer is just under half the volume of blood in the tube. There is a range of sizes in red blood cells, not all of them are exact copies of each other. It is a derived number, you can calculate MCH by dividing the total amount of hemoglobin by the number of RBC, then multiply by ten to make the units work. You can calculate it by dividing the total amount of hemoglobin by the hematocrit, multiply by 100 to get percentage. Many of the chemotherapy drugs used to treat CLL are “myelosuppressive” – meaning they damage or reduce the production capacity of stem cells to produce more myeloid cells – red blood cells are part of the myeloid line. The only choices at that point are stem cell transplant with healthy stem cells from a willing donor, or a lifetime of blood transfusion dependency. These are chemical messengers that alert the bone marrow to low RBC; marching orders as it were, that tell the marrow to gear up and increase production. One of the most common autoimmune diseases in CLL is AIHA (autoimmune hemolytic anemia), where perfectly good red blood cells are targeted and destroyed by the body’s own immune system gone berserk.
The red blood cells are separated from blood plasma and from the other cells such as platelets, white blood cells etc by simple process of centrifugation. So, most blood banks recommend using irradiated and leukoreduced blood products for transplant patients as well as patients with any level of immune dysfunction.
I had reason to learn all about this while my husband was going through his stem cell transplant and needed frequent transfusions. Each of those healthy new red blood cells coming into the body carries its own iron atom, and too many transfusions can cause too much accumulation of iron in the body of the patient. The reason for this low Hemoglobin is not yet identified but some reasons like bone marrow infiltration with CLL or autoimmune disease ore some viruses could be excluded.
I am in W&W but this seems counter intuitive as asprin thins the blood and would seem to impact platlets. I have been anemic and you explanation of causes and the meanings of the CBC has been very helpful. A woman’s post-menopause genital health can put her 180 degrees apart from our medically-assisted ardor. But as enlightened males, we should always remember that really good sex is enjoyed by both the participants!
Diabetes type 2 is a disease in which a persons body stops absorbing insulin or there is not enough of it. Sugar and unhealthy body weights are the number one reason diabetes is a problem in our society.
Even if you are not obese but slightly overweight, maintaining a healthy weight will decrease your chances enormously. Many doctors and care providers make an effort to examine patients’ nails during routine check-ups to monitor for problems that may first appear as color variation in the finger or toenails. When these cells get into the toenails, they often cause the nails to turn yellow or brown, depending on the variety or particular strain involved. A smashed toe that isn’t properly bandaged is one example; a pedicure that clips too much of the delicate cuticle tissue or that breaks the skin under the nail is another.
These will usually go away on their own after a time, though it can take a few weeks for the trapped blood to be broken down and absorbed by the body.
Blackheads form below the skin's surface, when oil, also called sebum, reacts with air in a partially clogged pore.
Your doctor may choose to treat this severe form of acne with antibiotic pills for a short time. Treatment takes time -- usually 4 to 12 weeks -- and you need to continue it for it to work. People wearing tight shoes, or having poor hygiene of the foot, long toes, short nails, any injury in the toenails, diabetes, abnormal nail growth, excess foot sweating, etc are prone to ingrown-toenails.
If infection is severe, you may need to undergo a surgery to prevent death and decay of tissues. This will not only soften the toenails, but will protect ingrown toenails from infections as well.
Often keep checking that the cotton is in place and replace with another piece of cotton if it falls out. Heck, blood is red because it is full of red blood cells.  Next obvious question, what makes red blood cells red?


When hemoglobin comes in contact with oxygen in your lungs, oxygen gets attached to the iron atom. And as you can see from the reference interval given for healthy individuals, I am doing OK on this front.  Reference ranges are even more important in the case of red blood cells because they are different for men and women. Remember, just because you have CLL does not give you a pass, a get-out-of-jail-free card from all the other things that go wrong with people as they age.
Hematocrit is the volume of red blood cells in a sample of blood, reported as a percentage. For example, newly minted red blood cells are just a bit bigger than older RBC that have been around the block more than a few times. If there is a robust number of new red blood cells being made, as well as old ones hanging around, RDW will be a high number because the range of sizes of the cells present is broad. If there are so many CLL cells in the bone marrow that the ‘factory’ is packed to the rafters with these cancerous cells, there is no room left for healthy production of other cells to make up for losses due to normal wear and tear.
If the damage is temporary in nature, production will gradually recover and RBC counts will head back up gradually. AIHA can be detected by Direct Coombs test and looking for antibodies targeting red blood cells.
While getting any blood product carries some risk of infection, this risk can be minimized by taking proper precautions.
Leukoreduced means they put the packed red blood cells through another step of purification, where the last remnants of white blood cells (“leukocytes”) are removed, since viruses hang out in white blood cells.
