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Nonalcoholic fatty liver disease (NAFLD) was found in 50% of patients with type 2 diabetes who had normal aminotransferase levels in a recent study reported in the June issue of the Journal of Clinical Endocrinology & Metabolism. The study involved 103 patients with type 2 diabetes and normal plasma aminotransferase levels, and without a prior diagnosis of NAFLD. The prevalence of NAFLD was 56% in patients with obesity and 36% in patients without obesity.
Existing guidelines do not advocate screening for liver-related complications among persons with type 2 diabetes mellitus (T2DM), making the liver a potentially neglected target organ for undetected chronic disease progression to cirrhosis. In clinical practice, it is well known that most patients with T2DM and NAFLD (approximately 80%) have normal serum aminotransferase levels. From the results of this and other recently published studies, I believe that the possibility of NAFLD should be entertained as a part of the routine evaluation of patients with T2DM, in the same way, we search for microvascular and macrovascular complications.
Because of the link between T2DM, NAFLD, and adverse vascular and hepatic outcomes, more careful surveillance of these at-risk patients is needed with the combined use of serum liver enzymes, liver imaging (mainly ultrasonography and Fibroscan, I think, given that proton magnetic resonance spectroscopy, as used in the study by Portillo-Sanchez et al, is too expensive to be used routinely for the screening of NAFLD in T2DM patients), and clinical risk score systems for advanced liver fibrosis.
When the heart is damaged, it can not function well to pump blood effectively and blood will be back to the legs, feet and ankles, resulting in swelling in the feet, ankles and legs. Blood clots and stasis can form in the blood vessels of the legs which will hinder the smooth blood circulation. Reduce or avoid salt intake and replace salt with sodium-free herbs and seasonings while cooking meals. If patients have other symptoms or discomforts besides feet swelling such as fatigue, loss of appetite, nausea, vomiting, shortness of breath, chest pain, it is recommended to see a doctor and seek proper treatment as soon as possible according to the underlying cause.
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Your skin can be a window to your underlying health, says Wake Forest University's Joseph Jorizzo, MD, one of the experts who literally wrote the book on skin signs of internal disease. Lichen planus is a rash made up of reddish-purple, flat-topped bumps that may itch like crazy.
Shagreen patches are flesh-colored lesions on the lower back that have the texture of an orange peel. Tripe palms describes a skin condition in which the skin of the palm becomes thick and velvety-white with pronounced folds in the lines of the hand. First described in 1997, nephrogenic systemic fibrosis starts as a brown discoloration and indentation of the lower arms and legs. The lower edge of the liver normally comes just to the lower edge of the ribs on the right side. There are several symptoms that you should know so that you will be aware if you are having this chronic skin disease. Whenever you are experiences most of these symptoms or even just some, it is best to visit a dermatologist.
Aside from the mentioned information above, this skin problem will show like a rash and it will affect the abdomen, legs, back, arms, and chest.
Most people are looking for a miracle eye cream or gel to apply to the area to improve the appearance of whichever of the above they are experiencing…some even want tried and true home remedies.
In the more preventative and holistically-minded practice of Traditional Chinese Medicine (TCM), most practitioners can look at a person’s physical features, especially those on the face, and get a general overview of the person’s condition. In TCM, puffiness in the eye area is either caused by a pool of liquid or a pool of mucus (yuck); both of which are caused by issues with the kidneys.
The second type, caused by accumulation of mucus and fat directly correlates to built-up mucus and fat in and around the kidneys and other organs in that region of the body. In TCM, a person whose skin color around the eye area does not greatly differ from that of the rest of his or her face is considered to be a manifestation of good overall health and balance.
Dark, bluish circles are typically indicative of problems or disorders with the kidneys, and adrenal and gonad hormones. Redness (which could eventually appear purple) is caused by dilation of the capillaries under the eyes. A yellowish tone in the eye area is directly related to an over-functioning liver and gallbladder. A gray discoloration can not only indicate an issue with the kidneys, but also with the lungs, endocrine and lymph systems, and reproductive system.
