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Those patients who find Viagra type tablets less than optimal or who can’t tolerate the side effects are otherwise left with the prospect of penile injections. Over 2,000 physicians and urologists have prescribed TriMix-gel® for dissatisfied ED patients. The information contained on this website is general in nature and is intended for use as an informational aid. NO is the physiologic signal essential to penile erection because NO is required for the activation of soluble guanylate cyclase to convert guanosine triphosphate to cyclic guanosine monophosphate (cGMP). Recent studies show that natural agents, specifically, the NO-producing substrates, L-arginine and L-citrulline, can do so. Furthermore, L-arginine, in addition to its roles as substrate for NOS and arginase, is also a precursor for the synthesis of proteins, urea, creatine, vasopressin, and agmatine. In contrast, L-citrulline escapes intestinal or liver metabolism, and enters the kidneys where it is rapidly converted into L-arginine. Improvement in the erection hardness score from 3 (mild ED--penile rigidity that still allowed some kind of vaginal penetration, but not satisfactory penetration or completion of successful intercourse) to 4 (normal erectile function) occurred in 12 (50%) of the men when taking L-citrulline, and in 2 of the 24 men when taking placebo. In 2008, it was shown that increased NO production induces corpus cavernosum smooth muscle cell synthesis and the secretion of vascular endothelial growth factor (VEGF), which can restore impaired endothelial function. Clinical Pearl: L-citrulline may be of great benefit for your female postmenopausal patients as well. Supplementation with the NO-boosting substances, L-citrulline and L-arginine, along with antioxidants, has been demonstrated to delay endothelial senescence despite high glucose levels or a high-cholesterol diet.
Given PDE5-inhibitors’ potential for adverse side-effects, a trial of supplementation with L-citrulline, which has been proven to be safe, effective, and psychologically well accepted by patients, and is significantly less expensive than the PDE5-inhibitor drugs, certainly deserves consideration.
Even more importantly for your patient’s long term health and longevity, PDE5-inhibitors do nothing to improve NO production, while using L-citrulline to increase L-arginine availability does. Supplementation with L-citrulline may increase the body’s production of nitric oxide (NO) more effectively than L-arginine. The NO donor L-arginine is a semi-essential amino acid present in dietary proteins and produced in the body from L-citrulline, another semi-essential amino acid present in watermelon and synthesized in the intestinal tract from glutamine. It has long been known that ASS1 argininosuccinate synthetase, involved in the synthesis of arginine and catalyzing that condensation of citrulline and aspartate to argininosuccinate using ATP, is co-adjacent to the ABO locus. IMPORTANT QUESTION: Can one take Cialis or Viagra WITH Arginine and or Citruline as a way of potentiating the effects of the ED Medication. Lara Pizzorno is a member of the American Medical Writers Association with 25+ years of experience writing for physicians and the public, Lara is Editor for Longevity Medicine Review as well as Senior Medical Editor for SaluGenecists, Inc.



Viagra is a wonderful drug for sexual relationships as it helps fight the problem of erectile dysfunction. Several recent studies have shown that the recreational use of Viagra has gone up among youngsters.
Many doctors believe that youngsters should not use the drug as long as they are not suffering from ED. You shouldn’t take the drug if you are taking other medicines that are used to treat chest pain, hypertension and other such ailments. Though all possible measures have been taken to ensure accuracy, reliability, timeliness and authenticity of the information; Onlymyhealth assumes no liability for the same.
The active ingredients are energized into a gel at time of use, then applied at the penis tip. It does not cover all possible uses, actions, precautions, side effects, or interactions of the products shown, nor is the information intended as medical advice or diagnosis for individual health problems or for making an evaluation as to the risks and benefits of using a particular product. L-arginine is produced in the body from L-citrulline, and the most recently published research (discussed below) suggests supplementation with L-citrulline, rather than L-arginine, is the better option. All patients reporting an erection hardness score improvement from 3 to 4 were highly satisfied. This provides a rationale for L-citrulline supplementation to not only manage, but reverse penile endothelial dysfunction by correcting the proximate cause of ED. Supplementing your ED patients with L-citrulline can provide systemic as well as sexual performance benefits. This may explain why ABO seems to be a major distinguishing factor in the response by newborns to inhaled NO therapy.
It is recommended just to get an erection during ED problem and it’s not at all an aphrodisiac or libido booster.
Young men may use the drug as an aphrodisiac or to boost libido however it doesn't offer such benefits. Some studies strictly recommend not to use Viagra unless suffering from ED and prescribed by a medical care provider. Your body can get dependent on Viagra and you may later on find it hard to get an erection without the drug. Some of the other common side-effects are facial flushing, headaches, liver problems, blurred vision and sensitivity to light.
If you have or suspect having any medical condition, kindly contact your professional health care provider.


9,005,183, “A System and Method for Treating Erectile Dysfunction” for the novel ED alternative, TriMix-gel®. 9,005,183 because no one has ever contemplated and executed this innovative approach until TriMix-gel®. The doctor can write you a prescription, fax it to the pharmacy and the pharmacy will call the patient for payment and shipping information. Although much of the information on this site is derived from the medical literature, you should consult your Doctor about diagnosis and treatment of any health problems. At the month 2-visit, the men were informed they had received a commercially available nutrient and given the option to continue it or to receive a prescription for a PDE-5 inhibitor.
Researchers have recently shown a close relationship between atherosclerosis and endothelial senescence--and that NO can prevent it—especially in a diabetic model. Reasons like poor blood flow to the penis, too much alcohol, medications, or chronic illnesses can cause erectile dysfunction. While the drug seems perfect for men in 50s or 60s it doesn't seem to be the right choice for young men. However if you are experiencing ED at young age, your doctor may prescribe the drug to you as well.
TriMix-gel integrates patient friendly, inventive approaches with patented technology to give dissatisfied ED patients a clinically tested ED alternative. Information and statements on this website have not been evaluated by the Food and Drug Administration (FDA).
They are compounded in a licensed compounding pharmacy for the use of an individual patient who has been prescribed these products by a licensed physician. This website is not intended for making an evaluation as to the suitability, risks or benefits of use. Short-term effects of l-citrulline supplementation on arterial stiffness in middle-aged men.. Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction.



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