You can read the details by visiting “Harvey’s Journal”, the on-line blog we maintained so others can learn from our experience through this difficult period of our lives. But this is not something to worry about unless we are talking of patients who are chronically transfusion dependant.
I will pass this on to my family as well.I tell them knowledge is wisdom and we need all the wisdom we can muster with this disease. It has been one of the most useful aids in helping me and my Doctors see trends in the progression of my disease. Just last year (2012), over eight million prescriptions for the medication were written in the US. A man with little or no testosterone will not have any desire to have sex, with or without ED meds. When yo do eat out, look at the nutritional fact menus that many sit-down and fast food restaurants have and eat as healthy as possible.
At first the discoloration is usually very small, often appearing just as a dot on the surface of the nail.
Strains of bacteria typically enter through broken skin, then begin invading the toenail and surrounding tissues. In these cases nail changes are usually just one of many different symptoms throughout the body, but they are often an easy place to start.
Answer: because red blood cells have a molecule in them called hemoglobin (also spelled as haemoglobin if you are Brit, and abbreviated to Hb, Hgb or Hg) and hemoglobin is colored a bright cherry red when it is rich in oxygen, but more bluish red in color when it has been stripped of its oxygen. After picking up this precious hitchhiker in the lungs the blood next goes to the heart – the pumping station which circulates blood throughout your body. In my case, the hemoglobin level is a tad low, below the reference range for my lab and hence it is flagged. A low hematocrit usually indicates decreased production, excessive loss, or destruction of red blood cells. Cell size can also change depending on dietary issues – B12 and folic acid deficient red blood cells are larger than iron deficient cells. A small RDW number suggests there is no extraordinary amount of red blood cells being made in the bone marrow.
This may suggest that in spite of the obvious and  crying need for increased production of red blood cells, the bone marrow is not able to oblige. The remedy is to clean out the bone marrow with appropriate therapy to kill the CLL cells there. Treatment options include prednisone, Rituxan, chemotherapy drugs, spleen removal – some or all of the above, as it becomes necessary.
It can also be caused by a digestive disease, such as celiac disease, in which case the treatment may be treating the underlying celiac disease. I have used multiple institutions, some of which still log in values by hand on crude charts.
Reduced estrogen levels often mean less sexual desire but also decreased vaginal elasticity and lubrication, and thus more potential for sex to be painful. If things are allowed to progress, though, all nails on one or both feet might change color and even shape, often dramatically. Any blood that doesn’t go away, as well as spots that seem to be growing larger instead of shrinking, should usually be checked out by a medical professional, though, as these could indicate circulatory or other blood problems. Did you know hemoglobin is present to the tune of 95-97% by dry weight of red blood cells (if water is counted, then the weight percentage of hemoglobin is around 35%).
This oxygenated version of hemoglobin is bright red – which is why arterial blood leaving the heart is bright red. I am a bit anemic, possibly due to low level of iron in my food (I am a vegetarian) and poor absorption of what iron there is in my diet due to early stage Crohn’s disease. Perhaps the marrow is choke full of CLL cells and with the best of intentions the marrow cannot produce new red blood cells because of the infiltration, or perhaps the bone marrow is just not getting the message.  More about this further down.
I too have a mild case of poikilocytosis, because of underlying Crohn’s disease (a kind of autoimmune ulceration of the GI tract).
In fact, Viagra’s action was “discovered” as a side effect to its original purpose as a heart medication. According to the American Diabetes Association, “Diabetes causes more deaths a year than breast cancer and AIDS combined. Get answers to popular questions about adult acne.Adult Acne Slideshowwbmd_disclaimer091e9c5e8133bfb0nulldateTHIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. Think of red blood cells as little sacks full of water and hemoglobin and you will be right on the mark. Depleted oxygen supply to the cells is slow suffocation, and that is exactly what it feels like. It is intended for general informational purposes only and does not address individual circumstances. Once the hemoglobin has given up its oxygen to the cells it picks up the waste byproduct of cellular breathing, namely carbon dioxide. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Venous blood returning to the lungs and heart is bluish red in color because hemoglobin with carbon dioxide attached to it is bluish red in color. None of the hemotologists I see or my primary MD seem concerned and I have not gotten much of an explanation for it.
Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site.
Women who smoke also seem to be more prone to acne.Acne tends to run in families, so if a parent had adult acne, you're at higher risk. Non-comedogenic and nonacnegenic products can be better for acne-prone skin. You might also try using powder cosmetics instead of cream foundations.
Effective acne treatment may actually help reduce your stress.However, in some people, stress can worsen acne. However, if it seems that certain foods trigger breakouts, avoid them.Sugary or greasy foods hinder your health in other ways, contributing to diabetes and heart disease. And for some women, acne ends with menopause.Until then, fortunately, there are treatments for adult acne. Oily hair care products can get on your face and clog pores.Third, be gentle with your skin.



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