In TCM, it is not a person’s genetic patterns that determine eye puffiness, dark circles, or the presence of milia; rather it is one’s “inherited” dietary and lifestyle routines that are responsible.
With this knowledge, it is very easy to understand how the appearance of one’s eyes can reveal overall good health and balance, or point to disorders and disease.
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Rachael Pontillo is the bestselling author of the book Love Your Skin, Love Yourself and co-author of The Sauce Code. My son has what it looks like a wart under his left eye and his skin is turning whiter around that area. I have puffiness in my eye lids and more often than not my right eye in the mornings gets so puffy it is affecting my vision. I have been vegan for 3 years and my diet consists mainly of fresh fruit, green leaves and vegetables, some legumes and a bit of nuts and seeds. I also have some milia and I think that they started to appear in the last few years since i improved my diet. Is Bad Skin Ruining Your Life?You don't need good genetics or even good luck to have great skin--you just need a plan.
You!Check your inbox for your confirmation email--once you click on the link in the email, you'll have instant access to your free skincare class! People who have diabetes, heart problems, kidney or liver disease, and pregnant women are more prone to this problem.As the swelling increases, it can cause general discomfort and people may find it difficult to walk or stand.
Increasing body mass index was significantly associated with a greater prevalence of NAFLD (P=0.001).
Targher is Assistant Professor of Endocrinology and Diabetology at the University of Verona Medical School, Verona, Italy.
Portillo-Sanchez and colleagues have examined for the first time the prevalence of NAFLD and NASH in a relatively large sample of predominantly obese patients with T2DM and normal serum aminotransferase levels.
The finding of this study is consistent with earlier studies showing that the full histological spectrum of NAFLD may be present among patients with fairly normal serum aminotransferases.


Additionally, a multidisciplinary approach to the treatment of patients with NAFLD, based on a careful evaluation of related cardiometabolic risk factors and monitoring for cardiovascular, kidney, and liver complications, is warranted. High prevalence of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus and normal plasma aminotransferase levels.
Renal disease is the most common cause of swelling in the feet, ankles, legs as well as face, hands, abdomen, etc. It can be caused by other conditions such as liver disease, heart problems or infections, etc.
When the liver is damaged, the production of proteins will be affected and low protein level in the blood can cause fluid leaking from blood vessels into the tissues. They include high blood pressure medicines such as calcium channel blockers, diabetes medicines, steroids such as prednisone, NSAIDs(non-steroidal anti-inflammatory drugs), etc. Elevating your legs above the heart while lying or sitting can also help alleviate feet swelling. It usually appears on the wrists or ankles, but may be in the mouth or on the lower back, neck, legs, and genitals. It's a red, scaly rash, sometimes with small erosions of the skin, more often seen in elderly people. For example, granuloma annulare is raised, reddish or flesh-colored bumps forming ring patterns that can be found on the hands and feet.
Jorizzo, MD, professor and founding chair of dermatology, Wake Forest University, Winston-Salem, N.C. It is intended for general informational purposes only and does not address individual circumstances.
You should be aware that whenever you delay the treatment for this skin condition, it becomes severe and symptoms are severe also. However, there are some individuals who are experiencing this and they age from 10-35 years old. The only thing is, you need to have it moderately since over doing it will result to sunburn. What people don’t ask about though is WHY they are experiencing these eye symptoms and what they can do to eliminate the cause. The type caused by pools of liquid is often caused by excessive liquid intake overworking the kidneys with frequent urination, leading to inflammation. If this build-up is not removed from the area, puffy eyes are the least serious of the symptoms that can occur. The consumption of mucus and fat-containing foods such as dairy products, meat, poultry, sugar, refined grains, and oils.
Think about whether or not you drink enough water on a daily basis for your weight; also take an honest and unbiased look at your diet. However, if someone has dark “circles” under the eyes, redness or a purplish hue, a yellowish tone, or even a grayish color, the practitioner automatically knows that something is out of whack. Capillaries distend when the area is lacking nutrition; they expand to try to take in more nutrients whether they are present or not. Again, excessive dairy consumption can be the culprit of this discoloration, in addition to eating too many yellow or orange vegetables such as carrots and members of the squash family. These issues can be caused by excessive ingestion of yang foods such as salt, dairy, animal fats, and meat. The delicate skin around the eyes does not have the ability to absorb heavy creams or products containing ingredients with large molecules. TCM considers milia to be hardened deposits of mucus, fat, and oil from a diet that consists of too many animal proteins and fats (dairy, oily fish, eggs, poultry, and meat), as well as sugar. Practitioners of TCM even associate the development of certain physical features with certain foods the mother consumes while pregnant. A lot of the health issues indicated by the eyes can be addressed by diet & lifestyle changes, but also by adjusting your skincare routine to properly align with your skin type. She’s a holistic skincare and nutrition entrepreneur, award-winning coach, product formulator, speaker, and educator. My ex wife took him to dermatoligists and none have expressed concern nor can they tell me what it is. I can’t make any diagnoses, but I would definitely recommend you take him to a holistic practitioner like a naturopathic or homeopathic doctor to have it looked at. Unfortunately I can only give general advice in this format–if you’d like personalized advice, please schedule a Hash it Out phone or Skype session!
Though I wasn’t sold on that being why I have these sudden disgusting bags under my eyes.
I can give you personal recommendations in a Hash it Out session–click HERE to learn more and schedule your session. I don`t drink any alcohol or coffee and I don`t consume any sugar and only very little amount of salt. For a consultation and personalized recommendations, please schedule a Hash it Out session.
Epsom SaltEpsom salt works fast to reduce swelling and can help alleviate pain and discomfort, too.
As recognized by the same authors, this study is unique by screening such patients with the gold-standard technique of proton magnetic resonance spectroscopy and performing a liver biopsy when possible to assess for NASH. This suggests that serum aminotransferase levels are insensitive markers for the detection of NAFLD and that the a€?normala€? reference values for these serum liver enzymes currently used to exclude NAFLD need to be challenged and revised. If you are having diabetes and kidney damages, you might have infections in the feet which can cause swelling in the feet.
Therefore if you are taking these drugs, it is very important to consult your doctor and test these drugs to see whether feet swelling is caused by these drugs.
It can first appear as a dull, reddish colored patch but then become shinier with a distinct border. These are signs of a rare genetic disease called tuberous sclerosis that causes benign tumors to grow in the brain and other vital organs.
It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. It cannot be felt with the fingertips below the edge of the ribs, except when you take a deep breath. You may have heard of the skin problem rosacea but you are not fully aware what causes it and its symptoms.


This chronic skin problem can cause you to become blind which you definitely don’t want to happen.
It’s not their fault…we live in a society dominated by allopathic, or Western Medicine which focuses on treating and alleviating symptoms after they appear rather than actually finding the underlying causes, eliminating or reducing those, and preventing the symptoms from returning again in the long term.
This type is less likely in Western cultures though, since the majority of the general public is perpetually dehydrated.
Bacterial and fungal overgrowth in this area can lead to health issues such as inflammation of the prostate glands, uterus and ovaries; which can eventually develop into cysts and tumors, some of which can be cancerous. The Standard American Diet (SAD) recommends multiple servings of these foods on a daily basis, which is unfortunate, but could explain why so many Americans suffer from disorders of the kidneys, and also are willing to spend an arm and a leg on expensive products and procedures to eliminate eyebags. If you have any of these issues, you might want to consider limiting your consumption of these foods and replacing them with whole, raw, living foods. Dilated capillaries can also suggest excessive stress, nervousness, anxiety, or other mental disharmonies.
Again, yellowish discoloration can point to an excretory issue, but in serious cases can point to serious liver diseases like cirrhosis or hepatitis. To treat existing ones, the safest way is to go to a trained aesthetician, cosmetic nurse, or physician and have them extracted with the assistance of a sterile lancet or needle. In my Create Your Skincare course, students learn about how to create a customized eye moisturizer specifically suited to their own skin, but there are some high-quality brands out there as well. Disproportionate intake of these foods also can lead to high cholesterol and other cardiovascular problems, which is why milia are sometimes referred to as “cholesterol deposits” in aesthetics. Often, one’s dietary and lifestyle choices and norms were learned from parents or cultural traditions. Rachael combines different holistic modalities to help people with skin conditions and self-image issues heal physically, emotionally, and spiritually so they can live their lives with joy and confidence.
They have a broader range of knowledge in different treatment options than allopathic doctors do.
Hormone imbalances can certainly put stress on the endocrine system as a whole–especially the adrenals which are located on top of the kidneys. That way we can go through the different foods and products in your diet and regimen and see if we can find the culprit. It’s certainly true though that lack of sleep prevents the body from performing its functions optimally and also hinders its natural healing process, so it certainly is an underlying factor. The magnesium sulfate in Epsom salt is easily absorbed through the skin and helps improve circulation and reduce swelling. Notably, this study shows that approximately half (56%) of these patients with T2DM and normal aminotransferase levels have NASH, the more advanced form of NAFLD. Unfortunately, sometimes it is a sign of lupus," says University of Miami dermatologist Paolo Romanelli, MD.
In rare cases acanthosis nigricans occurring in other places, such the hands or lips, may indicate an internal cancer. Researchers only recently found that the dye used during MRI exams triggers this condition in some people with kidney disease.
Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. According to TCM, greatly reducing or eliminating these foods from one’s diet will not only reduce or eliminate puffy eyelids and eyebags, but will also correct the internal cause. In TCM, any of these symptoms can be linked to an overworked cardiovascular system due to the excessive consumption of yin foods and beverages such as sugar and alcohol.
Each states have different regulations regarding the use of needles and lancets in aesthetics, so in certain states you might have to go to a cosmetic or dermatologic doctor or nurse.
Look for a lightweight, high quality eye cream or serum that is formulated with smaller molecules that will not get trapped and cause deposits underneath the skin.
Aestheticians are often taught to suggest that clients with milia in the eye area have their cholesterol levels checked. These choices and routines can be changed, which can then eliminate the causes of these eye symptoms.
As a mentor, she helps professionals in the aesthetics and nutrition fields build their businesses and truly serve their clients in meaningful and sustainable ways. Contrast HydrotherapyThis type of hydrotherapy, which includes both cold and warm water, is highly effective for reducing swelling in your feet. NASH has the potential to progress to cirrhosis, liver failure, and hepatocellular carcinoma (HCC).
Another cause is loss of proteins in urine and low albumin in the blood which can cause decreased plasma colloid osmotic pressure and fluid being accumulated in tissues.
Fair skinned people would always complain about this type of skin problem and there are millions of them who are suffering from it.
The honest answers to those questions will help determine the type and cause of your eye puffiness.
Regular consumption and absorption of certain chemicals and medications in addition to refined sugars can also interfere with the function of the excretory and nervous systems, and often present with purplish discoloration of the eye area. Restricting these foods in one’s diet will help prevent future milia from forming, as well as the health conditions associated with them.
Rachael is the creator of the popular skincare and lifestyle blog Holistically Haute™, as well as the online course, Create Your Skincare™. Good thing my wife knows how to do the massage for me since she has basic training on massaging. Great post by the way!Sharath September 5, 2015 at 7:56 pm ReplyHi , first of all,thanks for the post,appreciate the knowledge sharing. It creates pressure on the affected area that helps relax sore muscles and improve circulation. DandelionThe diuretic property of dandelion helps the body metabolize extra fluids, making it a great remedy for swollen feet. Just place ur feet on two to three soft pillows while sleeping,ensure that its not too high and make ur leg and joints strain or uncomfortable,let it be in a comfortable height.by doing this the excess liquid goes out of the body through urine, you can do it at night if you are comfortable waking up to empty your bladder, do it at the time of rest and trust me its the best way to get edema or swelling down.
Lemon WaterDrinking lemon water helps flush out excess fluid and toxins from your body, which can reduce swelling in the feet and other areas of the body caused by water retention.



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